Homo sapiens ribonucleotide reductase regulatory subunit M2 (RRM2), tr - Nucleotide

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Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor. [J Exp Clin Cancer Res. 2023]
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
Giang LH, Wu KS, Lee WC, Chu SS, Do AD, Changou CA, Tran HM, Hsieh TH, Chen HH, Hsieh CL, et al. J Exp Clin Cancer Res. 2023 Dec 20; 42(1):346. Epub 2023 Dec 20.
E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. [Biochem Pharmacol. 2023]
E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma.
Liu K, Wang L, Lou Z, Guo L, Xu Y, Qi H, Fang Z, Mei L, Chen X, Zhang X, et al. Biochem Pharmacol. 2023 Dec; 218:115854. Epub 2023 Oct 19.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. [Cell. 2023]
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, et al. Cell. 2023 Oct 26; 186(22):4898-4919.e25. Epub 2023 Oct 11.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the RRM2 gene (NM_001165931.1).
RefSeq protein product
See the reference protein sequence for ribonucleoside-diphosphate reductase subunit M2 isoform 2 (NP_001025.1).

Protein
Protein sequence from Nucleotide coding region
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GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
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Homo sapiens ribonucleotide reductase regulatory subunit M2 (RRM2), transcript v...
Homo sapiens ribonucleotide reductase regulatory subunit M2 (RRM2), transcript variant 2, mRNA
gi|1519245390|ref|NM_001034.4|

Nucleotide

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Nucleotide