Antibiotiki. 1975 Jun;20(7):653-7.

[Toxicological characteristics of ampicillin].

[Article in Russian]

Khosid GM, Shteĭnberg GB, Balabanova EL, Baru RV, Churagulova NK.

Abstract

Toxocity of ampicillin trihydrate was studied in acute and chronic experiments. It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect. On its inhalation in concentrations of 5 mg/m3 for 4 months, ampicillin induced allergization of albino rats, decreased their immunity. The general toxic effect of the drug was slightly pronounced. Ampicillin in a concentration of 0.1 mg/m3 induced tension of the immunological reactivity of the organism. The maximum permissible concentration (MPC) of ampicillin in the working premises equal to 0.1 mg/m3 is recommended. Mark "Allergen" is necessary.

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[Toxicological characteristics of ampicillin].
[Toxicological characteristics of ampicillin].
Antibiotiki. 1975 Jun ;20(7):653-7.

PubMed
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