PREDICTED: ubiquitin-conjugating enzyme E2 N [Lipotes vexillifer]

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Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. [Sci Transl Med. 2022]
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia.
Barreyro L, Sampson AM, Ishikawa C, Hueneman KM, Choi K, Pujato MA, Chutipongtanate S, Wyder M, Haffey WD, O'Brien E, et al. Sci Transl Med. 2022 Mar 9; 14(635):eabb7695. Epub 2022 Mar 9.
Echinococcus multilocularis infection induces UBE2N suppression via exosomal emu-miR-4989. [Acta Trop. 2021]
Echinococcus multilocularis infection induces UBE2N suppression via exosomal emu-miR-4989.
Cai M, Ding J, Li Y, He G, Yang J, Liu T, Guo X, Yang X, Wang X, Cho WC, et al. Acta Trop. 2021 Nov; 223:106087. Epub 2021 Aug 10.
Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. [Nat Commun. 2020]
Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Puvar K, Iyer S, Fu J, Kenny S, Negrón Terón KI, Luo ZQ, Brzovic PS, Klevit RE, Das C. Nat Commun. 2020 May 12; 11(1):2365. Epub 2020 May 12.

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