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2 SNPs
2 conserved protein domains
1 HPRD

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Articles about the RAB3B gene

Rab3B immunoexpression in human pituitary adenomas.
Appl Immunohistochem Mol Morphol. 2009 May; 17(3):185-8.

[Appl Immunohistochem Mol Morphol. 2009]
Distinct roles of Rab3B and Rab13 in the polarized transport of apical, basolateral, and tight junctional membrane proteins to the plasma membrane.
Biochem Biophys Res Commun. 2003 Aug 22; 308(2):270-5.

[Biochem Biophys Res Commun. 2003]
Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells.
J Cell Sci. 1996 Sep; 109 ( Pt 9):2265-73.

[J Cell Sci. 1996]
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Identical Proteins for NP_002858.2

RAB3B, member RAS oncogene family [Homo sapiens]
RAB3B, member RAS oncogene family [Homo sapiens]
gi|119627207|gb|EAX06802.1|

[EAX06802]
RAB3B, member RAS oncogene family [Homo sapiens]
RAB3B, member RAS oncogene family [Homo sapiens]
gi|55960073|emb|CAI17027.1|

[CAI17027]
RAB3B, member RAS oncogene family [Homo sapiens]
RAB3B, member RAS oncogene family [Homo sapiens]
gi|55665425|emb|CAH74098.1|

[CAH74098]
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See the pathway(s) and biological system(s) (BioSystems) that contain this protein.

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what's this?BioSystems for NP_002858.2

Tight junction - Epithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of many different proteins that form large complexes. The transmembrane proteins mediate cell adhesion and are thought to constitute the intramembrane and paracellular diffusion barriers. The cytoplasmic 'plaque' contains three major multi-protein complexes consisting largely of scaffolding proteins, the ZO protein complex, the CRB3-Pals1-PATJ complex and the PAR-3-aPKC-PAR-6 complex. The ZO protein complex appears to organize the transmembrane proteins and couple them to other cytoplasmic proteins and to actin microfilaments. Two evolutionarily conserved protein complexes, the CRB3 and PAR complexes are involved in the establishment and maintenance of epithelial cell polarity. Besides these three protein complexes which seem to be constitutively associated at TJs, a number of proteins with different functions has been identified at TJs. These include additional scaffolding proteins like MUPP1 and MAGI-1, adaptor proteins, transcription regulators and RNA processing factors, regulatory proteins like small GTPases and G-proteins, kinases and phosphatases, and heat shock proteins. These are proposed to be involved in junction assembly, barrier regulation, gene transcription, and perhaps other, presently undefined pathways. ...
Tight junctionEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of man ... [bsid83071]

Reference sequences

RefSeq mRNA
See reference mRNA sequence for the RAB3B gene (NM_002867.2).

Gene Information

More about the RAB3B gene

Homologs

Homologs of the RAB3B gene
The RAB3B gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish.

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NCBI Reference Sequence: NP_002858.2

RAB3B, member RAS oncogene family [Homo sapiens]