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Neurology. 1999 Feb;52(3):654-7.

Cortical dysplasia with angiodysgenesis and chronic inflammation in multifocal partial epilepsy.

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  • 1Department of Neuropathology, The National Hospital for Neurology and Neurosurgery, London, UK. MThom@ion.ucl.ac.uk


A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia. MRI showed diffuse enhancement of the left temporoparieto-occipital white matter and cortical thickening of the left medial temporal lobe. The resected temporal lobe revealed cortical dysplasia and angiodysplasia with foci of more recent ischemic necrosis and chronic inflammation as an explanation for the clinical deterioration.

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