RecName: Full=Beta-secretase 2; AltName: Full=Beta-site amyloid precur - Protein

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BACE2 expression increases in human neurodegenerative disease. [Am J Pathol. 2012]
BACE2 expression increases in human neurodegenerative disease.
Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, et al. Am J Pathol. 2012 Jan; 180(1):337-50. Epub 2011 Nov 7.
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic β-cells. [FASEB J. 2015]
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic β-cells.
Alcarraz-Vizán G, Casini P, Cadavez L, Visa M, Montane J, Servitja JM, Novials A. FASEB J. 2015 Jan; 29(1):95-104. Epub 2014 Oct 23.
β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression. [Eur J Neurosci. 2011]
β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression.
Bettegazzi B, Mihailovich M, Di Cesare A, Consonni A, Macco R, Pelizzoni I, Codazzi F, Grohovaz F, Zacchetti D. Eur J Neurosci. 2011 Jan; 33(2):236-43. Epub 2010 Nov 14.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Bace2 gene.

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Protein