Clin Exp Allergy. 1998 Dec;28(12):1591-3.

Baker's asthma due to the enzyme xylanase -- a new occupational allergen.

Baur X, Sander I, Posch A, Raulf-Heimsoth M.

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Professional Associations' Research Institute for Occupational Medicine, University of Bochum, Germany.

Abstract

The asthmatic baker showed IgE-mediated sensitization to xylanase of Aspergillus niger used as a baking additive. Inhalative challenge with approximately 0.5 microg of the enzyme resulted in an immediate-type asthmatic reaction. This case, as well as a preliminary screening of symptomatic bakers, shows that xylanase is a further relevant type I-sensitizer in the baking industry.

PMID:: 10024232; [PubMed - indexed for MEDLINE]

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