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Series GSE52434 Query DataSets for GSE52434
Status Public on Dec 01, 2013
Title Transcriptional responses of mantle cell lymphoma (MCL) lines to IKKB inhibition
Organism Homo sapiens
Experiment type Expression profiling by array
Summary MCL cell lines were treated with DMSO or 5uM AFN700 for 20hrs
This experiment is designed to see if NFKB-target genes are downregulated by inhibition of IKKB in MCL cell lines that are insensitive to ibrutinib (BTK inhibitor) or sotrastaurin (PKC inhibitor)
 
Overall design MCL cells were seeded in 6well dishes and treated for 20hrs with DMSO or 5uM AFN700
 
Contributor(s) Rahal R, Korn J
Citation(s) 24362935
Submission date Nov 15, 2013
Last update date Mar 25, 2019
Contact name Joshua M Korn
E-mail(s) joshkorn@gmail.com
Organization name Novartis
Street address 250 Mass Ave
City Cambridge
State/province MA
ZIP/Postal code 02141
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (16)
GSM1266771 Rec-1 DMSO 0.025% DMSO 20hr
GSM1266772 Rec-1 AFN700 5uM AFN700 20hr
GSM1266773 SP49 DMSO 0.025% DMSO 20hr
Relations
BioProject PRJNA228924

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52434_RAW.tar 77.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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