- Collection Description
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This dbGaP Collection contains all authorized individual-level genomic datasets currently in dbGaP that are approved for General Research Use (GRU) and have no further limitations beyond those outlined in the model Data Use Certification Agreement. Access to this study will include any additional authorized individual-level GRU datasets that become available. Renewal of this study is required annually.
Data Included in this Study
Individual-level genomic data designated for general research use with no further use limitations or restrictions, that is,
- Data use does not require approval by an Institutional Review Board for secondary analyses
- Data have no publication embargo
- Data have no other use limitations (e.g., requirement for collaboration or publication; restricted for use by academic or not-for-profit organizations; restricted to health, medical, and/or biomedical research)
In response to requests from the scientific community, the NIH implemented a change in the procedures for accessing individual-level GRU genomic data. Under the modified procedures, interested investigators can request GRU individual-level genomic datasets with a single application. However, please note that these data have not been harmonized. Additionally, to help expedite the processing of requests for individual-level GRU genomic datasets, the requests will be reviewed by a single, central Data Access Committee. The process for requesting these datasets is identical to the request process for non-GRU individual-level, controlled-access data, such as the expectation that investigators will abide by the NIH Policy for Sharing of Data Obtained in NIH Supported or Conducted Genome-Wide Association Studies and Data Use Certification Agreement.
Effective April 24, 2018, the Data Use Limitations (DUL) for the Genes and Blood Clotting Study (GABC) (phs000304) was updated to Health/Medical/Biomedical, Not-for-profit Use Only (HMB-NPU). Additionally, the submitting institutions have requested the removal of the National Heart, Lung, and Blood Institute (NHLBI) "Grand Opportunity" Exome Sequencing Project (GO-ESP) Lung Cohorts Exome Sequencing Project: Genetic modifiers of Pseudomonas aeruginosa (Pa) lung infection acquisition in cystic fibrosis (phs000254) from the dbGaP Compilation of Individual-Level Genomic Data for General Research Use (dbGaP Compilation) (phs000688). As such, data from studies phs000304 and phs000254 are no longer available as part of the dbGaP Compilation (phs000688). Investigators must submit separate Data Access Requests (DARs) for the two studies and be approved by the NHLBI Data Access Committee.
- Authorized Access
- Studies Included in Collection
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General Research Use (GRU) n=308 studies
Study Accession Study Name Consent Group Subject Count Sample Count SSTR phs000101.v5.p1 Genome-Wide Association Study of Amyotrophic Lateral Sclerosis General Research Use (GRU) 15480 15480 SSTR phs000102.v1.p1 Ischemic Stroke Genetics Study (ISGS) General research use (GRU) 266 266 SSTR phs000126.v2.p1 CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD) General Research Use (GRU) 943 1009 SSTR phs000138.v2.p1 GWAS for Genetic Determinants of Bone Fragility General Research Use (GRU) 1493 1527 SSTR phs000144.v1.p1 NHGRI Tumor Sequencing Project (Lung Adenocarcinoma) General Research Use (GRU) 384 768 SSTR phs000145.v4.p2 POPRES: Population Reference Sample General Research Use (GRU) 8012 8012 SSTR phs000160.v1.p1 Genetics Consortium for Late Onset of Alzheimer's Disease (LOAD CIDR Project) General Research Use (GRU) 1137 1188 SSTR phs000168.v2.p2 NIA - Late Onset Alzheimer's Disease and National Cell Repository for Alzheimer's Disease Family Study: Genome-Wide Association Study for Susceptibility Loci General Research Use (GRU) 3007 3064 SSTR phs000169.v1.p1 Whole Genome Association Study of Visceral Adiposity in the HABC Study General Research Use (GRU) 2802 2860 SSTR phs000204.v1.p1 Genetic Analysis of Limb Malformation Disorders: Freeman Sheldon Syndrome Exome Sequencing Study (LMD-FSS) Freeman Sheldon Syndrome Exome - General Research Use (GRU) 3 3 SSTR phs000205.v6.p2 International Standards for Cytogenomic Arrays General Research Use (GRU) 53936 49013 SSTR phs000215.v2.p1 Genome-Wide Association Analysis of Biomarkers in the InCHIANTI and BLSA General Research Use (GRU) 0 0 phs000221.v1.p1 NHLBI Family Heart Study (FamHS) General Research Use (GRU) 0 0 phs000222.v6.p2 PREDICT-HD Huntington Disease Study General Research Use (GRU) 1485 0 SSTR phs000244.v1.p1 Genetic Analysis of Limb Malformation Disorders: Miller Syndrome Sequencing Study (LMD-MS) Miller Syndrome Exome - General Research Use (GRU) 6 8 SSTR phs000274.v1.p1 Genome-Wide Association Study of Celiac Disease General Research Use (GRU) 2300 2295 SSTR phs000276.v2.p1 STAMPEED: Northern Finland Birth Cohort 1966 (NFBC1966) General Research Use (GRU) 5415 10931 SSTR phs000290.v1.p1 NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Pulmonary Arterial Hypertension) General Research Use (GRU) 96 94 SSTR phs000291.v2.p1 NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Lung Health Study of Chronic Obstructive Pulmonary Disease) General Research Use (GRU) 337 337 SSTR phs000293.v1.p1 The Familial Intracranial Aneurysm Linkage Study (FIA) General Research Use (GRU) 2507 2073 SSTR phs000294.v1.p1 STAMPEED: Myocardial Infarction Genetics Consortium (MIGen) General Research Use (GRU) 6042 6042 SSTR phs000298.v4.p3 Autism Sequencing Consortium (ASC) General Research Use (GRU) 2509 2509 SSTR phs000344.v1.p1 Genome-Wide Association Study of Amyotrophic Lateral Sclerosis in Finland General Research Use (GRU) 896 896 SSTR phs000349.v1.p1 SNPs and Extent of Atherosclerosis (SEA) Study General Research Use (GRU) 1068 1068 SSTR phs000354.v1.p1 NHLBI GO-ESP Family Studies: Pulmonary Arterial Hypertension General Research Use (GRU) 12 12 SSTR phs000355.v1.p1 Genome Wide Association for Asthma and Lung Function General Research Use (GRU) 0 0 phs000366.v1.p1 NHLBI: Cooperative Study of Sickle Cell Disease (CSSCD) General Research Use (GRU) 0 0 phs000371.v2.p1 Genetic Modifiers of Huntington's Disease General Research Use (GRU) 1206 1454 SSTR phs000374.v1.p1 Genomic Sequencing of Colorectal Adenocarcinomas General Research Use (GRU) 9 18 SSTR phs000379.v1.p1 Genetic Epidemiology Network of Arteriopathy (GENOA) General Research Use (GRU) 0 0 phs000392.v1.p1 Exome Sequencing of arPEO General Research Use (GRU) 1 1 SSTR phs000404.v1.p1 The Genetic Architecture of Smoking and Smoking Cessation General Research Use (GRU) 1527 1525 SSTR phs000405.v1.p1 Next Generation Mendelian Genetics: Malignant Hyperthermia General Research Use (GRU) 13 13 SSTR phs000422.v1.p1 NHLBI GO-ESP: Lung Cohorts Exome Sequencing Project (Asthma) General Research Use (GRU) 191 191 SSTR phs000435.v3.p1 Whole Exome Sequencing of Chronic Lymphocytic Leukemia General Research Use (GRU) 186 959 SSTR phs000442.v1.p1 Drug Resistant Hypertension in African Americans' Exome General Research Use (GRU) 91 91 SSTR phs000447.v1.p1 Prostate Cancer Genome Sequencing Project General Research Use (GRU) 27 90 SSTR phs000452.v3.p1 Melanoma Genome Sequencing Project General Research Use (GRU) 50 195 SSTR phs000455.v1.p1 Dobyns DBD General Research Use (GRU) 10 10 SSTR phs000475.v1.p1 The Molecular Basis of Inherited Reproductive Disorders General Research Use (GRU) 1 1 SSTR phs000479.v1.p1 NHLBI Exome Sequencing in SCID General Research Use (GRU) 3 3 SSTR phs000481.v3.p2 Cholesterol and Pharmacogenetics (CAP) Study General Research Use (GRU) 762 1615 SSTR phs000488.v2.p1 Genomic Sequencing of Lung Adenocarcinoma General Research Use (GRU) 31 62 SSTR phs000500.v1.p1 Non-Invasive Whole Genome Sequencing of a Human Fetus General Research Use (GRU) 6 8 SSTR phs000509.v1.p1 Genome Sequencing of Hepatocellular Carcinoma General Research Use (GRU) 100 178 SSTR phs000514.v1.p1 Identification of Genes Involved in Familial Coronary Artery Disease General Research Use (GRU) 19 19 SSTR phs000516.v2.p1 Genome Sequencing of Pancreatic Ductal Adenocarcinoma General Research Use (GRU) 59 118 SSTR phs000518.v1.p1 NHLBI GO-ESP Family Studies: Idiopathic Bronchiectasis General Research Use (GRU) 24 24 SSTR phs000536.v2.p1 Retrotransposition in Colorectal Cancer General Research Use (GRU) 92 17 SSTR phs000537.v1.p1 Next Generation Mendelian Genetics: Familial Hemophagocytic Lymphohistiocytosis General Research Use (GRU) 4 4 SSTR phs000539.v1.p1 Next Generation Mendelian Genetics: Congenital Hyperinsulinism General Research Use (GRU) 8 8 SSTR phs000542.v1.p1 Next Generation Mendelian Genetics: Neonatal Diabetes General Research Use (GRU) 4 4 SSTR phs000553.v1.p1 Familial Exome Sequencing in Rare Pediatric Phenotypes General Research Use (MDS) (GRU-MDS) 6 7 SSTR phs000584.v1.p1 The Longevity Genes Project General Research Use (GRU) 2140 2187 SSTR phs000609.v1.p1 RNA-Seq Studies of Gene Expression in Cells and Networks in FI and ACC in Autism General Research Use (GRU) 27 43 SSTR phs000620.v1.p1 Minnesota Center for Twin and Family Research (MCTFR) General Research Use (GRU) 6784 6097 SSTR phs000623.v1.p1 Rare Mendelian Disease in Old Order Amish and Mennonite Patients General Research Use (GRU) 106 106 SSTR phs000636.v1.p1 Whole Exome Sequencing for Familial Intracranial Aneurysm (FIA I-II) Study General Research Use (GRU) 45 44 SSTR phs000647.v1.p1 Study of Adaptation to Hypoxia in Ethiopian Highlanders General Research Use (GRU) 13 13 SSTR phs000655.v3.p1 Genetics of Inherited Muscle Disease General Research Use (GRU) 420 456 SSTR phs000659.v1.p1 Mount Sinai Hospital (MSH, Toronto, CANADA) pelvic pouch microbiome study General Research Use (GRU) 80 158 SSTR phs000660.v1.p1 Chinese Alternating Hemiplegia of Childhood (AHC) Disease Study General Research Use (GRU) 12 12 SSTR phs000664.v1.p1 Genome Variations Among the Aboriginals in Malaysia General Research Use (GRU) 34 34 SSTR phs000678.v1.p1 A Family-Based Study of Genes and Environment in Young-Onset Breast Cancer General Research Use (GRU) 3342 3416 SSTR phs000690.v1.p1 Whole-genome sequencing in multiplex epilepsy families General Research Use (GRU) 46 46 SSTR phs000691.v2.p1 CIP: Differential Response to Hydroxyurea and Incidence of Stroke in Sickle Cell Disease General Research Use (GRU) 651 651 SSTR phs000693.v6.p2 University of Washington Center for Mendelian Genomics (UW-CMG) General Research Use (GRU) 0 0 phs000715.v1.p1 NINDS MS and ADEM Deep Sequencing Studies General Research Use (GRU) 35 35 SSTR phs000722.v3.p2 Whole Exome Sequencing of Colorectal Cancer Patients from the Nurses' Health Study (NHS) and Health Professionals Follow-up Study (HPFS) General Research Use (GRU) 581 1182 SSTR phs000727.v1.p1 miRNA Profiles in Serum and CSF of Parkinson's and Alzheimer's Patients General Research Use (GRU) 211 395 SSTR phs000728.v1.p1 Lung Cancer Susceptibility in Smokers General Research Use (GRU) 165 165 SSTR phs000732.v1.p1 L1-seq and genome-wide SNP genotyping in a multiethnic Asian population General Research Use (GRU) 20 20 SSTR phs000734.v1.p1 Osteosarcoma Genome-Wide Association Study General Research Use (GRU) 694 717 SSTR phs000744.v5.p2 Yale Center for Mendelian Genomics (YCMG) General Research Use (GRU) 0 0 phs000745.v1.p1 RNAseq analysis of posterior cingulate astrocytes in Alzheimer's disease General Research Use (GRU) 20 20 SSTR phs000747.v2.p1 Whole Exome and Transcriptome Sequencing in Sporadic ALS General Research Use (GRU) 17 40 SSTR phs000766.v1.p1 GEI Studies - Psoriasis General Research Use (GRU) 4844 4844 SSTR phs000775.v1.p1 Joint Genome-Wide Gene Expression and GWAS Mapping in the MGS Dataset General Research Use (GRU) 798 798 SSTR phs000793.v1.p1 Paired AML Epigenetics Study on Clonality General Research Use (GRU) 18 18 SSTR phs000809.v1.p1 Autosomal recessive PGM3 mutations cause a new Congenital Disorder of Glycosylation General Research Use (GRU) 8 8 SSTR phs000811.v1.p1 Comparison of custom capture for targeted next generation DNA sequencing General Research Use (GRU) 10 16 SSTR phs000816.v2.p1 Characterization of X Chromosome Inactivation by high-throughput sequencing General Research Use (GRU) 424 511 SSTR phs000817.v1.p1 Responses to Varicella Zoster Virus Vaccination General Research Use (GRU) 8 256 SSTR phs000825.v1.p1 Whole Genome Sequencing of HUES63 and HUES64 General Research Use (GRU) 2 2 SSTR phs000827.v3.p1 N.C. Clinical Genomic Evaluation by NextGen Exome Sequencing (NCGENES) General Research Use (GRU) 592 592 SSTR phs000832.v1.p1 Sensitivity to the subjective effects of amphetamine General Research Use (GRU) 381 381 SSTR phs000833.v7.p1 Single Cell Analysis Program - Transcriptome (SCAP-T) General Research Use (GRU) 177 8200 SSTR phs000848.v1.p1 Autosomal Recessive TPP2 Mutations Cause a New Human Immunodeficiency General Research Use (GRU) 3 3 SSTR phs000853.v2.p2 Normative Aging Study (NAS) General Research Use (GRU) 777 1488 SSTR phs000864.v1.p1 Genomic Predictors of Combat Stress Vulnerability and Resilience General Research Use (GRU) 3992 3992 SSTR phs000868.v1.p1 Transcriptome Sequencing of Pediatric Neuroblastoma General Research Use (GRU) 29 29 SSTR phs000896.v1.p1 Functional Dynamics of the Elderly Gut Microbiome During Probiotic Consumption General Research Use (GRU) 12 72 SSTR phs000901.v1.p1 University of Washington CSF biomarker study for Parkinson disease General Research Use (GRU) 57 57 SSTR phs000979.v3.p2 HBCC Postmortem Psychiatric Molecular Studies General Research Use (GRU) 970 3788 SSTR phs000982.v1.p1 Genetic Analysis of Psoriasis and Psoriatic Arthritis General Research Use (GRU) 2847 2847 SSTR phs001020.v2.p1 Genomic Psychiatry Cohort (GPC) Whole Genome Sequencing and Genotyping Study General Research Use (GRU) 501 501 SSTR phs001022.v1.p1 PsychENCODE: Autism Transcriptional and Epigenetic Profiling General Research Use (GRU) 123 499 SSTR phs001039.v1.p1 International AMD Genomics Consortium - Exome Chip Experiment General Research Use (GRU) 27895 27895 SSTR phs001048.v2.p1 The FUSION Tissue Biopsy Study General Research Use (GRU) 307 2130 SSTR phs001122.v1.p1 Genome-wide Identification of Variants Affecting Early Human Brain Development General Research Use (GRU) 239 436 SSTR phs001134.v2.p1 Radiation-Related Genomic Profile of Papillary Thyroid Cancer after the Chernobyl Accident General Research Use (GRU) 440 4615 SSTR phs001135.v2.p1 Starting Treatment with Agonist Replacement Therapies (START) General Research Use (GRU) 979 978 SSTR phs001157.v1.p1 Wisconsin Longitudinal Study on Aging General Research Use (GRU) 9027 9231 SSTR phs001158.v3.p2 Human Dorsal Root Ganglion RNA Landscape Profiling for Neuropathic and Chronic Pain General Research Use (GRU) 68 117 SSTR phs001163.v1.p1 CRU-Ukrainian National Research Center for Radiation Medicine Trio Study General Research Use (GRU) 340 340 SSTR phs001164.v1.p1 The Role of Germline Mutation and Parental Age in Autism Spectrum Disorders General Research Use (GRU) 41 41 SSTR phs001172.v1.p2 NINDS Parkinson's Disease General Research Use (GRU) 2116 3582 SSTR phs001182.v2.p1 National Institute of Environmental Health (NIEHS) Sciences Study of Somatic Mutation Load in Clones of Single Human Cells General Research Use (GRU) 21 92 SSTR phs001188.v2.p1 The FUSION Study - Islet Expression and Regulation General Research Use (GRU) 106 422 SSTR phs001195.v1.p1 A Study to Assess the Cardiovascular, Cognitive, and Subjective Effects of Atomoxetine in Combination with Intravenous Methamphetamine General Research Use (GRU) 13 13 SSTR phs001197.v1.p1 Neural Systems, Inhibitory Control, and Methamphetamine Dependence General Research Use (GRU) 193 188 SSTR phs001206.v1.p1 Blepharospasm in a Multiplex African-American Pedigree General Research Use (GRU) 12 12 SSTR phs001209.v1.p1 MIDCIRS Reveals Antibody Diversification in Young Children with Malaria General Research Use (GRU) 22 80 SSTR phs001210.v1.p1 NCI Lung Cancer and Smoking Phenotypes in African-American Subjects General Research Use (GRU) 154 158 SSTR phs001213.v2.p1 Molecular Genetics of Heroin Dependence in China General Research Use (GRU) 1711 1043 SSTR phs001231.v2.p1 NeuroLINCS General Research Use (GRU) 4 39 SSTR phs001232.v5.p2 Clinical and Genetic Evaluation of Individuals with Undiagnosed Disorders through the Undiagnosed Diseases Network (UDN) General Research Use (GRU) 5138 6413 SSTR phs001245.v1.p1 Autosomal Recessive CD70 Deficiency General Research Use (GRU) 5 5 SSTR phs001266.v2.p1 Genome-Wide Analysis for Addiction Susceptibility Genes General Research Use (GRU) 1331 645 SSTR phs001284.v1.p1 NCI Waldenstrom Macroglobulinemia Genome-Wide Association Study General Research Use (GRU) 35 35 SSTR phs001299.v2.p1 Nicotine Addiction Genetics and Correlates General Research Use (GRU) 3508 2452 SSTR phs001300.v4.p1 NABEC: North American Brain Expression Consortium General Research Use (GRU) 432 2280 SSTR phs001303.v1.p1 GWAS of Sporadic and Familial Testicular Germ Cell Tumors General Research Use (GRU) 341 347 SSTR phs001322.v3.p1 NINDS Inherited Forms of Motor Neuron Disease Study General Research Use (GRU) 13 37 SSTR phs001375.v2.p1 Slim Initiative in Genomic Medicine for the Americas (SIGMA): Mexico City Diabetes Study (MCDS) General Research Use (GRU) 1036 1036 SSTR phs001377.v1.p1 Epigenetics of Cocaine and Nicotine Addiction General Research Use (GRU) 380 365 SSTR phs001385.v1.p1 Ancestry Admixture among Chileans General Research Use (GRU) 189 204 SSTR phs001388.v2.p1 Slim Initiative in Genomic Medicine for the Americas (SIGMA): Diabetes in Mexico Study (DMS) General Research Use (GRU) 3296 3296 SSTR phs001403.v1.p1 WES and CNV analysis of NF1-Associated Plexiform Neurofibromas General Research Use (GRU) 21 44 SSTR phs001404.v1.p1 Molecular Profiling of Gallbladder Cancer (MPOG) General Research Use (GRU) 158 433 SSTR phs001413.v1.p1 Large Scale Genotyping of Psychiatric Disorders General Research Use (GRU) 9603 8991 SSTR phs001438.v1.p1 Chromatin Accessibility in Developing Human Brain General Research Use (GRU) 3 37 SSTR phs001455.v1.p1 Screening Cases of Isolated Dystonia for Variants in CIZ1 General Research Use (GRU) 5795 5795 SSTR phs001463.v1.p1 Differential Transcription Start Site Usage in Brain-Related Samples General Research Use (GRU) 8 8 SSTR phs001481.v1.p1 Inherited Bone Marrow Failure Syndromes Study General Research Use (GRU) 456 456 SSTR phs001492.v1.p1 GWAS on Calcific Aortic Valve Stenosis in Quebec (QUEBEC-CAVS) General Research Use (GRU) 0 0 phs001500.v2.p1 National Cancer Institute (NCI) Primary Human Melanocyte QTL Study General Research Use (GRU) 106 106 SSTR phs001561.v1.p1 NIAID Clinical Center Genomics Opportunity (CCGO) Study General Research Use (GRU) 135 135 SSTR phs001611.v1.p1 Pancreas Cancer Organoid Profiling General Research Use (GRU) 71 188 SSTR phs001618.v1.p1 Dormant TILs and Sensitivity to Immune Checkpoint Blockers in Lung Cancer General Research Use (GRU) 36 60 SSTR phs001631.v1.p1 Genetics of Mood Disorders: Aging and Emotion Regulation Brain Circuitry in Bipolar General Research Use (GRU) 80 78 SSTR phs001648.v2.p1 Genomic Characterization of Metastatic Castration Resistant Prostate Cancer General Research Use (GRU) 101 311 SSTR phs001650.v1.p1 Genetic and Genomic Stability Across Lymphoblastoid Cell Line Expansions General Research Use (GRU) 6 129 SSTR phs001664.v1.p1 Parkinson's Disease Cognitive Genetics Consortium (PDCGC) General Research Use (GRU) 252 252 SSTR phs001700.v1.p1 Exome Sequencing of Large Multiethnic Population of Moyamoya Patients General Research Use (GRU) 124 124 SSTR phs001703.v5.p1 Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression General Research Use (GRU) 100 2091 SSTR phs001713.v1.p1 LCCC 1108 (UNCseqTM) General Research Use (GRU) 2074 3558 SSTR phs001718.v1.p1 C9ORF72 Hexanucleotide Repeat Sequence Genotyping Project General Research Use (GRU) 2095 2095 SSTR phs001739.v1.p1 Role of the Cervico-Vaginal Microbiome in Spontaneous Preterm Birth General Research Use (GRU) 539 1505 SSTR phs001742.v2.p1 Clonal Mapping of Multi-Organ Metastasis and Chemoresistance in Triple Negative Breast cancer General Research Use (GRU) 4 113 SSTR phs001750.v1.p1 Single Cell Analysis of Pulmonary Fibrosis General Research Use (GRU) 39 83 SSTR phs001761.v1.p1 Genomic Characteristics of MPNs in IR-Exposed Patients General Research Use (GRU) 155 155 SSTR phs001765.v1.p1 Genomic Characterization of Parathyroid Cancer General Research Use (GRU) 41 41 SSTR phs001796.v1.p1 Molecular and Cellular Correlates of Nerve Repair in Humans General Research Use (GRU) 78 92 SSTR phs001802.v2.p1 Genetics of Lymphatic Anomalies from CAG General Research Use (GRU) 6 6 SSTR phs001810.v2.p2 Gene-Environment Interactions in COCCaINE Use Disorder: Collaborative Case-Control Initiative in Cocaine Addiction General Research Use (GRU) 1874 1874 SSTR phs001813.v3.p1 Integrative Tissue Analysis of Men with Prostate Cancer General Research Use (GRU) 255 1624 SSTR phs001824.v1.p1 RNASeq of Plasmacytoid Dendritic Cells in Head and Neck Squamous Cell Cancer General Research Use (GRU) 7 19 SSTR phs001831.v1.p1 Elucidating Transcription Regulation by Epigenetics in Neuroblastoma General Research Use (GRU) 189 287 SSTR phs001836.v1.p1 A Single Cell Transcriptomic Analysis of Human Neocortical Development General Research Use (GRU) 4 76 SSTR phs001839.v1.p1 Deep Sequencing of 3 Cancer Cell Lines on 2 Sequencing Platforms General Research Use (GRU) 3 12 SSTR phs001840.v1.p1 Single-Cell Analysis of Human Pancreatic Ductal Adenocarcinoma General Research Use (GRU) 6 9 SSTR phs001847.v1.p1 Understanding RNA Biology and Therapeutics in Hematopoiesis and Leukemia General Research Use (GRU) 2 4 SSTR phs001867.v1.p1 Detection of Somatic Mutations In Vitro Aging Cells General Research Use (GRU) 13 25 SSTR phs001869.v1.p1 ADHD Genomic Association Study General Research Use (GRU) 1001 1001 SSTR phs001872.v1.p1 Genome Sequencing of Large, Multigenerational CEPH/Utah Families General Research Use (GRU) 599 599 SSTR phs001875.v1.p1 Determinants of Venetoclax Resistance General Research Use (GRU) 6 17 SSTR phs001884.v1.p1 Cognitive Ability and Homozygosity Study General Research Use (GRU) 354 354 SSTR phs001887.v1.p1 Single-Sperm Genome Sequencing General Research Use (GRU) 20 50 SSTR phs001889.v1.p1 Transposable Elements in FTLD-TDP and ALS-TDP General Research Use (GRU) 19 38 SSTR phs001892.v1.p1 miRNA Profiling of Maternal and Non-Maternal Healthy Adult Blood Plasma Using Small RNA-Sequencing General Research Use (GRU) 13 3 SSTR phs001899.v2.p1 NIAID Centralized Sequencing Program General Research Use (GRU) 1940 1880 SSTR phs001900.v1.p1 Genetic Control of Expression and Splicing in Developing Human Brain General Research Use (GRU) 219 1190 SSTR phs001920.v1.p1 Genomic Characterization of Brain Metastases from Lung Cancer General Research Use (GRU) 16 57 SSTR phs001932.v1.p1 RNAseq Transcriptomic Analyses of European Ancestry Samples in MGS Dataset General Research Use (GRU) 1271 2374 SSTR phs001945.v1.p1 National Institutes of Health H3Africa African Collaborative Center for Microbiome and Genomics Research (ACCME) General Research Use (GRU) 11215 11452 SSTR phs001957.v2.p1 Investigation of Human DNA Replication Timing Variation by Whole Genome Sequencing General Research Use (GRU) 54 90 SSTR phs001958.v1.p1 Cell-Type Specific Effects of Genetic Variation on Chromatin Accessibility During Human Neuronal Differentiation General Research Use (GRU) 85 222 SSTR phs001961.v2.p1 LungMAP: Molecular Atlas of Lung Development - Human Lung Tissue General Research Use (GRU) 20 30 SSTR phs001966.v1.p1 L1 Retrotransposon sequencing in Cocaine Use Disorder - Study 1 General Research Use (GRU) 51 49 SSTR phs001968.v1.p1 L1 Retrotransposon Sequencing in Schizophrenia - Study 1 General Research Use (GRU) 126 126 SSTR phs001969.v1.p1 Cellular Origins and Genetic Landscape of Cutaneous GD T Cell Lymphoma General Research Use (GRU) 20 37 SSTR phs001982.v1.p1 Rb and p53-Deficient Pleomorphic Myofibroblastic Sarcomas Require Skp2 General Research Use (GRU) 62 62 SSTR phs001992.v1.p1 Reference Haplotypes for Complement Component 4 (C4) Gene Variation General Research Use (GRU) 1149 1180 SSTR phs002016.v1.p1 MicroRNA Biomarkers for Prediction of Preeclampsia General Research Use (GRU) 212 212 SSTR phs002030.v1.p1 Impact of Mobile Element Insertions on Human Transcriptome Variation General Research Use (GRU) 638 638 SSTR phs002032.v2.p1 Genetic Neuroscience: How Human Genes and Alleles Shape Neuronal Phenotypes General Research Use (GRU) 0 0 phs002041.v2.p1 WGSPD Project 1: Whole Genome Sequencing for Schizophrenia and Bipolar Disorder General Research Use (GRU) 0 0 phs002045.v1.p1 Intraductal Transplantation Models of PDAC Reveal Progression of Subtypes General Research Use (GRU) 15 70 SSTR phs002046.v1.p1 Grady Trauma Project (GTP) General Research Use (GRU) 5585 5585 SSTR phs002056.v1.p1 Genetic Factors associated with Conversion from Active Surveillance to Treatment for Prostate Cancer General Research Use (GRU) 1413 1435 SSTR phs002066.v2.p1 Mechanisms of Extreme Genomic Instability at Large Transcribed Genes General Research Use (GRU) 2 182 SSTR phs002128.v1.p1 Identification and Molecular Characterization of Somatic Mutations in Malformations of Cortical Development General Research Use (GRU) 94 156 SSTR phs002139.v1.p1 Environmental Arsenic and Diabetes Mellitus (Chihuahua Cohort) General Research Use (GRU) 1166 0 SSTR phs002143.v1.p1 Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation General Research Use (GRU) 24 264 SSTR phs002146.v1.p1 Evolution of Chromatin Architecture and Transcriptional Regulation in Mammals General Research Use (GRU) 3 22 SSTR phs002156.v1.p1 Molecular Characterization of Hemimegalencephaly General Research Use (GRU) 52 52 SSTR phs002170.v1.p1 Genome-Wide Association Study of Patients with Coccidioidomycosis General Research Use (GRU) 0 0 phs002175.v1.p1 The NCAA-DoD Concussion Assessment, Research, and Education (CARE) Consortium General Research Use (GRU) 551 5206 SSTR phs002182.v3.p1 Asthma in the Lives of Families Today (ALOFT) General Research Use (GRU) 259 756 SSTR phs002188.v2.p1 Single Cell Genomic Analysis of Lymphoma General Research Use (GRU) 10 22 SSTR phs002197.v1.p1 Single Cell and Tissue Level Functional Genomics Analysis of Astrocyte-Related Mechanisms in Taupathy General Research Use (GRU) 16 16 SSTR phs002222.v2.p1 Transcriptomic and Clonal Characterization of T Cells in the Human Central Nervous System General Research Use (GRU) 12 46 SSTR phs002224.v1.p1 Sputum RNA-Seq from Asthmatic Patients for Microbes and Genes General Research Use (GRU) 116 116 SSTR phs002225.v3.p1 HTAN MCL Pre-Cancer Atlas Pilot Project - Targeted Sequencing Development Study General Research Use (GRU) 63 430 SSTR phs002229.v1.p1 Germ Cell Tumor Molecular Heterogeneity Revealed through Analysis of Primary and Metastasis Pairs General Research Use (GRU) 10 30 SSTR phs002262.v2.p1 Characterization of High-Grade Serous Ovarian Cancer Subtypes via Single-Cell Profiling General Research Use (GRU) 13 37 SSTR phs002269.v1.p1 A New Pipeline to Predict and Confirm Tumor Neoantigens Predicts Better Response to Checkpoint Blockade General Research Use (GRU) 37 37 SSTR phs002270.v1.p1 Very Low Tumor Mutation Burden Identifies Inflamed Recurrent Glioblastomas Responsive to Cancer Immunotherapy General Research Use (GRU) 34 82 SSTR phs002272.v1.p1 HuBMAP: Single-Cell Data from Human Tissues General Research Use (GRU) 11 187 SSTR phs002279.v1.p1 DNA and RNA Sequencing of Single Human Haploid Germ Cells General Research Use (GRU) 2 540 SSTR phs002280.v1.p1 Multimodal Analysis for Human Ex Vivo Studies Shows Extensive Molecular Changes from Delays in Blood Processing General Research Use (GRU) 11 55 SSTR phs002287.v1.p1 Evolution of Resistance in ER+ Breast Cancer General Research Use (GRU) 24 72 SSTR phs002291.v1.p1 Whole Transcriptome Sequencing of Human Tumor Cells and Hematopoietic Stem and Progenitor Cells During Aging and Bone Marrow Disorders General Research Use (GRU) 5 10 SSTR phs002292.v1.p1 Functional Enhancer Elements Drive Subclass-Selective Expression From Mouse to Human Neocortex General Research Use (GRU) 3 318 SSTR phs002294.v1.p1 Evolution of Core Archetypal Phenotypes in High-Grade Serous Ovarian Cancer (HGSOC) General Research Use (GRU) 23 72 SSTR phs002295.v1.p1 Cross-site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms of CIMAC-CIDC Network General Research Use (GRU) 8 234 SSTR phs002297.v2.p1 The Immune Microenvironment Shapes Transcriptional and Genetic Heterogeneity in Chronic Lymphocytic Leukemia General Research Use (GRU) 21 57 SSTR phs002315.v1.p1 Integrated Analysis of Multimodal Single-Cell Data General Research Use (GRU) 9 1 SSTR phs002316.v1.p1 Simultaneous Trimodal Single Cell Measurement of Transcripts, Epitopes, and Chromatin Accessibility Using TEA-Seq General Research Use (GRU) 6 34 SSTR phs002319.v1.p1 International Verapamil SR/Trandolapril [INVEST] Genes Study General Research Use (GRU) 1529 1529 SSTR phs002333.v1.p1 Massively Parallel Single-Cell RNA-Sequencing of Chronic Rhinosinusitis Nasal and Sinus Tissue General Research Use (GRU) 8 12 SSTR phs002340.v1.p1 A Multi-Omic Single-Cell Atlas of Human Gynecological Malignancies General Research Use (GRU) 11 22 SSTR phs002342.v1.p1 Optimized Polyepitope Neoantigen DNA Vaccines Elicit Neoantigen-Specific Immune Responses in Preclinical Models and in Clinical Translation General Research Use (GRU) 1 5 SSTR phs002347.v1.p1 PDAC Prognosis Biomarkers in Genomic and Transcriptomic Molecular Data General Research Use (GRU) 150 450 SSTR phs002368.v1.p1 CaBagE: a Cas9-Based Background Elimination Strategy for Targeted, Long-Read DNA Sequencing General Research Use (GRU) 2 4 SSTR phs002378.v1.p1 CSER: Evaluating Utility and Improving Implementation of Genomic Sequencing for Pediatric Cancer Patients in the Diverse Population and Healthcare Settings of Texas: The KidsCanSeq Study General Research Use (GRU) 0 0 phs002388.v1.p1 Genomic and Transcriptomic Markers Associated with Response to Immune Checkpoint Blockade General Research Use (GRU) 52 199 SSTR phs002391.v1.p1 De Novo Mutation Rates at the Single-Mutation Resolution in the Human Genome General Research Use (GRU) 13 26 SSTR phs002396.v1.p1 Integrated Metabolic Profiling and Gene Expression Analysis Reveals Therapeutic Modalities in Breast Cancer General Research Use (GRU) 26 40 SSTR phs002400.v1.p1 The Role of Myeloid Cells in Parkinson's Disease General Research Use (GRU) 285 358 SSTR phs002401.v1.p1 High Glucose Macrophage Exosomes Enhance Atherosclerosis by Driving Cellular Proliferation and Hematopoiesis General Research Use (GRU) 26 26 SSTR phs002405.v1.p1 Gene Variants in Pheochromocytoma and Paraganglioma General Research Use (GRU) 16 23 SSTR phs002407.v1.p1 A Single Cell Atlas of MMRd and MMRp Colorectal Cancer General Research Use (GRU) 62 181 SSTR phs002416.v2.p1 Characterization of CNS Metastases General Research Use (GRU) 46 71 SSTR phs002443.v1.p1 Molecular Signatures of DCIS to Invasive Progression for Basal-Like Breast Cancers: An Integrated Mouse Model and Human Tumor Study General Research Use (GRU) 11 18 SSTR phs002449.v1.p1 Tissue and Fluid Analysis in Ocular Inflammatory Disease General Research Use (GRU) 4 8 SSTR phs002463.v1.p1 Natural Genetic Variation in the Human Genome General Research Use (GRU) 628 628 SSTR phs002465.v1.p1 The Human Pancreas Analysis Program (HPAP) General Research Use (GRU) 80 159 SSTR phs002487.v1.p1 Epigenomes and Transcriptomes of Brain Samples of Schizophrenics and Controls General Research Use (GRU) 58 700 SSTR phs002502.v2.p1 Center for Common Disease Genomics [CCDG] Neuropsychiatric: Autism Spectrum Disorder (ASD) – Whole Exomes General Research Use (GRU) 0 0 phs002515.v1.p1 Mutational Landscape of MCPyV-Positive and MCPyV-Negative Merkel Cell Carcinomas General Research Use (GRU) 49 98 SSTR phs002541.v1.p1 Integrated Genomic and Transcriptomic Analysis of Small Cell Lung Cancer Reveals Inter- and Intratumoral Heterogeneity and a Novel Chemotherapy-Refractory Subtype General Research Use (GRU) 72 168 SSTR phs002552.v1.p1 Genomic Analysis of Low Grade B-Cell Lymphoma General Research Use (GRU) 64 183 SSTR phs002554.v2.p1 Gene Expression and Epigenetic Analyses of Human Myocytes From Different Muscles General Research Use (GRU) 11 172 SSTR phs002610.v2.p1 Maintenance of Genome Sequence Integrity in Long- and Short-lived Rodent Species General Research Use (GRU) 3 39 SSTR phs002612.v1.p1 Immunogenomics of Malignant Brain Tumors General Research Use (GRU) 30 203 SSTR phs002623.v1.p1 Whole Genome Sequencing of Bilateral Cleft Lip and Palate Families from Africa: CIDR General Research Use (GRU) 804 804 SSTR phs002625.v1.p1 The Spatio-Temporal Evolution of Multiple Myeloma from Baseline to Relapse-Refractory States General Research Use (GRU) 25 179 SSTR phs002652.v1.p1 Identification of Somatic Changes in Tumors from Fanconi Anemia Patients General Research Use (GRU) 46 137 SSTR phs002728.v1.p1 RNA-Seq of PBMC's from rUTI Patients and Healthy Controls General Research Use (GRU) 30 48 SSTR phs002735.v1.p1 Tumor Infiltrating Lymphocytes (TIL) Recognize Unique Somatic Mutations and Mediate Objective Clinical Responses in Metastatic Breast Cancer General Research Use (GRU) 42 358 SSTR phs002748.v1.p1 Transcriptome and TCR Sequencing of T Cells from Metastectomies General Research Use (GRU) 15 123 SSTR phs002756.v1.p1 Characterizing the Role of the Immune Microenvironment in Multiple Myeloma Progression at a Single Cell Level General Research Use (GRU) 20 20 SSTR phs002764.v1.p1 Dissecting Cell Composition and Drug Sensitivity in Human Adenoid Cystic Carcinomas (ACCs) General Research Use (GRU) 7 25 SSTR phs002766.v1.p1 Generation of a Cellular Atlas of Human Adipose Tissue General Research Use (GRU) 65 176 SSTR phs002767.v1.p1 Epidemiologic Architecture for Genes Linked to Environment (EAGLE) MetaboChip Study General Research Use (GRU) 13881 13881 SSTR phs002792.v1.p1 Characterization of Neoantigen-reactive T cells by Single-Cell Analysis General Research Use (GRU) 4 48 SSTR phs002812.v1.p1 Multiplexed scRNA-Seq Reveals Cellular and Genetic Correlates of SLE General Research Use (GRU) 258 258 SSTR phs002817.v1.p1 Mutations in GNAI2 Cause Developmental Abnormalities and Immune Dysregulation General Research Use (GRU) 23 23 SSTR phs002845.v1.p1 Expression of Activation Induced Cytidine Deaminase and Risk of Transformation in Follicular Lymphoma General Research Use (GRU) 199 199 SSTR phs002861.v1.p1 Genomic Data Archive From the Network for Pancreatic Organ Donors With Diabetes General Research Use (GRU) 412 412 SSTR phs002876.v1.p1 CTN - 0051: Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment (X:BOT) General Research Use (GRU) 638 615 SSTR phs002881.v1.p1 The Pathogenesis and Genetics of Disseminated Coccidioidomycosis General Research Use (GRU) 67 67 SSTR phs002903.v1.p1 The Role of CDX2 in Controlling ABCB1 Expression and Chemosensitivity in Human Colon Cancer General Research Use (GRU) 2 12 SSTR phs002928.v1.p1 Adoptive Cell Therapy of Autologous T cell Receptor-Engineered T Cells Targeting the p53 Neoantigens in Human Solid Tumors General Research Use (GRU) 23 194 SSTR phs002935.v1.p1 Transcriptomic Profiling of Oropharyngeal Squamous Cell Carcinoma General Research Use (GRU) 133 133 SSTR phs002960.v1.p1 Exploring the Microbiome-Gut-Brain Axis with Respect to Psychoneurological Symptoms for Children with Solid Tumors General Research Use (GRU) 44 57 SSTR phs002986.v1.p1 A Randomized Multi-Institutional Phase II Trial of Everolimus as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck General Research Use (GRU) 42 42 SSTR phs002989.v1.p1 Genomic Analysis of Follicular Lymphoma General Research Use (GRU) 117 430 SSTR phs002991.v1.p1 Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation General Research Use (GRU) 11 51 SSTR phs002998.v1.p1 Immune Profiles Study General Research Use (GRU) 135 135 SSTR phs003003.v1.p1 Gene Expression between PMD and Control LCLs at Baseline, E2, and E2 Withdrawal General Research Use (GRU) 17 51 SSTR phs003042.v1.p1 Novel Strategies to Eliminate Resistance to B-cell Receptor Inhibitor Therapy in Lymphoid Malignancies General Research Use (GRU) 38 216 SSTR phs003059.v1.p1 Metastatic Colorectal Adenocarcinoma Tumor Purity Assessment from Whole Exome Sequencing Data General Research Use (GRU) 18 30 SSTR phs003062.v1.p1 De Novo Characterization of Cell-Free DNA Fragmentation Hotspots in Plasma Whole-Genome Sequencing General Research Use (GRU) 66 66 SSTR phs003064.v1.p1 Phenotypic Signatures of Circulating Neoantigen-Reactive CD8+ T Cells in Patients with Metastatic Cancers General Research Use (GRU) 9 29 SSTR phs003065.v1.p1 Uncovering RNA Signatures of C9orf72-Linked ALS and Related Disorders General Research Use (GRU) 193 193 SSTR phs003067.v1.p1 Using NGS to Sequence Whole Genomes to Identify Genes Underlying ALS General Research Use (GRU) 1677 1677 SSTR phs003071.v1.p1 POISED (Peanut Oral Immunotherapy: Safety, Efficacy, and Discovery) General Research Use (GRU) 118 118 SSTR phs003072.v1.p1 RNA-Seq of Whole Blood from Patients with Intracranial Aneurysms General Research Use (GRU) 43 43 SSTR phs003075.v1.p1 Longitudinal Studies of Patients with Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM) General Research Use (GRU) 77 229 SSTR phs003109.v1.p1 Oral Immunotherapy for Induction of Tolerance and Desensitization in Peanut-Allergic Children (IMPACT) General Research Use (GRU) 31 31 SSTR phs003122.v1.p1 Human Blastocyst 10X Single Cell RNA Sequencing General Research Use (GRU) 58 7 SSTR phs003143.v1.p1 My Pediatric and Adult Rare Tumor (MyPART) Natural History Study of Rare Solid Tumors General Research Use (GRU) 497 192 SSTR phs003152.v1.p1 CPTAC: Proteogenomic Studies of Ovarian Tumor Responses to Agents Targeting the DNA Damage Response General Research Use (GRU) 148 156 SSTR phs003156.v1.p1 Developing Biomarkers Incorporating High Throughput RNA, DNA, Small RNA Sequencing and Protein Expression in Inflammatory Bowel Disease Using Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue Samples General Research Use (GRU) 119 201 SSTR phs003158.v1.p1 Sézary Syndrome Originates from Heavily Mutated Hematopoietic Progenitors General Research Use (GRU) 4 23 SSTR phs003165.v1.p1 Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases General Research Use (GRU) 12 69 SSTR phs003166.v1.p1 Enhancing Open Data Sharing for Functional Genomics Experiments: Measures to Quantify Genomic Information Leakage and File Formats for Privacy Preservation General Research Use (GRU) 3 3 SSTR phs003169.v1.p1 Extracellular microRNA Biomarkers for Diagnostic and Prognostic Assessment of Preeclampsia at Triage General Research Use (GRU) 123 123 SSTR phs003177.v1.p1 Comparison Between qPCR and RNA-Seq Reveals Challenges of Quantifying HLA Expression General Research Use (GRU) 96 125 SSTR phs003179.v1.p1 Rheumatoid Arthritis Finger Stick RNA Sequence Data General Research Use (GRU) 5 355 SSTR phs003182.v1.p1 Reference Profiles of ExRNAs in Normal Human Pregnancy General Research Use (GRU) 110 1020 SSTR phs003190.v1.p1 Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and is Associated with Worse Outcomes General Research Use (GRU) 5 23 SSTR phs003196.v1.p1 Detection and Targeting of Splicing Deregulation in Pediatric Acute Myeloid Leukemia Stem Cells General Research Use (GRU) 21 36 SSTR phs003197.v1.p1 Genetic Study of Vascular Anomalies General Research Use (GRU) 154 154 SSTR phs003230.v1.p1 Temporal Evolution Reveals Bifurcated Lineages in Aggressive Neuroendocrine Small Cell Prostate Cancer Trans-Differentiation General Research Use (GRU) 11 66 SSTR phs003231.v1.p1 ApoA-1 and Atherosclerosis in Psoriasis General Research Use (GRU) 310 310 SSTR phs003242.v1.p1 TREM2+ Cells in Human Basal Cell Carcinomas General Research Use (GRU) 2 2 SSTR phs003243.v1.p1 Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biologic Studies (10C0086) General Research Use (GRU) 12 66 SSTR phs003245.v1.p1 Phenotyping and Therapeutic Approaches for Patients with Sellar/Suprasellar Disorders General Research Use (GRU) 4 3 SSTR phs003250.v1.p1 Therapeutic Genetics and Disease Modeling in LAMA2-CMD General Research Use (GRU) 5 7 SSTR phs003257.v1.p1 Investigating the Role of Neddylation in the Repair of Topoisomerase I-Mediated DNA Damage in Colorectal Cancer General Research Use (GRU) 3 3 SSTR phs003261.v1.p1 Studies in the Pathogenesis of Systemic Capillary Leak Syndrome (SCLS, Clarkson Disease) General Research Use (GRU) 70 70 SSTR phs003269.v1.p1 GATA2 Deficiency and the MonoMAC Syndrome General Research Use (GRU) 6 6 SSTR phs003277.v1.p1 Cellular Indexing of Transcriptomes and Epitopes Sequencing (CITE-Seq) Analysis to Investigate the Impact of Granulocyte-Colony Stimulating Factor on CRISPR/Cas9 Gene Edited Human Hematopoietic Stem Cell Function General Research Use (GRU) 1 6 SSTR phs003319.v1.p1 Interruption of BTK Inhibitor Improves Response to SARS-CoV-2 Booster Vaccination in Patients with Chronic Lymphocytic Leukemia General Research Use (GRU) 81 0 SSTR - Authorized Data Access Requests