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Int J Oral Maxillofac Surg. 1999 Apr;28(2):125-8.

Adenosquamous carcinoma of the mouth: a rare variant of squamous cell carcinoma.

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  • 1Eastman Dental Institute for Oral Health Care Sciences, University of London, UK. Cscully@eastman.ucl.ac.uk


Adenosquamous carcinoma is a rare tumour in the oral cavity and is characterised histologically by carcinomatous change in surface epithelium, in association with adenocarcinoma affecting the ducts of minor salivary glands. Only a dozen cases have previously been reported in the oral cavity, but all have shown an aggressive course with 60% of patients dying of disease. We report three further cases and review the literature, which suggests that this lesion should be regarded as a high-grade variant of squamous cell carcinoma.

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