Biometals. 1998 Dec;11(4):399-404.

Annexins.

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Department of Physiology, Boston University School of Medicine, MA 02118, USA.

Abstract

The annexins are a family of proteins that bind anionic phospholipid surfaces in a Ca(2+)-dependent manner (general reviews include Raynal & Pollard 1994, Swairjo & Seaton 1994, Seaton 1996, Mollenhauer, 1997). Due to this functional property, individual annexins have been discovered independently by numerous laboratories with diverse experimental goals. Ca2+ characteristically causes the annexins to shift from a soluble to membrane associated state. This shift is believed to be the mechanism that underlies annexin cellular function.

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Structure-function correlations of calcium binding and calcium channel activities based on 3-dimensional models of human annexins I, II, III, V and VII. [J Biomol Struct Dyn. 1993]
Structure-function correlations of calcium binding and calcium channel activities based on 3-dimensional models of human annexins I, II, III, V and VII.
Chen JM, Sheldon A, Pincus MR. J Biomol Struct Dyn. 1993 Jun; 10(6):1067-89.
Review Annexins: linking Ca2+ signalling to membrane dynamics. [Nat Rev Mol Cell Biol. 2005]
Review Annexins: linking Ca2+ signalling to membrane dynamics.
Gerke V, Creutz CE, Moss SE. Nat Rev Mol Cell Biol. 2005 Jun; 6(6):449-61.
Structure of membrane-bound annexin A5 trimers: a hybrid cryo-EM - X-ray crystallography study. [J Mol Biol. 2000]
Structure of membrane-bound annexin A5 trimers: a hybrid cryo-EM - X-ray crystallography study.
Oling F, Santos JS, Govorukhina N, Mazères-Dubut C, Bergsma-Schutter W, Oostergetel G, Keegstra W, Lambert O, Lewit-Bentley A, Brisson A. J Mol Biol. 2000 Dec 8; 304(4):561-73.
Review Annexin structure and membrane interactions: a molecular perspective. [Annu Rev Biophys Biomol Struct...]
Review Annexin structure and membrane interactions: a molecular perspective.
Swairjo MA, Seaton BA. Annu Rev Biophys Biomol Struct. 1994; 23:193-213.
Review Annexins--unique membrane binding proteins with diverse functions. [J Cell Sci. 2004]
Review Annexins--unique membrane binding proteins with diverse functions.
Rescher U, Gerke V. J Cell Sci. 2004 Jun 1; 117(Pt 13):2631-9.

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Cited by 5 PubMed Central articles

Review Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. [Br J Pharmacol. 2008]
Review Annexin-A1: a pivotal regulator of the innate and adaptive immune systems.
D'Acquisto F, Perretti M, Flower RJ. Br J Pharmacol. 2008 Sep; 155(2):152-69. Epub 2008 Jul 21.
Apo and calcium-bound crystal structures of Alpha-11 giardin, an unusual annexin from Giardia lamblia. [J Mol Biol. 2007]
Apo and calcium-bound crystal structures of Alpha-11 giardin, an unusual annexin from Giardia lamblia.
Pathuri P, Nguyen ET, Svärd SG, Luecke H. J Mol Biol. 2007 Apr 27; 368(2):493-508. Epub 2007 Feb 20.
Valproic acid teratogenicity: a toxicogenomics approach. [Environ Health Perspect. 2004]
Valproic acid teratogenicity: a toxicogenomics approach.
Kultima K, Nyström AM, Scholz B, Gustafson AL, Dencker L, Stigson M. Environ Health Perspect. 2004 Aug; 112(12):1225-35.

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