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Pathologica. 1998 Dec;90(6):792-7.

[Gastrointestinal autonomic nerve tumor (GANT) associated with Von Recklinghausen's disease].

[Article in Italian]

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  • 1Dipartimento di Oncologia, Universit√† di Bologna.


Here we describe a case of gastrointestinal autonomic nerve tumor (GANT) arosen in a patient with von Recklinghausen's disease. To the best of our knowledge, only four other similar cases have been previously reported in the literature. Histologically, the tumour was composed of spindle shaped cells arranged in short bundles. The neoplastic cells had pleomorphic nuclei and numerous mitoses. Immunohistochemical investigation displayed evidence of neural differentiation. Neoplastic cells were diffusely anti-synaptophysin, anti-neuron specific enolase and anti-vimentin positive. The clinicopathological features of the present case are described and discussed together with those of the other previously reported cases.

[PubMed - indexed for MEDLINE]
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