J Toxicol Clin Toxicol. 1999;37(1):99-101.

Nonconvulsive status epilepticus in theophylline toxicity.

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Department of Pulmonary, New York University, New York 10016, USA. krieg01@gcrc.med.nyu.edu

Abstract

CASE REPORT: A 53-year-old cocaine user was on chronic therapy with theophylline, albuterol, and ipratropium for asthma and nifedipine for hypertension. Acute asthma treatment that increased the serum theophylline to 35 micrograms/mL was associated with tonic clonic seizures followed by bizarre, lateralized posturing. Electroencephalogram seizure activity lasting 10 days was consistent with nonconvulsive status epilepticus, Complex Partial, type II. Theophylline was considered the probable instigator of this underdiagnosed neurologic disorder.

PMID:: 10078166; [PubMed - indexed for MEDLINE]

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