Genome Assemblies

The GRC has built tools to facilitate the curation of genome assemblies based on the sequence overlaps of long, high quality sequences (Clones and PCR products, not short sequence reads). The GRC currently supports production of assemblies for human, mouse or zebrafish. If your assembly data fits this model and you are interested in using these tools please contact us using the 'Contact Us' page.

Human

The human genome assembly was produced as part of the Human Genome Project (HGP). The previous assembly (NCBI36) was the last one produced by the HGP and was described in 2004(PMID: 15496913); this was the starting point for the GRC. The assembly is based largely on assembling overlapping clone sequences.

Human assembly information

Current Major Assembly	GRCh37
Regions with Alternate Loci	3
Assembly N50	46,395,641 bp
Remaining Gaps	357
Patch Release version	p8
Patches Released	Fix: 69; Novel: 71

More Human assembly statistics...

Mouse

The GRC has produced an updated assembly (GRCm38). This is an update of the last MGSC assembly (MGSCv37) which was described in 2004(PMID: 19468303). The primary assembly is based on assembling overlapping BAC clones derived from the C57BL/6J strain and several loci have sequence available from other strains.

Mouse assembly information

Current Assembly	GRCm38
Regions with Alternate Loci	70
Assembly N50	54,517,951 bp
Remaining Gaps	437

More Mouse assembly statistics...

Zebrafish

The zebrafish genome assembly was produced at the Sanger Institute. The last assembly produced from the original project was Zv9 and will be described in 2010. This assembly is the starting point for the GRC. The assembly is based on assembling overlapping BAC clones and integrating these sequences with the whole genome shotgun assembly.

Zebrafish assembly information

Current Assembly	Zv9
Regions with Alternate Loci	0
Assembly N50	1,551,602
Remaining Gaps	26,921

More Zebrafish assembly statistics...