RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; Sh - Protein

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Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. [Nat Commun. 2024]
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma.
Thongon N, Ma F, Baran N, Lockyer P, Liu J, Jackson C, Rose A, Furudate K, Wildeman B, Marchesini M, et al. Nat Commun. 2024 Feb 8; 15(1):1203. Epub 2024 Feb 8.
Estrogen upregulates DNA2 expression through the PI3K-AKT pathway in endometrial carcinoma. [J Zhejiang Univ Sci B. 2023]
Estrogen upregulates DNA2 expression through the PI3K-AKT pathway in endometrial carcinoma.
Wang X, Xu X, Zhang T, Jin Y, Xu S, Chen L, Lai Y, Zhang L, Pan R, Yu Y. J Zhejiang Univ Sci B. 2023 Mar 15; 24(3):262-268.
DNA2 mutation causing multisystemic disorder with impaired mitochondrial DNA maintenance. [J Hum Genet. 2022]
DNA2 mutation causing multisystemic disorder with impaired mitochondrial DNA maintenance.
Sun J, Su W, Deng J, Qin Y, Wang Z, Liu Y. J Hum Genet. 2022 Dec; 67(12):691-699. Epub 2022 Sep 5.

RefSeq genomic sequence
See the genomic reference sequence for the DNA2 gene (NG_034247.1).
RefSeq protein isoforms
See 7 reference sequence protein isoforms for the DNA2 gene.

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Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
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ExactAntigen/Labome

RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; Short=hDNA2;...
RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2; Short=hDNA2; AltName: Full=DNA replication ATP-dependent helicase-like homolog; Includes: RecName: Full=DNA replication nuclease DNA2; Includes: RecName: Full=DNA replication ATP-dependent helicase DNA2
gi|119370373|sp|P51530.3|DNA2_HUMAN

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