Name: rs6496932
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs6496932

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr15:85282336 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>A / C>G
Variation Type: SNV Single Nucleotide Variation
Frequency: A=0.211735 (74773/353144, ALFA)
A=0.285798 (75648/264690, TOPMED)
A=0.285452 (39909/139810, GnomAD) (+ 21 more)
A=0.34651 (27270/78700, PAGE_STUDY)
A=0.30636 (8657/28258, 14KJPN)
A=0.30280 (5075/16760, 8.3KJPN)
A=0.3463 (2218/6404, 1000G_30x)
A=0.3435 (1720/5008, 1000G)
A=0.1767 (681/3854, ALSPAC)
A=0.1756 (651/3708, TWINSUK)
A=0.3498 (1025/2930, KOREAN)
A=0.3124 (651/2084, HGDP_Stanford)
A=0.3440 (646/1878, HapMap)
A=0.3395 (622/1832, Korea1K)
A=0.2264 (254/1122, Daghestan)
A=0.168 (168/998, GoNL)
A=0.192 (120/626, Chileans)
A=0.165 (99/600, NorthernSweden)
C=0.367 (102/278, SGDP_PRJ)
A=0.245 (53/216, Qatari)
A=0.318 (68/214, Vietnamese)
A=0.21 (18/84, Ancient Sardinia)
A=0.23 (9/40, GENOME_DK)
C=0.46 (13/28, Siberian)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: None
Publications: 6 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	358392	C=0.787481	A=0.212519, G=0.000000
European	Sub	305364	C=0.804397	A=0.195603, G=0.000000
African	Sub	12552	C=0.56047	A=0.43953, G=0.00000
African Others	Sub	448	C=0.498	A=0.502, G=0.000
African American	Sub	12104	C=0.56279	A=0.43721, G=0.00000
Asian	Sub	6960	C=0.6704	A=0.3296, G=0.0000
East Asian	Sub	4992	C=0.6661	A=0.3339, G=0.0000
Other Asian	Sub	1968	C=0.6814	A=0.3186, G=0.0000
Latin American 1	Sub	1280	C=0.6859	A=0.3141, G=0.0000
Latin American 2	Sub	9370	C=0.7819	A=0.2181, G=0.0000
South Asian	Sub	5216	C=0.6472	A=0.3528, G=0.0000
Other	Sub	17650	C=0.75422	A=0.24578, G=0.00000

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	353144	C=0.788265	A=0.211735, G=0.000000
Allele Frequency Aggregator	European	Sub	302090	C=0.804393	A=0.195607, G=0.000000
Allele Frequency Aggregator	Other	Sub	16828	C=0.75582	A=0.24418, G=0.00000
Allele Frequency Aggregator	African	Sub	11400	C=0.56202	A=0.43798, G=0.00000
Allele Frequency Aggregator	Latin American 2	Sub	9370	C=0.7819	A=0.2181, G=0.0000
Allele Frequency Aggregator	Asian	Sub	6960	C=0.6704	A=0.3296, G=0.0000
Allele Frequency Aggregator	South Asian	Sub	5216	C=0.6472	A=0.3528, G=0.0000
Allele Frequency Aggregator	Latin American 1	Sub	1280	C=0.6859	A=0.3141, G=0.0000
TopMed	Global	Study-wide	264690	C=0.714202	A=0.285798
gnomAD - Genomes	Global	Study-wide	139810	C=0.714548	A=0.285452
gnomAD - Genomes	European	Sub	75804	C=0.79692	A=0.20308
gnomAD - Genomes	African	Sub	41816	C=0.55950	A=0.44050
gnomAD - Genomes	American	Sub	13612	C=0.74809	A=0.25191
gnomAD - Genomes	Ashkenazi Jewish	Sub	3322	C=0.6963	A=0.3037
gnomAD - Genomes	East Asian	Sub	3114	C=0.6612	A=0.3388
gnomAD - Genomes	Other	Sub	2142	C=0.7190	A=0.2810
The PAGE Study	Global	Study-wide	78700	C=0.65349	A=0.34651
The PAGE Study	AfricanAmerican	Sub	32516	C=0.56381	A=0.43619
The PAGE Study	Mexican	Sub	10810	C=0.78538	A=0.21462
The PAGE Study	Asian	Sub	8318	C=0.6838	A=0.3162
The PAGE Study	PuertoRican	Sub	7918	C=0.7059	A=0.2941
The PAGE Study	NativeHawaiian	Sub	4534	C=0.6509	A=0.3491
The PAGE Study	Cuban	Sub	4230	C=0.7173	A=0.2827
The PAGE Study	Dominican	Sub	3826	C=0.6647	A=0.3353
The PAGE Study	CentralAmerican	Sub	2450	C=0.7294	A=0.2706
The PAGE Study	SouthAmerican	Sub	1982	C=0.7644	A=0.2356
The PAGE Study	NativeAmerican	Sub	1260	C=0.7627	A=0.2373
The PAGE Study	SouthAsian	Sub	856	C=0.630	A=0.370
14KJPN	JAPANESE	Study-wide	28258	C=0.69364	A=0.30636
8.3KJPN	JAPANESE	Study-wide	16760	C=0.69720	A=0.30280
1000Genomes_30x	Global	Study-wide	6404	C=0.6537	A=0.3463
1000Genomes_30x	African	Sub	1786	C=0.5106	A=0.4894
1000Genomes_30x	Europe	Sub	1266	C=0.7717	A=0.2283
1000Genomes_30x	South Asian	Sub	1202	C=0.6215	A=0.3785
1000Genomes_30x	East Asian	Sub	1170	C=0.6726	A=0.3274
1000Genomes_30x	American	Sub	980	C=0.779	A=0.221
1000Genomes	Global	Study-wide	5008	C=0.6565	A=0.3435
1000Genomes	African	Sub	1322	C=0.5136	A=0.4864
1000Genomes	East Asian	Sub	1008	C=0.6786	A=0.3214
1000Genomes	Europe	Sub	1006	C=0.7644	A=0.2356
1000Genomes	South Asian	Sub	978	C=0.630	A=0.370
1000Genomes	American	Sub	694	C=0.778	A=0.222
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.8233	A=0.1767
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.8244	A=0.1756
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.6502	A=0.3498, G=0.0000
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	C=0.6876	A=0.3124
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	C=0.694	A=0.306
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	C=0.681	A=0.319
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	C=0.717	A=0.283
HGDP-CEPH-db Supplement 1	Europe	Sub	320	C=0.781	A=0.219
HGDP-CEPH-db Supplement 1	Africa	Sub	242	C=0.483	A=0.517
HGDP-CEPH-db Supplement 1	America	Sub	216	C=0.824	A=0.176
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	C=0.40	A=0.60
HapMap	Global	Study-wide	1878	C=0.6560	A=0.3440
HapMap	American	Sub	766	C=0.687	A=0.313
HapMap	African	Sub	682	C=0.588	A=0.412
HapMap	Asian	Sub	254	C=0.657	A=0.343
HapMap	Europe	Sub	176	C=0.784	A=0.216
Korean Genome Project	KOREAN	Study-wide	1832	C=0.6605	A=0.3395
Genome-wide autozygosity in Daghestan	Global	Study-wide	1122	C=0.7736	A=0.2264
Genome-wide autozygosity in Daghestan	Daghestan	Sub	618	C=0.812	A=0.188
Genome-wide autozygosity in Daghestan	Near_East	Sub	144	C=0.715	A=0.285
Genome-wide autozygosity in Daghestan	Central Asia	Sub	120	C=0.758	A=0.242
Genome-wide autozygosity in Daghestan	Europe	Sub	106	C=0.840	A=0.160
Genome-wide autozygosity in Daghestan	South Asian	Sub	98	C=0.55	A=0.45
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	C=0.81	A=0.19
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.832	A=0.168
Chileans	Chilean	Study-wide	626	C=0.808	A=0.192
Northern Sweden	ACPOP	Study-wide	600	C=0.835	A=0.165
SGDP_PRJ	Global	Study-wide	278	C=0.367	A=0.633
Qatari	Global	Study-wide	216	C=0.755	A=0.245
A Vietnamese Genetic Variation Database	Global	Study-wide	214	C=0.682	A=0.318
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	84	C=0.79	A=0.21
The Danish reference pan genome	Danish	Study-wide	40	C=0.78	A=0.23
Siberian	Global	Study-wide	28	C=0.46	A=0.54

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 15	NC_000015.10:g.85282336C>A
GRCh38.p14 chr 15	NC_000015.10:g.85282336C>G
GRCh37.p13 chr 15	NC_000015.9:g.85825567C>A
GRCh37.p13 chr 15	NC_000015.9:g.85825567C>G

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	A	G
GRCh38.p14 chr 15	NC_000015.10:g.85282336=	NC_000015.10:g.85282336C>A	NC_000015.10:g.85282336C>G
GRCh37.p13 chr 15	NC_000015.9:g.85825567=	NC_000015.9:g.85825567C>A	NC_000015.9:g.85825567C>G

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

158 SubSNP, 26 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	BCM_SSAHASNP	ss10789795	Jul 11, 2003 (116)
2	WI_SSAHASNP	ss12332837	Jul 11, 2003 (116)
3	AFFY	ss66291318	Nov 29, 2006 (127)
4	ILLUMINA	ss66784111	Nov 29, 2006 (127)
5	ILLUMINA	ss67463261	Nov 29, 2006 (127)
6	ILLUMINA	ss67817035	Nov 29, 2006 (127)
7	PERLEGEN	ss69183258	May 16, 2007 (127)
8	ILLUMINA	ss70868761	May 23, 2008 (130)
9	ILLUMINA	ss71457269	May 16, 2007 (127)
10	ILLUMINA	ss75751046	Dec 06, 2007 (129)
11	AFFY	ss75956270	Dec 06, 2007 (129)
12	ILLUMINA	ss79223081	Dec 14, 2007 (130)
13	KRIBB_YJKIM	ss84490647	Dec 14, 2007 (130)
14	HGSV	ss84706911	Dec 14, 2007 (130)
15	HUMANGENOME_JCVI	ss96829561	Feb 04, 2009 (130)
16	BGI	ss103257452	Dec 01, 2009 (131)
17	1000GENOMES	ss114480068	Jan 25, 2009 (130)
18	ILLUMINA-UK	ss118308729	Feb 14, 2009 (130)
19	ILLUMINA	ss122553928	Dec 01, 2009 (131)
20	ENSEMBL	ss144094010	Dec 01, 2009 (131)
21	ILLUMINA	ss154363976	Dec 01, 2009 (131)
22	GMI	ss156809845	Dec 01, 2009 (131)
23	ILLUMINA	ss159540144	Dec 01, 2009 (131)
24	ILLUMINA	ss160780420	Dec 01, 2009 (131)
25	COMPLETE_GENOMICS	ss168417934	Jul 04, 2010 (132)
26	AFFY	ss169648249	Jul 04, 2010 (132)
27	COMPLETE_GENOMICS	ss170079451	Jul 04, 2010 (132)
28	ILLUMINA	ss172135901	Jul 04, 2010 (132)
29	ILLUMINA	ss174018305	Jul 04, 2010 (132)
30	BUSHMAN	ss201114995	Jul 04, 2010 (132)
31	1000GENOMES	ss227008603	Jul 14, 2010 (132)
32	1000GENOMES	ss236861067	Jul 15, 2010 (132)
33	1000GENOMES	ss243232825	Jul 15, 2010 (132)
34	GMI	ss282344319	May 04, 2012 (137)
35	PJP	ss291765338	May 09, 2011 (134)
36	ILLUMINA	ss481262588	May 04, 2012 (137)
37	ILLUMINA	ss481286836	May 04, 2012 (137)
38	ILLUMINA	ss482271111	Sep 08, 2015 (146)
39	ILLUMINA	ss485426568	May 04, 2012 (137)
40	EXOME_CHIP	ss491498776	May 04, 2012 (137)
41	ILLUMINA	ss537356831	Sep 08, 2015 (146)
42	TISHKOFF	ss564618386	Apr 25, 2013 (138)
43	SSMP	ss660359942	Apr 25, 2013 (138)
44	ILLUMINA	ss778570405	Sep 08, 2015 (146)
45	ILLUMINA	ss780685864	Sep 08, 2015 (146)
46	ILLUMINA	ss783158729	Sep 08, 2015 (146)
47	ILLUMINA	ss783359368	Sep 08, 2015 (146)
48	ILLUMINA	ss784114559	Sep 08, 2015 (146)
49	ILLUMINA	ss825553599	Jul 19, 2016 (147)
50	ILLUMINA	ss832418064	Sep 08, 2015 (146)
51	ILLUMINA	ss833051351	Jul 13, 2019 (153)
52	ILLUMINA	ss834027418	Sep 08, 2015 (146)
53	EVA-GONL	ss992028382	Aug 21, 2014 (142)
54	JMKIDD_LAB	ss1080298059	Aug 21, 2014 (142)
55	1000GENOMES	ss1354405517	Aug 21, 2014 (142)
56	HAMMER_LAB	ss1397703149	Sep 08, 2015 (146)
57	DDI	ss1427699038	Apr 01, 2015 (144)
58	EVA_GENOME_DK	ss1577730781	Apr 01, 2015 (144)
59	EVA_UK10K_ALSPAC	ss1633501025	Apr 01, 2015 (144)
60	EVA_UK10K_TWINSUK	ss1676495058	Apr 01, 2015 (144)
61	EVA_DECODE	ss1696054876	Apr 01, 2015 (144)
62	EVA_SVP	ss1713507504	Apr 01, 2015 (144)
63	ILLUMINA	ss1752174714	Sep 08, 2015 (146)
64	ILLUMINA	ss1752174715	Sep 08, 2015 (146)
65	HAMMER_LAB	ss1808305290	Sep 08, 2015 (146)
66	ILLUMINA	ss1917900070	Feb 12, 2016 (147)
67	WEILL_CORNELL_DGM	ss1935429671	Feb 12, 2016 (147)
68	ILLUMINA	ss1946400803	Feb 12, 2016 (147)
69	ILLUMINA	ss1946400804	Feb 12, 2016 (147)
70	ILLUMINA	ss1959632834	Feb 12, 2016 (147)
71	ILLUMINA	ss1959632835	Feb 12, 2016 (147)
72	GENOMED	ss1968162458	Jul 19, 2016 (147)
73	JJLAB	ss2028497976	Sep 14, 2016 (149)
74	USC_VALOUEV	ss2156906751	Dec 20, 2016 (150)
75	SYSTEMSBIOZJU	ss2628744333	Nov 08, 2017 (151)
76	ILLUMINA	ss2633259717	Nov 08, 2017 (151)
77	ILLUMINA	ss2633259718	Nov 08, 2017 (151)
78	ILLUMINA	ss2633259719	Nov 08, 2017 (151)
79	GRF	ss2701390735	Nov 08, 2017 (151)
80	ILLUMINA	ss2710822304	Nov 08, 2017 (151)
81	GNOMAD	ss2937630508	Nov 08, 2017 (151)
82	AFFY	ss2985049262	Nov 08, 2017 (151)
83	AFFY	ss2985690888	Nov 08, 2017 (151)
84	SWEGEN	ss3013671383	Nov 08, 2017 (151)
85	ILLUMINA	ss3021656201	Nov 08, 2017 (151)
86	ILLUMINA	ss3021656202	Nov 08, 2017 (151)
87	BIOINF_KMB_FNS_UNIBA	ss3028072918	Nov 08, 2017 (151)
88	CSHL	ss3351219603	Nov 08, 2017 (151)
89	ILLUMINA	ss3625679867	Oct 12, 2018 (152)
90	ILLUMINA	ss3627417366	Oct 12, 2018 (152)
91	ILLUMINA	ss3627417367	Oct 12, 2018 (152)
92	ILLUMINA	ss3631250375	Oct 12, 2018 (152)
93	ILLUMINA	ss3633105201	Oct 12, 2018 (152)
94	ILLUMINA	ss3633810209	Oct 12, 2018 (152)
95	ILLUMINA	ss3634618363	Oct 12, 2018 (152)
96	ILLUMINA	ss3634618364	Oct 12, 2018 (152)
97	ILLUMINA	ss3635498938	Oct 12, 2018 (152)
98	ILLUMINA	ss3636309210	Oct 12, 2018 (152)
99	ILLUMINA	ss3637250253	Oct 12, 2018 (152)
100	ILLUMINA	ss3638099679	Oct 12, 2018 (152)
101	ILLUMINA	ss3639062255	Oct 12, 2018 (152)
102	ILLUMINA	ss3639536730	Oct 12, 2018 (152)
103	ILLUMINA	ss3640325683	Oct 12, 2018 (152)
104	ILLUMINA	ss3640325684	Oct 12, 2018 (152)
105	ILLUMINA	ss3641064185	Oct 12, 2018 (152)
106	ILLUMINA	ss3641359610	Oct 12, 2018 (152)
107	ILLUMINA	ss3643082941	Oct 12, 2018 (152)
108	ILLUMINA	ss3644653909	Oct 12, 2018 (152)
109	ILLUMINA	ss3644653910	Oct 12, 2018 (152)
110	URBANLAB	ss3650407780	Oct 12, 2018 (152)
111	ILLUMINA	ss3652058675	Oct 12, 2018 (152)
112	ILLUMINA	ss3652058676	Oct 12, 2018 (152)
113	ILLUMINA	ss3653821654	Oct 12, 2018 (152)
114	EVA_DECODE	ss3698357812	Jul 13, 2019 (153)
115	ILLUMINA	ss3725520299	Jul 13, 2019 (153)
116	ACPOP	ss3741126129	Jul 13, 2019 (153)
117	ILLUMINA	ss3744134519	Jul 13, 2019 (153)
118	ILLUMINA	ss3744424128	Jul 13, 2019 (153)
119	ILLUMINA	ss3744918896	Jul 13, 2019 (153)
120	ILLUMINA	ss3744918897	Jul 13, 2019 (153)
121	EVA	ss3753379614	Jul 13, 2019 (153)
122	PAGE_CC	ss3771846591	Jul 13, 2019 (153)
123	ILLUMINA	ss3772417408	Jul 13, 2019 (153)
124	ILLUMINA	ss3772417409	Jul 13, 2019 (153)
125	PACBIO	ss3787914220	Jul 13, 2019 (153)
126	PACBIO	ss3792915253	Jul 13, 2019 (153)
127	PACBIO	ss3797799833	Jul 13, 2019 (153)
128	KHV_HUMAN_GENOMES	ss3818681812	Jul 13, 2019 (153)
129	EVA	ss3834350295	Apr 27, 2020 (154)
130	HGDP	ss3847531203	Apr 27, 2020 (154)
131	SGDP_PRJ	ss3883415189	Apr 27, 2020 (154)
132	KRGDB	ss3932657066	Apr 27, 2020 (154)
133	KOGIC	ss3976634727	Apr 27, 2020 (154)
134	EVA	ss3984705217	Apr 26, 2021 (155)
135	EVA	ss3984705218	Apr 26, 2021 (155)
136	EVA	ss3985730934	Apr 26, 2021 (155)
137	EVA	ss4017714240	Apr 26, 2021 (155)
138	TOPMED	ss4999707388	Apr 26, 2021 (155)
139	TOMMO_GENOMICS	ss5217313875	Apr 26, 2021 (155)
140	EVA	ss5237555080	Apr 26, 2021 (155)
141	1000G_HIGH_COVERAGE	ss5299275850	Oct 16, 2022 (156)
142	EVA	ss5315802180	Oct 16, 2022 (156)
143	EVA	ss5420756166	Oct 16, 2022 (156)
144	HUGCELL_USP	ss5492907240	Oct 16, 2022 (156)
145	EVA	ss5511505654	Oct 16, 2022 (156)
146	1000G_HIGH_COVERAGE	ss5601094672	Oct 16, 2022 (156)
147	SANFORD_IMAGENETICS	ss5624367179	Oct 16, 2022 (156)
148	SANFORD_IMAGENETICS	ss5657976014	Oct 16, 2022 (156)
149	TOMMO_GENOMICS	ss5771460465	Oct 16, 2022 (156)
150	EVA	ss5799944497	Oct 16, 2022 (156)
151	YY_MCH	ss5815543564	Oct 16, 2022 (156)
152	EVA	ss5828523223	Oct 16, 2022 (156)
153	EVA	ss5847453208	Oct 16, 2022 (156)
154	EVA	ss5847752493	Oct 16, 2022 (156)
155	EVA	ss5851388518	Oct 16, 2022 (156)
156	EVA	ss5876825204	Oct 16, 2022 (156)
157	EVA	ss5949395146	Oct 16, 2022 (156)
158	EVA	ss5979469214	Oct 16, 2022 (156)
159	1000Genomes	NC_000015.9 - 85825567	Oct 12, 2018 (152)
160	1000Genomes_30x	NC_000015.10 - 85282336	Oct 16, 2022 (156)
161	The Avon Longitudinal Study of Parents and Children	NC_000015.9 - 85825567	Oct 12, 2018 (152)
162	Chileans	NC_000015.9 - 85825567	Apr 27, 2020 (154)
163	Genome-wide autozygosity in Daghestan	NC_000015.8 - 83626571	Apr 27, 2020 (154)
164	The Danish reference pan genome	NC_000015.9 - 85825567	Apr 27, 2020 (154)
165	gnomAD - Genomes	NC_000015.10 - 85282336	Apr 26, 2021 (155)
166	Genome of the Netherlands Release 5	NC_000015.9 - 85825567	Apr 27, 2020 (154)
167	HGDP-CEPH-db Supplement 1	NC_000015.8 - 83626571	Apr 27, 2020 (154)
168	HapMap	NC_000015.10 - 85282336	Apr 27, 2020 (154)
169	KOREAN population from KRGDB	NC_000015.9 - 85825567	Apr 27, 2020 (154)
170	Korean Genome Project	NC_000015.10 - 85282336	Apr 27, 2020 (154)
171	Northern Sweden	NC_000015.9 - 85825567	Jul 13, 2019 (153)
172	The PAGE Study	NC_000015.10 - 85282336	Jul 13, 2019 (153)
173	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000015.9 - 85825567	Apr 26, 2021 (155)
174	CNV burdens in cranial meningiomas Submission ignored due to conflicting rows: Row 254745 (NC_000015.9:85825566:C:A 278/790) Row 254746 (NC_000015.9:85825566:C:A 278/788)	-	Apr 26, 2021 (155)
175	CNV burdens in cranial meningiomas Submission ignored due to conflicting rows: Row 254745 (NC_000015.9:85825566:C:A 278/790) Row 254746 (NC_000015.9:85825566:C:A 278/788)	-	Apr 26, 2021 (155)
176	Qatari	NC_000015.9 - 85825567	Apr 27, 2020 (154)
177	SGDP_PRJ	NC_000015.9 - 85825567	Apr 27, 2020 (154)
178	Siberian	NC_000015.9 - 85825567	Apr 27, 2020 (154)
179	8.3KJPN	NC_000015.9 - 85825567	Apr 26, 2021 (155)
180	14KJPN	NC_000015.10 - 85282336	Oct 16, 2022 (156)
181	TopMed	NC_000015.10 - 85282336	Apr 26, 2021 (155)
182	UK 10K study - Twins	NC_000015.9 - 85825567	Oct 12, 2018 (152)
183	A Vietnamese Genetic Variation Database	NC_000015.9 - 85825567	Jul 13, 2019 (153)
184	ALFA	NC_000015.10 - 85282336	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs57625245	May 23, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
173263, 209095, ss84706911, ss114480068, ss118308729, ss168417934, ss170079451, ss201114995, ss282344319, ss291765338, ss481262588, ss825553599, ss1397703149, ss1696054876, ss1713507504, ss3639062255, ss3639536730, ss3643082941, ss3847531203	NC_000015.8:83626570:C:A	NC_000015.10:85282335:C:A	(self)
67511218, 37490879, 157993, 3950696, 16729104, 39834460, 14410994, 956861, 17471601, 35432169, 9423105, 75283182, 37490879, 8333386, ss227008603, ss236861067, ss243232825, ss481286836, ss482271111, ss485426568, ss491498776, ss537356831, ss564618386, ss660359942, ss778570405, ss780685864, ss783158729, ss783359368, ss784114559, ss832418064, ss833051351, ss834027418, ss992028382, ss1080298059, ss1354405517, ss1427699038, ss1577730781, ss1633501025, ss1676495058, ss1752174714, ss1752174715, ss1808305290, ss1917900070, ss1935429671, ss1946400803, ss1946400804, ss1959632834, ss1959632835, ss1968162458, ss2028497976, ss2156906751, ss2628744333, ss2633259717, ss2633259718, ss2633259719, ss2701390735, ss2710822304, ss2937630508, ss2985049262, ss2985690888, ss3013671383, ss3021656201, ss3021656202, ss3351219603, ss3625679867, ss3627417366, ss3627417367, ss3631250375, ss3633105201, ss3633810209, ss3634618363, ss3634618364, ss3635498938, ss3636309210, ss3637250253, ss3638099679, ss3640325683, ss3640325684, ss3641064185, ss3641359610, ss3644653909, ss3644653910, ss3652058675, ss3652058676, ss3653821654, ss3741126129, ss3744134519, ss3744424128, ss3744918896, ss3744918897, ss3753379614, ss3772417408, ss3772417409, ss3787914220, ss3792915253, ss3797799833, ss3834350295, ss3883415189, ss3932657066, ss3984705217, ss3984705218, ss3985730934, ss4017714240, ss5217313875, ss5237555080, ss5315802180, ss5420756166, ss5511505654, ss5624367179, ss5657976014, ss5799944497, ss5828523223, ss5847453208, ss5847752493, ss5949395146, ss5979469214	NC_000015.9:85825566:C:A	NC_000015.10:85282335:C:A	(self)
88620607, 476021159, 1306732, 33012728, 1068060, 105297569, 215253048, 2757388407, ss3028072918, ss3650407780, ss3698357812, ss3725520299, ss3771846591, ss3818681812, ss3976634727, ss4999707388, ss5299275850, ss5492907240, ss5601094672, ss5771460465, ss5815543564, ss5851388518, ss5876825204	NC_000015.10:85282335:C:A	NC_000015.10:85282335:C:A	(self)
ss10789795, ss12332837	NT_010274.15:791093:C:A	NC_000015.10:85282335:C:A	(self)
ss66291318, ss66784111, ss67463261, ss67817035, ss69183258, ss70868761, ss71457269, ss75751046, ss75956270, ss79223081, ss84490647, ss96829561, ss103257452, ss122553928, ss144094010, ss154363976, ss156809845, ss159540144, ss160780420, ss169648249, ss172135901, ss174018305	NT_010274.17:791093:C:A	NC_000015.10:85282335:C:A	(self)
39834460, ss3932657066	NC_000015.9:85825566:C:G	NC_000015.10:85282335:C:G	(self)
2757388407	NC_000015.10:85282335:C:G	NC_000015.10:85282335:C:G	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

6 citations for rs6496932

PMID	Title	Author	Year	Journal
20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Vitart V et al.	2010	Human molecular genetics
21984434	Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations.	Cornes BK et al.	2012	Human molecular genetics
22605921	Genome-wide association study of primary open angle glaucoma risk and quantitative traits.	Gibson J et al.	2012	Molecular vision
23110055	Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy.	Igo RP Jr et al.	2012	PloS one
23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Lu Y et al.	2013	Nature genetics
26690118	An Updated Review on the Genetics of Primary Open Angle Glaucoma.	Abu-Amero K et al.	2015	International journal of molecular sciences

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs6496932