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Series GSE50120 Query DataSets for GSE50120
Status Public on Jan 22, 2014
Title Runx3 function in splenic NK cells activated in vivo by IL-15.
Organism Mus musculus
Experiment type Expression profiling by array
Summary NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansion following viral infection is IL-2 or IL-15-dependent.
 
Overall design To identify Runx3 regulated genes, NK cells were isolated from spleen of IL15/Ra injected WT and Runx3-/- mice and sorted to obtain 3 subpopulations of immature (CD27) and mature (DP and CD11c) NK cells.
 
Contributor(s) Levanon D, Leshkowitz D, Groner Y
Citation(s) 24421391
Submission date Aug 22, 2013
Last update date Mar 04, 2019
Contact name Joseph Lotem
E-mail(s) joseph.lotem@weizmann.ac.il
Phone 972-8-934-2342
Organization name Weizmann institute of science
Department Molecular genetics
Street address P.O.B 26
City Rehovot
ZIP/Postal code 76100
Country Israel
 
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (18)
GSM1214441 NK_IL15_invivo_CD27_wt1
GSM1214442 NK_IL15_invivo_CD27_wt2
GSM1214443 NK_IL15_invivo_CD27_wt3
This SubSeries is part of SuperSeries:
GSE52625 Runx3 Regulates Interleukin-15-Dependent Natural Killer Cell Activation
Relations
BioProject PRJNA216118

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50120_RAW.tar 78.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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