Inhibitory effect of green and black tea on tumor growth

Proc Soc Exp Biol Med. 1999 Apr;220(4):229-33. doi: 10.1046/j.1525-1373.1999.d01-39.x.

Abstract

The administration of green tea, black tea, or (-)-epigallocatechin gallate inhibited the growth of established nonmalignant and malignant tumors in tumor-bearing mice. In experiments with black tea, we found that its oral administration inhibited DNA synthesis and enhanced apoptosis in both nonmalignant and malignant tumors in tumor-bearing mice.

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis / drug effects
  • Catechin / analogs & derivatives*
  • Catechin / therapeutic use
  • DNA Replication / drug effects
  • DNA, Neoplasm / drug effects
  • Mice
  • Neoplasms, Experimental / pathology
  • Neoplasms, Experimental / prevention & control*
  • Phytotherapy*
  • Plant Extracts / therapeutic use
  • Tea / therapeutic use*

Substances

  • DNA, Neoplasm
  • Plant Extracts
  • Tea
  • Catechin
  • epigallocatechin gallate