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    Bone Marrow Transplant. 1999 Feb;23(3):299-301.

    Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation.

    Source

    Department of Oncology, Shariati Hospital, Tehran University of Medical Science, Iran.

    Abstract

    Dyskeratosis congenita is recognized by its dermal lesions and constitutional aplastic anemia in some cases. We report successful allogeneic bone marrow transplantation in two siblings with this disease from their sister, and their long term follow-up. We used reduced doses of cyclophosphamide and busulfan for conditioning instead of total body irradiation. Also, we report late adverse effects of transplantation which are not distinguishable from the natural course of disease.

    PMID:
    10084264
    [PubMed - indexed for MEDLINE]
    Free full text

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