Name: rs4605857
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs4605857

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr6:162144686 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: T>C
Variation Type: SNV Single Nucleotide Variation
Frequency: T=0.489550 (129579/264690, TOPMED)
C=0.449485 (92877/206630, ALFA)
T=0.494341 (69186/139956, GnomAD) (+ 19 more)
C=0.27691 (7825/28258, 14KJPN)
C=0.27721 (4646/16760, 8.3KJPN)
C=0.4705 (3013/6404, 1000G_30x)
C=0.4593 (2300/5008, 1000G)
C=0.3690 (1653/4480, Estonian)
C=0.4520 (1742/3854, ALSPAC)
C=0.4401 (1632/3708, TWINSUK)
C=0.2505 (734/2930, KOREAN)
C=0.4419 (921/2084, HGDP_Stanford)
C=0.4196 (475/1132, Daghestan)
C=0.463 (462/998, GoNL)
C=0.475 (285/600, NorthernSweden)
T=0.328 (113/344, SGDP_PRJ)
T=0.403 (87/216, Qatari)
C=0.283 (60/212, Vietnamese)
T=0.50 (30/60, Ancient Sardinia)
C=0.50 (30/60, Ancient Sardinia)
C=0.40 (16/40, GENOME_DK)
T=0.39 (11/28, Siberian)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: PRKN : Intron Variant
Publications: 0 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	206724	T=0.550517	C=0.449483
European	Sub	180660	T=0.561032	C=0.438968
African	Sub	9726	T=0.3231	C=0.6769
African Others	Sub	348	T=0.253	C=0.747
African American	Sub	9378	T=0.3257	C=0.6743
Asian	Sub	704	T=0.706	C=0.294
East Asian	Sub	558	T=0.717	C=0.283
Other Asian	Sub	146	T=0.664	C=0.336
Latin American 1	Sub	784	T=0.500	C=0.500
Latin American 2	Sub	2836	T=0.5737	C=0.4263
South Asian	Sub	5036	T=0.5888	C=0.4112
Other	Sub	6978	T=0.5483	C=0.4517

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	T=0.489550	C=0.510450
Allele Frequency Aggregator	Total	Global	206630	T=0.550515	C=0.449485
Allele Frequency Aggregator	European	Sub	180584	T=0.561041	C=0.438959
Allele Frequency Aggregator	African	Sub	9726	T=0.3231	C=0.6769
Allele Frequency Aggregator	Other	Sub	6960	T=0.5481	C=0.4519
Allele Frequency Aggregator	South Asian	Sub	5036	T=0.5888	C=0.4112
Allele Frequency Aggregator	Latin American 2	Sub	2836	T=0.5737	C=0.4263
Allele Frequency Aggregator	Latin American 1	Sub	784	T=0.500	C=0.500
Allele Frequency Aggregator	Asian	Sub	704	T=0.706	C=0.294
gnomAD - Genomes	Global	Study-wide	139956	T=0.494341	C=0.505659
gnomAD - Genomes	European	Sub	75818	T=0.57221	C=0.42779
gnomAD - Genomes	African	Sub	41930	T=0.31770	C=0.68230
gnomAD - Genomes	American	Sub	13614	T=0.52446	C=0.47554
gnomAD - Genomes	Ashkenazi Jewish	Sub	3322	T=0.6017	C=0.3983
gnomAD - Genomes	East Asian	Sub	3122	T=0.7332	C=0.2668
gnomAD - Genomes	Other	Sub	2150	T=0.4898	C=0.5102
14KJPN	JAPANESE	Study-wide	28258	T=0.72309	C=0.27691
8.3KJPN	JAPANESE	Study-wide	16760	T=0.72279	C=0.27721
1000Genomes_30x	Global	Study-wide	6404	T=0.5295	C=0.4705
1000Genomes_30x	African	Sub	1786	T=0.2867	C=0.7133
1000Genomes_30x	Europe	Sub	1266	T=0.5695	C=0.4305
1000Genomes_30x	South Asian	Sub	1202	T=0.6190	C=0.3810
1000Genomes_30x	East Asian	Sub	1170	T=0.7368	C=0.2632
1000Genomes_30x	American	Sub	980	T=0.563	C=0.437
1000Genomes	Global	Study-wide	5008	T=0.5407	C=0.4593
1000Genomes	African	Sub	1322	T=0.2874	C=0.7126
1000Genomes	East Asian	Sub	1008	T=0.7421	C=0.2579
1000Genomes	Europe	Sub	1006	T=0.5726	C=0.4274
1000Genomes	South Asian	Sub	978	T=0.633	C=0.367
1000Genomes	American	Sub	694	T=0.555	C=0.445
Genetic variation in the Estonian population	Estonian	Study-wide	4480	T=0.6310	C=0.3690
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.5480	C=0.4520
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.5599	C=0.4401
KOREAN population from KRGDB	KOREAN	Study-wide	2930	T=0.7495	C=0.2505
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	T=0.5581	C=0.4419
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	T=0.757	C=0.243
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	T=0.582	C=0.418
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	T=0.431	C=0.569
HGDP-CEPH-db Supplement 1	Europe	Sub	320	T=0.572	C=0.428
HGDP-CEPH-db Supplement 1	Africa	Sub	242	T=0.256	C=0.744
HGDP-CEPH-db Supplement 1	America	Sub	216	T=0.514	C=0.486
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	T=0.82	C=0.18
Genome-wide autozygosity in Daghestan	Global	Study-wide	1132	T=0.5804	C=0.4196
Genome-wide autozygosity in Daghestan	Daghestan	Sub	628	T=0.576	C=0.424
Genome-wide autozygosity in Daghestan	Near_East	Sub	144	T=0.535	C=0.465
Genome-wide autozygosity in Daghestan	Central Asia	Sub	122	T=0.639	C=0.361
Genome-wide autozygosity in Daghestan	Europe	Sub	108	T=0.528	C=0.472
Genome-wide autozygosity in Daghestan	South Asian	Sub	94	T=0.71	C=0.29
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	T=0.44	C=0.56
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	T=0.537	C=0.463
Northern Sweden	ACPOP	Study-wide	600	T=0.525	C=0.475
SGDP_PRJ	Global	Study-wide	344	T=0.328	C=0.672
Qatari	Global	Study-wide	216	T=0.403	C=0.597
A Vietnamese Genetic Variation Database	Global	Study-wide	212	T=0.717	C=0.283
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	60	T=0.50	C=0.50
The Danish reference pan genome	Danish	Study-wide	40	T=0.60	C=0.40
Siberian	Global	Study-wide	28	T=0.39	C=0.61

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 6	NC_000006.12:g.162144686T>C
GRCh37.p13 chr 6	NC_000006.11:g.162565718T>C
PRKN RefSeqGene	NG_008289.2:g.588117A>G

Gene: PRKN, parkin RBR E3 ubiquitin protein ligase (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PRKN transcript variant 1	NM_004562.3:c.534+56445A>G	N/A	Intron Variant
PRKN transcript variant 2	NM_013987.3:c.534+56445A>G	N/A	Intron Variant
PRKN transcript variant 3	NM_013988.3:c.172-171269A… NM_013988.3:c.172-171269A>G	N/A	Intron Variant
PRKN transcript variant X2	XM_011535863.2:c.531+5644… XM_011535863.2:c.531+56445A>G	N/A	Intron Variant
PRKN transcript variant X1	XM_017010908.2:c.648+5644… XM_017010908.2:c.648+56445A>G	N/A	Intron Variant
PRKN transcript variant X3	XM_024446449.2:c.297+5644… XM_024446449.2:c.297+56445A>G	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	T=	C
GRCh38.p14 chr 6	NC_000006.12:g.162144686=	NC_000006.12:g.162144686T>C
GRCh37.p13 chr 6	NC_000006.11:g.162565718=	NC_000006.11:g.162565718T>C
PRKN RefSeqGene	NG_008289.2:g.588117=	NG_008289.2:g.588117A>G
PRKN transcript variant 1	NM_004562.2:c.534+56445=	NM_004562.2:c.534+56445A>G
PRKN transcript variant 1	NM_004562.3:c.534+56445=	NM_004562.3:c.534+56445A>G
PRKN transcript variant 2	NM_013987.2:c.534+56445=	NM_013987.2:c.534+56445A>G
PRKN transcript variant 2	NM_013987.3:c.534+56445=	NM_013987.3:c.534+56445A>G
PRKN transcript variant 3	NM_013988.2:c.172-171269=	NM_013988.2:c.172-171269A>G
PRKN transcript variant 3	NM_013988.3:c.172-171269=	NM_013988.3:c.172-171269A>G
PARK2 transcript variant X1	XM_005267004.1:c.534+56445=	XM_005267004.1:c.534+56445A>G
PRKN transcript variant X2	XM_011535863.2:c.531+56445=	XM_011535863.2:c.531+56445A>G
PRKN transcript variant X1	XM_017010908.2:c.648+56445=	XM_017010908.2:c.648+56445A>G
PRKN transcript variant X3	XM_024446449.2:c.297+56445=	XM_024446449.2:c.297+56445A>G

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

129 SubSNP, 21 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	SC_JCM	ss6242731	Feb 20, 2003 (111)
2	PERLEGEN	ss24716566	Sep 20, 2004 (123)
3	ABI	ss44691747	Mar 14, 2006 (126)
4	ILLUMINA	ss66618912	Nov 30, 2006 (127)
5	ILLUMINA	ss67349605	Nov 30, 2006 (127)
6	ILLUMINA	ss67741422	Nov 30, 2006 (127)
7	CSHL-HAPMAP	ss68396807	Jan 12, 2007 (127)
8	ILLUMINA	ss70811322	May 24, 2008 (130)
9	ILLUMINA	ss71391587	May 17, 2007 (127)
10	ILLUMINA	ss75446598	Dec 06, 2007 (129)
11	ILLUMINA	ss79186665	Dec 15, 2007 (130)
12	HGSV	ss82527233	Dec 15, 2007 (130)
13	KRIBB_YJKIM	ss84297741	Dec 15, 2007 (130)
14	BCMHGSC_JDW	ss93596572	Mar 24, 2008 (129)
15	HUMANGENOME_JCVI	ss98558711	Feb 04, 2009 (130)
16	BGI	ss104381412	Dec 01, 2009 (131)
17	1000GENOMES	ss111245127	Jan 25, 2009 (130)
18	1000GENOMES	ss115423743	Jan 25, 2009 (130)
19	ILLUMINA-UK	ss116803756	Feb 14, 2009 (130)
20	ILLUMINA	ss122337232	Dec 01, 2009 (131)
21	ENSEMBL	ss142480729	Dec 01, 2009 (131)
22	ENSEMBL	ss142882687	Dec 01, 2009 (131)
23	ILLUMINA	ss154302242	Dec 01, 2009 (131)
24	GMI	ss157844007	Dec 01, 2009 (131)
25	ILLUMINA	ss159479085	Dec 01, 2009 (131)
26	ILLUMINA	ss160690712	Dec 01, 2009 (131)
27	COMPLETE_GENOMICS	ss162967060	Jul 04, 2010 (132)
28	COMPLETE_GENOMICS	ss165133167	Jul 04, 2010 (132)
29	COMPLETE_GENOMICS	ss167458677	Jul 04, 2010 (132)
30	ILLUMINA	ss171834841	Jul 04, 2010 (132)
31	ILLUMINA	ss173760208	Jul 04, 2010 (132)
32	BUSHMAN	ss202704050	Jul 04, 2010 (132)
33	BCM-HGSC-SUB	ss207389659	Jul 04, 2010 (132)
34	1000GENOMES	ss222803867	Jul 14, 2010 (132)
35	1000GENOMES	ss233774166	Jul 15, 2010 (132)
36	1000GENOMES	ss240769999	Jul 15, 2010 (132)
37	BL	ss254791372	May 09, 2011 (134)
38	GMI	ss279110760	May 04, 2012 (137)
39	PJP	ss293778470	May 09, 2011 (134)
40	ILLUMINA	ss480979083	May 04, 2012 (137)
41	ILLUMINA	ss480999551	May 04, 2012 (137)
42	ILLUMINA	ss481976932	Sep 08, 2015 (146)
43	ILLUMINA	ss485284450	May 04, 2012 (137)
44	ILLUMINA	ss537249218	Sep 08, 2015 (146)
45	TISHKOFF	ss559679047	Apr 25, 2013 (138)
46	SSMP	ss654021679	Apr 25, 2013 (138)
47	ILLUMINA	ss778911888	Aug 21, 2014 (142)
48	ILLUMINA	ss783088138	Aug 21, 2014 (142)
49	ILLUMINA	ss784045610	Aug 21, 2014 (142)
50	ILLUMINA	ss825517183	Apr 01, 2015 (144)
51	ILLUMINA	ss832346579	Apr 01, 2015 (144)
52	ILLUMINA	ss832990529	Aug 21, 2014 (142)
53	ILLUMINA	ss833581358	Aug 21, 2014 (142)
54	ILLUMINA	ss834373241	Aug 21, 2014 (142)
55	EVA-GONL	ss983745066	Aug 21, 2014 (142)
56	JMKIDD_LAB	ss1074219380	Aug 21, 2014 (142)
57	1000GENOMES	ss1323202793	Aug 21, 2014 (142)
58	HAMMER_LAB	ss1397478825	Sep 08, 2015 (146)
59	DDI	ss1430964376	Apr 01, 2015 (144)
60	EVA_GENOME_DK	ss1581990506	Apr 01, 2015 (144)
61	EVA_DECODE	ss1593321346	Apr 01, 2015 (144)
62	EVA_UK10K_ALSPAC	ss1617199456	Apr 01, 2015 (144)
63	EVA_UK10K_TWINSUK	ss1660193489	Apr 01, 2015 (144)
64	EVA_SVP	ss1712918176	Apr 01, 2015 (144)
65	ILLUMINA	ss1752613948	Sep 08, 2015 (146)
66	HAMMER_LAB	ss1804778802	Sep 08, 2015 (146)
67	WEILL_CORNELL_DGM	ss1926986902	Feb 12, 2016 (147)
68	GENOMED	ss1970579207	Jul 19, 2016 (147)
69	JJLAB	ss2024160209	Sep 14, 2016 (149)
70	USC_VALOUEV	ss2152354112	Dec 20, 2016 (150)
71	HUMAN_LONGEVITY	ss2290312646	Dec 20, 2016 (150)
72	SYSTEMSBIOZJU	ss2626570179	Nov 08, 2017 (151)
73	ILLUMINA	ss2634541838	Nov 08, 2017 (151)
74	GRF	ss2707993654	Nov 08, 2017 (151)
75	GNOMAD	ss2847740064	Nov 08, 2017 (151)
76	AFFY	ss2985394691	Nov 08, 2017 (151)
77	AFFY	ss2986024003	Nov 08, 2017 (151)
78	SWEGEN	ss3000322213	Nov 08, 2017 (151)
79	BIOINF_KMB_FNS_UNIBA	ss3025871644	Nov 08, 2017 (151)
80	CSHL	ss3347336308	Nov 08, 2017 (151)
81	ILLUMINA	ss3629709913	Oct 12, 2018 (152)
82	ILLUMINA	ss3632453329	Oct 12, 2018 (152)
83	ILLUMINA	ss3633446114	Oct 12, 2018 (152)
84	ILLUMINA	ss3634170094	Oct 12, 2018 (152)
85	ILLUMINA	ss3635099724	Oct 12, 2018 (152)
86	ILLUMINA	ss3635850337	Oct 12, 2018 (152)
87	ILLUMINA	ss3636828814	Oct 12, 2018 (152)
88	ILLUMINA	ss3637603245	Oct 12, 2018 (152)
89	ILLUMINA	ss3638670632	Oct 12, 2018 (152)
90	ILLUMINA	ss3639336945	Oct 12, 2018 (152)
91	ILLUMINA	ss3639695848	Oct 12, 2018 (152)
92	ILLUMINA	ss3640807025	Oct 12, 2018 (152)
93	ILLUMINA	ss3643608755	Oct 12, 2018 (152)
94	URBANLAB	ss3648518563	Oct 12, 2018 (152)
95	ILLUMINA	ss3654154703	Oct 12, 2018 (152)
96	EGCUT_WGS	ss3668261188	Jul 13, 2019 (153)
97	EVA_DECODE	ss3718735906	Jul 13, 2019 (153)
98	ACPOP	ss3734188426	Jul 13, 2019 (153)
99	ILLUMINA	ss3745399632	Jul 13, 2019 (153)
100	EVA	ss3765957173	Jul 13, 2019 (153)
101	ILLUMINA	ss3772892933	Jul 13, 2019 (153)
102	PACBIO	ss3785682610	Jul 13, 2019 (153)
103	PACBIO	ss3791000214	Jul 13, 2019 (153)
104	PACBIO	ss3795879680	Jul 13, 2019 (153)
105	KHV_HUMAN_GENOMES	ss3809121164	Jul 13, 2019 (153)
106	EVA	ss3830312638	Apr 26, 2020 (154)
107	EVA	ss3838640682	Apr 26, 2020 (154)
108	EVA	ss3844090925	Apr 26, 2020 (154)
109	HGDP	ss3847859597	Apr 26, 2020 (154)
110	SGDP_PRJ	ss3866202837	Apr 26, 2020 (154)
111	KRGDB	ss3913194926	Apr 26, 2020 (154)
112	EVA	ss3985267270	Apr 26, 2021 (155)
113	EVA	ss4017311935	Apr 26, 2021 (155)
114	TOPMED	ss4729736387	Apr 26, 2021 (155)
115	TOMMO_GENOMICS	ss5180969946	Apr 26, 2021 (155)
116	1000G_HIGH_COVERAGE	ss5271167654	Oct 14, 2022 (156)
117	EVA	ss5315208539	Oct 14, 2022 (156)
118	EVA	ss5370497497	Oct 14, 2022 (156)
119	HUGCELL_USP	ss5468537699	Oct 14, 2022 (156)
120	1000G_HIGH_COVERAGE	ss5558512474	Oct 14, 2022 (156)
121	SANFORD_IMAGENETICS	ss5641961292	Oct 14, 2022 (156)
122	TOMMO_GENOMICS	ss5720153550	Oct 14, 2022 (156)
123	EVA	ss5799709802	Oct 14, 2022 (156)
124	YY_MCH	ss5808160086	Oct 14, 2022 (156)
125	EVA	ss5843310314	Oct 14, 2022 (156)
126	EVA	ss5855680430	Oct 14, 2022 (156)
127	EVA	ss5886896911	Oct 14, 2022 (156)
128	EVA	ss5971044891	Oct 14, 2022 (156)
129	EVA	ss5971044892	Oct 14, 2022 (156)
130	1000Genomes	NC_000006.11 - 162565718	Oct 12, 2018 (152)
131	1000Genomes_30x	NC_000006.12 - 162144686	Oct 14, 2022 (156)
132	The Avon Longitudinal Study of Parents and Children	NC_000006.11 - 162565718	Oct 12, 2018 (152)
133	Genome-wide autozygosity in Daghestan	NC_000006.10 - 162485708	Apr 26, 2020 (154)
134	Genetic variation in the Estonian population	NC_000006.11 - 162565718	Oct 12, 2018 (152)
135	The Danish reference pan genome	NC_000006.11 - 162565718	Apr 26, 2020 (154)
136	gnomAD - Genomes	NC_000006.12 - 162144686	Apr 26, 2021 (155)
137	Genome of the Netherlands Release 5	NC_000006.11 - 162565718	Apr 26, 2020 (154)
138	HGDP-CEPH-db Supplement 1	NC_000006.10 - 162485708	Apr 26, 2020 (154)
139	KOREAN population from KRGDB	NC_000006.11 - 162565718	Apr 26, 2020 (154)
140	Northern Sweden	NC_000006.11 - 162565718	Jul 13, 2019 (153)
141	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000006.11 - 162565718	Apr 26, 2021 (155)
142	Qatari	NC_000006.11 - 162565718	Apr 26, 2020 (154)
143	SGDP_PRJ	NC_000006.11 - 162565718	Apr 26, 2020 (154)
144	Siberian	NC_000006.11 - 162565718	Apr 26, 2020 (154)
145	8.3KJPN	NC_000006.11 - 162565718	Apr 26, 2021 (155)
146	14KJPN	NC_000006.12 - 162144686	Oct 14, 2022 (156)
147	TopMed	NC_000006.12 - 162144686	Apr 26, 2021 (155)
148	UK 10K study - Twins	NC_000006.11 - 162565718	Oct 12, 2018 (152)
149	A Vietnamese Genetic Variation Database	NC_000006.11 - 162565718	Jul 13, 2019 (153)
150	ALFA	NC_000006.12 - 162144686	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs17262640	Oct 08, 2004 (123)
rs58208103	May 24, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss82527233, ss3639336945, ss3639695848	NC_000006.9:162536128:T:C	NC_000006.12:162144685:T:C	(self)
453164, 537489, ss93596572, ss111245127, ss115423743, ss116803756, ss160690712, ss162967060, ss165133167, ss167458677, ss202704050, ss207389659, ss254791372, ss279110760, ss293778470, ss480979083, ss825517183, ss1397478825, ss1593321346, ss1712918176, ss3643608755, ss3847859597	NC_000006.10:162485707:T:C	NC_000006.12:162144685:T:C	(self)
35107098, 19580614, 13999436, 8155445, 8713912, 20372320, 7473291, 493197, 9028832, 18219817, 4870466, 38939253, 19580614, 4356987, ss222803867, ss233774166, ss240769999, ss480999551, ss481976932, ss485284450, ss537249218, ss559679047, ss654021679, ss778911888, ss783088138, ss784045610, ss832346579, ss832990529, ss833581358, ss834373241, ss983745066, ss1074219380, ss1323202793, ss1430964376, ss1581990506, ss1617199456, ss1660193489, ss1752613948, ss1804778802, ss1926986902, ss1970579207, ss2024160209, ss2152354112, ss2626570179, ss2634541838, ss2707993654, ss2847740064, ss2985394691, ss2986024003, ss3000322213, ss3347336308, ss3629709913, ss3632453329, ss3633446114, ss3634170094, ss3635099724, ss3635850337, ss3636828814, ss3637603245, ss3638670632, ss3640807025, ss3654154703, ss3668261188, ss3734188426, ss3745399632, ss3765957173, ss3772892933, ss3785682610, ss3791000214, ss3795879680, ss3830312638, ss3838640682, ss3866202837, ss3913194926, ss3985267270, ss4017311935, ss5180969946, ss5315208539, ss5370497497, ss5641961292, ss5799709802, ss5843310314, ss5971044891, ss5971044892	NC_000006.11:162565717:T:C	NC_000006.12:162144685:T:C	(self)
46038409, 247793808, 53990654, 567113945, 2286451135, ss2290312646, ss3025871644, ss3648518563, ss3718735906, ss3809121164, ss3844090925, ss4729736387, ss5271167654, ss5468537699, ss5558512474, ss5720153550, ss5808160086, ss5855680430, ss5886896911	NC_000006.12:162144685:T:C	NC_000006.12:162144685:T:C	(self)
ss6242731, ss24716566, ss44691747, ss66618912, ss67349605, ss67741422, ss68396807, ss70811322, ss71391587, ss75446598, ss79186665, ss84297741, ss98558711, ss104381412, ss122337232, ss142480729, ss142882687, ss154302242, ss157844007, ss159479085, ss171834841, ss173760208	NT_025741.15:66735174:T:C	NC_000006.12:162144685:T:C	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

No publications for rs4605857

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs4605857