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The Genome Reference Consortium

Putting sequences into a chromosome context.

The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome. Subsequent analysis has shown that for most mammalian genomes a single tiling path is insufficient to represent a genome in regions with complex allelic diversity. The GRC is now working to create assemblies that better represent this diversity and provide more robust substrates for genome analysis.

Attending Genome Informatics 2014? Register now for the GRC Assembly Workshop!

Transitioning to GRCh38? Try the NCBI Remapping Service, which uses the same assembly-assembly alignments used by the GRC.

Subscribe to the grc-announce email list to receive email notification for all GRC assembly updates.

We are planning to update the zebrafish reference assembly to GRCz10 in early 2014. If you have questions or concerns about this let us know.

Page last updated: January 2, 2014