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Gynecol Oncol. 1999 Apr;73(1):119-20.

Frequency of invasive cancer in surgically excised vulvar lesions with intraepithelial neoplasia (VIN 3).

Author information

  • 1Division of Gynecologic Oncology, University of Cincinnati College of Medicine, Cincinnati, Ohio, 45267-0526, USA.

Abstract

OBJECTIVE:

The aim of this study was to determine the frequency of invasive cancer found from specimens removed by surgical excision on patients with diagnosis of VIN 3.

METHODS:

Seventy-eight patients with biopsy-proven vulvar intraepithelial neoplasia 3 (VIN 3) were treated by surgical excision.

RESULTS:

Sixteen patients (20.5%) were found to have invasion in the excised surgical specimen. Superficial invasion was seen in 7 patients (9%), 9 were noted to have >1 mm invasion (11.5%), and 1 patient had in situ Paget's disease (1.3%).

CONCLUSION:

Surgical excision should be considered a preferable method in management of patients with VIN 3.

Copyright 1999 Academic Press.

PMID:
10094891
[PubMed - indexed for MEDLINE]
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