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    P-glycoprotein [Homo sapiens]

    GenBank: CAA41558.1

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      Supplemental Content

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      Analyze this sequence

      • Run BLAST
        Find regions of similarity between this sequence and other sequences using BLAST.
      • Identify Conserved Domains
        View conserved domains detected in this protein sequence using CD-search.
      • Highlight Sequence Features
        Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
      • Find in this Sequence
        Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

      Articles about the ABCB1 gene

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      Pathways for the ABCB1 gene

      • Codeine and morphine metabolism
        Codeine and morphine metabolismThe principal pathways for metabolism of codeine occur in the liver, although some metabolism occurs in the intestine and brain. Approximately 50-70% of codeine is converted to codeine-6-glucuronide b ... [bsid198831]
      • Bile secretion
        Bile secretionBile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins in the small intestine. Moreover, bile is an important route of elimination for excess cholesterol an ... [bsid193146]
      • ABC transporters
        ABC transportersThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a ... [bsid83035]
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      Reference sequence information

      • RefSeq genomic sequence
        See the genomic reference sequence for the ABCB1 gene (NG_011513.1).
      • RefSeq protein
        See the reference protein sequence for multidrug resistance protein 1 (NP_000918.2).

      More about the ABCB1 gene

      Homologs of the ABCB1 gene

      LinkOut to external resources

      Related information

      • BLink
        BLAST Link. Pre-computed sequence similarity results (BLAST) including alignments for the current protein against the NCBI nr protein database. Organism specific, RefSeq and other database subsets are available as well as access to a pre-computed multiple alignment.
      • Related Sequences
        Protein sequences related by sequence similarity (BLAST) score to the current records.
      • BioSystems
        Pathways and other biosystems containing the current proteins.
      • Gene
        Gene records referencing the current protein sequence records. Sequences included in Gene records are added manually by NCBI.
      • Gene Genotype
        Genotype reports for single nucleotide polymorphisms (SNPs) associated with the current records.
      • GeneView in dbSNP
        Geneview in dbSNP showing single nucleotide polymorphisms (SNPs) mapped to the genes associated with the current records.
      • Nucleotide
        Nucleotide records that are the source of protein records in the current set. The protein sequences are generated through translation of coding region features on the nucleotide records.
      • PubMed
        PubMed articles that cite the protein records in the current set. These are articles that report the International Nucleotide Database Collaboration (DDBJ, EMBL, GenBank) records. These articles are also linked to Reference Sequences derived from the GenBank records.
      • PubMed (Weighted)
        PubMed articles associated with the current protein record through related Gene database records. These articles include Reference into Function, citations in related OMIM, and those associated with sequences in the Gene record.
      • Taxonomy
        NCBI Taxonomy entries and classification information for the source organisms of the current set of records.

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