Send to

Choose Destination
See comment in PubMed Commons below
Neth J Med. 1999 Apr;54(4):167-79.

Performance of subcutaneously implanted glucose sensors for continuous monitoring.

Author information

  • 1Department of Biomaterials, University of Nijmegen, The Netherlands.


Despite a considerable amount of research attributed to the development of an implantable glucose sensor, to date there is no clinically applicable concept for continuous glucose monitoring. Investigations to validate the subcutaneous tissue for continuous glucose sensing mostly comprised short-term implantations of glucose sensors. Most implanted glucose sensors showed a significant drift in sensitivity over the implantation period. This bioinstability was not to be expected from the in vitro performance of the sensors. In this paper, the influence of possible failure mechanisms on the poor in vivo performance of subcutaneously implanted glucose sensors is reviewed.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk