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Emergency Medicine and Trauma Center, Methodist Hospital, Clarian Health Partners, Indiana University School of Medicine, Indianapolis, IN, USA.
Because decisions regarding therapy are so common in clinical practice, the application of number needed to treat (NNT) is one of the most important evidence-based medicine skills to be acquired. NNT provides a clinically useful "yardstick" of the effort required to have a beneficial outcome or prevent a bad outcome with a therapy. A brief overview of the concept, derivation, and application of NNT is presented.
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