RecName: Full=E3 ubiquitin-protein ligase HERC2; AltName: Full=HECT do - Protein

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Mechanism of orphan subunit recognition during assembly quality control. [Cell. 2023]
Mechanism of orphan subunit recognition during assembly quality control.
Yagita Y, Zavodszky E, Peak-Chew SY, Hegde RS. Cell. 2023 Aug 3; 186(16):3443-3459.e24. Epub 2023 Jul 21.
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway. [J Exp Clin Cancer Res. 2023]
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, Zhou J, Lu X, Zhang L, Chen Z, et al. J Exp Clin Cancer Res. 2023 Feb 1; 42(1):38. Epub 2023 Feb 1.
The ZZ domain of HERC2 is a receptor of arginylated substrates. [Sci Rep. 2022]
The ZZ domain of HERC2 is a receptor of arginylated substrates.
Tencer AH, Liu J, Zhu J, Burkholder NT, Zhang Y, Wu W, Strahl BD, Ohta T, Kutateladze TG. Sci Rep. 2022 Apr 11; 12(1):6063. Epub 2022 Apr 11.

RefSeq genomic sequence
See the genomic reference sequence for the HERC2 gene (NG_016355.1).
RefSeq protein isoforms
See 34 reference sequence protein isoforms for the HERC2 gene.

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O95714 [Domain Mapping of Disease Mut...]
O95714
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=E3 ubiquitin-protein ligase HERC2; AltName: Full=HECT domain and R...
RecName: Full=E3 ubiquitin-protein ligase HERC2; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2
gi|308153453|sp|O95714.2|HERC2_HUMA

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