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Tetrahymena thermophila genome view
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At present, none of the contigs from the current public WGS assembly have been placed on chromosomes so you cannot browse the sequence data by chromosome. You can find sequenced regions of interest by:

  • querying Map Viewer for a known gene name, symbol, or locus-tag, e.g., NPL4 or TTHERM_00069400.
  • querying Map Viewer for accession numbers, e.g., XM_001007778 or NW_001095101.
  • searching Gene for T. thermophila genes that have been annotated on the genome.
  • searching by sequence using BLAST against the genome. Results from a BLAST sequence alignment can be displayed in Map Viewer by clicking on the Genome View button or on the accession numbers of the results.

     Lineage: Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae; Tetrahymena; Tetrahymena thermophila

Tetrahymena thermophila is a free-swimming unicellular protist. This freshwater organism inhabits streams, lakes, and ponds. Like other ciliates, Tetrahymena cells have a complex genome structure. Each cell contains a diploic micronucleus (mic) and a somatic macronucleus (mac).

The two nuclei function independently and have distinct functions and chromosomal arrangements. The mic is organized into 5 pairs of chromosomes and undergoes mitotic and meiotic division but is not transcribed. In contrast, during the formation of the mac, these chromosomes undergo site-specific fragmentation into approximately 200-300 chromosomes ranging in size from 21 kb to >3000 kb to which telomeric ends are added de novo. During this process, approximately 10% of the genome is removed. Mac chromosomes are amplified to a ploidy of approximately 45 copies except for the 21 kb ribosomal DNA minichromosome which is amplified to ~9000 copies. Transcription and translation occur in the macronucleus.

The Institute for Genomic Research (TIGR) has sequenced the macronuclear genome of Tetrahymena thermophila using a whole genome shotgun approach.

The T. thermophila whole genome sequence data as well as scaffold assemblies with annotation are available in GenBank and in RefSeq.

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Last modified: Oct 17 2007

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