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Science. 1999 Mar 19;283(5409):1911-4.

Signaling of cell fate decisions by CLAVATA3 in Arabidopsis shoot meristems.

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  • 1California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.

Abstract

In higher plants, organogenesis occurs continuously from self-renewing apical meristems. Arabidopsis thaliana plants with loss-of-function mutations in the CLAVATA (CLV1, 2, and 3) genes have enlarged meristems and generate extra floral organs. Genetic analysis indicates that CLV1, which encodes a receptor kinase, acts with CLV3 to control the balance between meristem cell proliferation and differentiation. CLV3 encodes a small, predicted extracellular protein. CLV3 acts nonautonomously in meristems and is expressed at the meristem surface overlying the CLV1 domain. These proteins may act as a ligand-receptor pair in a signal transduction pathway, coordinating growth between adjacent meristematic regions.

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PMID:
10082464
[PubMed - indexed for MEDLINE]
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