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1: Childs Brain. 1976;2(5):273-89.Links

Choroid plexus papilloma. I. Proof of cerebrospinal fluid overproduction.

Milhorat TH, Hammock MK, Davis DA, Fenstermacher JD.

Utilizing a ventricular perfusion technique, the rate of CSF formation was determined in a 2-year-old child before and after removal of a 74 g choroid plexus papilloma from the left lateral ventricle. Preoperatively, the CSF formation rate was 1.05 +/- SD 0.01 ml/min (1,656 ml/day). Postoperatively, the CSF formation rate was reduced fivefold to 0.20 +/- SD 0.01 ml/min (288 ml/day). Whereas these data are regarded as conclusive evidence of CSF overproduction by a choroid plexus papilloma, the pathogenesis of generalized ventricular enlargement in this case was due to part to obstruction of the subarachnoid pathways.

PMID: 1022421 [PubMed - indexed for MEDLINE]