Name: rs12446219
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs12446219

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr16:84415015 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: T>A / T>C
Variation Type: SNV Single Nucleotide Variation
Frequency: T=0.470059 (124420/264690, TOPMED)
T=0.410358 (47975/116910, ALFA)
C=0.42926 (12130/28258, 14KJPN) (+ 20 more)
C=0.42691 (7155/16760, 8.3KJPN)
C=0.4166 (2668/6404, 1000G_30x)
C=0.4193 (2100/5008, 1000G)
T=0.3913 (1753/4480, Estonian)
T=0.3503 (1350/3854, ALSPAC)
T=0.3544 (1314/3708, TWINSUK)
C=0.4023 (1177/2926, KOREAN)
C=0.4789 (997/2082, HGDP_Stanford)
C=0.4456 (843/1892, HapMap)
C=0.4192 (768/1832, Korea1K)
T=0.3836 (435/1134, Daghestan)
T=0.368 (367/998, GoNL)
C=0.497 (311/626, Chileans)
T=0.382 (229/600, NorthernSweden)
T=0.318 (122/384, SGDP_PRJ)
T=0.435 (94/216, Qatari)
C=0.346 (74/214, Vietnamese)
T=0.31 (22/72, Ancient Sardinia)
T=0.33 (13/40, GENOME_DK)
T=0.28 (11/40, Siberian)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: ATP2C2 : Intron Variant
Publications: 1 citation
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	117004	T=0.410294	A=0.000000, C=0.589706
European	Sub	89826	T=0.36931	A=0.00000, C=0.63069
African	Sub	8216	T=0.6358	A=0.0000, C=0.3642
African Others	Sub	284	T=0.669	A=0.000, C=0.331
African American	Sub	7932	T=0.6346	A=0.0000, C=0.3654
Asian	Sub	524	T=0.689	A=0.000, C=0.311
East Asian	Sub	422	T=0.666	A=0.000, C=0.334
Other Asian	Sub	102	T=0.784	A=0.000, C=0.216
Latin American 1	Sub	728	T=0.496	A=0.000, C=0.504
Latin American 2	Sub	7224	T=0.5372	A=0.0000, C=0.4628
South Asian	Sub	4960	T=0.5425	A=0.0000, C=0.4575
Other	Sub	5526	T=0.4187	A=0.0000, C=0.5813

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	T=0.470059	C=0.529941
Allele Frequency Aggregator	Total	Global	116910	T=0.410358	A=0.000000, C=0.589642
Allele Frequency Aggregator	European	Sub	89750	T=0.36936	A=0.00000, C=0.63064
Allele Frequency Aggregator	African	Sub	8216	T=0.6358	A=0.0000, C=0.3642
Allele Frequency Aggregator	Latin American 2	Sub	7224	T=0.5372	A=0.0000, C=0.4628
Allele Frequency Aggregator	Other	Sub	5508	T=0.4188	A=0.0000, C=0.5812
Allele Frequency Aggregator	South Asian	Sub	4960	T=0.5425	A=0.0000, C=0.4575
Allele Frequency Aggregator	Latin American 1	Sub	728	T=0.496	A=0.000, C=0.504
Allele Frequency Aggregator	Asian	Sub	524	T=0.689	A=0.000, C=0.311
14KJPN	JAPANESE	Study-wide	28258	T=0.57074	C=0.42926
8.3KJPN	JAPANESE	Study-wide	16760	T=0.57309	C=0.42691
1000Genomes_30x	Global	Study-wide	6404	T=0.5834	C=0.4166
1000Genomes_30x	African	Sub	1786	T=0.6713	C=0.3287
1000Genomes_30x	Europe	Sub	1266	T=0.3689	C=0.6311
1000Genomes_30x	South Asian	Sub	1202	T=0.6423	C=0.3577
1000Genomes_30x	East Asian	Sub	1170	T=0.6667	C=0.3333
1000Genomes_30x	American	Sub	980	T=0.529	C=0.471
1000Genomes	Global	Study-wide	5008	T=0.5807	C=0.4193
1000Genomes	African	Sub	1322	T=0.6589	C=0.3411
1000Genomes	East Asian	Sub	1008	T=0.6647	C=0.3353
1000Genomes	Europe	Sub	1006	T=0.3648	C=0.6352
1000Genomes	South Asian	Sub	978	T=0.644	C=0.356
1000Genomes	American	Sub	694	T=0.533	C=0.467
Genetic variation in the Estonian population	Estonian	Study-wide	4480	T=0.3913	C=0.6087
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.3503	C=0.6497
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.3544	C=0.6456
KOREAN population from KRGDB	KOREAN	Study-wide	2926	T=0.5977	C=0.4023
HGDP-CEPH-db Supplement 1	Global	Study-wide	2082	T=0.5211	C=0.4789
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	T=0.630	C=0.370
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	412	T=0.473	C=0.527
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	T=0.377	C=0.623
HGDP-CEPH-db Supplement 1	Europe	Sub	320	T=0.303	C=0.697
HGDP-CEPH-db Supplement 1	Africa	Sub	242	T=0.632	C=0.368
HGDP-CEPH-db Supplement 1	America	Sub	216	T=0.657	C=0.343
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	T=0.97	C=0.03
HapMap	Global	Study-wide	1892	T=0.5544	C=0.4456
HapMap	American	Sub	770	T=0.565	C=0.435
HapMap	African	Sub	692	T=0.581	C=0.419
HapMap	Asian	Sub	254	T=0.594	C=0.406
HapMap	Europe	Sub	176	T=0.347	C=0.653
Korean Genome Project	KOREAN	Study-wide	1832	T=0.5808	C=0.4192
Genome-wide autozygosity in Daghestan	Global	Study-wide	1134	T=0.3836	C=0.6164
Genome-wide autozygosity in Daghestan	Daghestan	Sub	628	T=0.347	C=0.653
Genome-wide autozygosity in Daghestan	Near_East	Sub	144	T=0.368	C=0.632
Genome-wide autozygosity in Daghestan	Central Asia	Sub	120	T=0.483	C=0.517
Genome-wide autozygosity in Daghestan	Europe	Sub	108	T=0.343	C=0.657
Genome-wide autozygosity in Daghestan	South Asian	Sub	98	T=0.63	C=0.37
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	T=0.19	C=0.81
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	T=0.368	C=0.632
Chileans	Chilean	Study-wide	626	T=0.503	C=0.497
Northern Sweden	ACPOP	Study-wide	600	T=0.382	C=0.618
SGDP_PRJ	Global	Study-wide	384	T=0.318	C=0.682
Qatari	Global	Study-wide	216	T=0.435	C=0.565
A Vietnamese Genetic Variation Database	Global	Study-wide	214	T=0.654	C=0.346
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	72	T=0.31	C=0.69
The Danish reference pan genome	Danish	Study-wide	40	T=0.33	C=0.68
Siberian	Global	Study-wide	40	T=0.28	C=0.72

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 16	NC_000016.10:g.84415015T>A
GRCh38.p14 chr 16	NC_000016.10:g.84415015T>C
GRCh37.p13 chr 16	NC_000016.9:g.84448621T>A
GRCh37.p13 chr 16	NC_000016.9:g.84448621T>C

Gene: ATP2C2, ATPase secretory pathway Ca2+ transporting 2 (plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ATP2C2 transcript variant 1	NM_001286527.3:c.516-468T… NM_001286527.3:c.516-468T>A	N/A	Intron Variant
ATP2C2 transcript variant 3	NM_001291454.2:c.63-468T>A	N/A	Intron Variant
ATP2C2 transcript variant 2	NM_014861.4:c.516-468T>A	N/A	Intron Variant
ATP2C2 transcript variant X1	XM_011523486.3:c.447-468T… XM_011523486.3:c.447-468T>A	N/A	Intron Variant
ATP2C2 transcript variant X2	XM_047434994.1:c.447-468T… XM_047434994.1:c.447-468T>A	N/A	Intron Variant
ATP2C2 transcript variant X3	XM_011523487.3:c.	N/A	Genic Upstream Transcript Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	T=	A	C
GRCh38.p14 chr 16	NC_000016.10:g.84415015=	NC_000016.10:g.84415015T>A	NC_000016.10:g.84415015T>C
GRCh37.p13 chr 16	NC_000016.9:g.84448621=	NC_000016.9:g.84448621T>A	NC_000016.9:g.84448621T>C
ATP2C2 transcript variant 1	NM_001286527.3:c.516-468=	NM_001286527.3:c.516-468T>A	NM_001286527.3:c.516-468T>C
ATP2C2 transcript variant 3	NM_001291454.2:c.63-468=	NM_001291454.2:c.63-468T>A	NM_001291454.2:c.63-468T>C
ATP2C2 transcript variant 2	NM_014861.2:c.516-468=	NM_014861.2:c.516-468T>A	NM_014861.2:c.516-468T>C
ATP2C2 transcript variant 2	NM_014861.4:c.516-468=	NM_014861.4:c.516-468T>A	NM_014861.4:c.516-468T>C
ATP2C2 transcript variant X1	XM_005256270.1:c.516-468=	XM_005256270.1:c.516-468T>A	XM_005256270.1:c.516-468T>C
ATP2C2 transcript variant X2	XM_005256271.1:c.63-468=	XM_005256271.1:c.63-468T>A	XM_005256271.1:c.63-468T>C
ATP2C2 transcript variant X1	XM_011523486.3:c.447-468=	XM_011523486.3:c.447-468T>A	XM_011523486.3:c.447-468T>C
ATP2C2 transcript variant X2	XM_047434994.1:c.447-468=	XM_047434994.1:c.447-468T>A	XM_047434994.1:c.447-468T>C

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

110 SubSNP, 25 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	CSHL-HAPMAP	ss19343803	Feb 28, 2004 (120)
2	PERLEGEN	ss23510612	Sep 20, 2004 (123)
3	ABI	ss43818832	Mar 14, 2006 (126)
4	ILLUMINA	ss67007610	Dec 01, 2006 (127)
5	ILLUMINA	ss67326902	Dec 01, 2006 (127)
6	ILLUMINA	ss68129378	Dec 12, 2006 (127)
7	PERLEGEN	ss69353256	May 18, 2007 (127)
8	ILLUMINA	ss70568565	May 24, 2008 (130)
9	ILLUMINA	ss71108880	May 18, 2007 (127)
10	ILLUMINA	ss75579877	Dec 06, 2007 (129)
11	AFFY	ss76616225	Dec 08, 2007 (130)
12	KRIBB_YJKIM	ss85222028	Dec 15, 2007 (130)
13	BCMHGSC_JDW	ss90480824	Mar 24, 2008 (129)
14	HUMANGENOME_JCVI	ss96703929	Feb 04, 2009 (130)
15	1000GENOMES	ss109531233	Jan 24, 2009 (130)
16	ENSEMBL	ss136858914	Dec 01, 2009 (131)
17	ILLUMINA	ss153198906	Dec 01, 2009 (131)
18	GMI	ss157664075	Dec 01, 2009 (131)
19	ILLUMINA	ss159217487	Dec 01, 2009 (131)
20	ILLUMINA	ss160271529	Dec 01, 2009 (131)
21	ENSEMBL	ss161814109	Dec 01, 2009 (131)
22	COMPLETE_GENOMICS	ss168619126	Jul 04, 2010 (132)
23	COMPLETE_GENOMICS	ss171654447	Jul 04, 2010 (132)
24	ILLUMINA	ss172085753	Jul 04, 2010 (132)
25	BUSHMAN	ss202024484	Jul 04, 2010 (132)
26	BCM-HGSC-SUB	ss207589343	Jul 04, 2010 (132)
27	1000GENOMES	ss211752772	Jul 14, 2010 (132)
28	1000GENOMES	ss227385493	Jul 14, 2010 (132)
29	1000GENOMES	ss237127877	Jul 15, 2010 (132)
30	1000GENOMES	ss243448074	Jul 15, 2010 (132)
31	GMI	ss282634603	May 04, 2012 (137)
32	GMI	ss287121340	Apr 25, 2013 (138)
33	PJP	ss291894151	May 09, 2011 (134)
34	ILLUMINA	ss480302747	Sep 08, 2015 (146)
35	ILLUMINA	ss483573642	May 04, 2012 (137)
36	ILLUMINA	ss483878645	May 04, 2012 (137)
37	ILLUMINA	ss536073687	Sep 08, 2015 (146)
38	TISHKOFF	ss565072472	Apr 25, 2013 (138)
39	SSMP	ss660850348	Apr 25, 2013 (138)
40	ILLUMINA	ss780442533	Sep 08, 2015 (146)
41	ILLUMINA	ss782382931	Sep 08, 2015 (146)
42	ILLUMINA	ss832729882	Aug 21, 2014 (142)
43	ILLUMINA	ss833320712	Aug 21, 2014 (142)
44	ILLUMINA	ss835932254	Sep 08, 2015 (146)
45	EVA-GONL	ss992769303	Aug 21, 2014 (142)
46	JMKIDD_LAB	ss1080827630	Aug 21, 2014 (142)
47	1000GENOMES	ss1357318477	Aug 21, 2014 (142)
48	HAMMER_LAB	ss1397723616	Sep 08, 2015 (146)
49	DDI	ss1427929025	Apr 01, 2015 (144)
50	EVA_GENOME_DK	ss1578027664	Apr 01, 2015 (144)
51	EVA_UK10K_ALSPAC	ss1635000839	Apr 01, 2015 (144)
52	EVA_UK10K_TWINSUK	ss1677994872	Apr 01, 2015 (144)
53	EVA_DECODE	ss1696810940	Apr 01, 2015 (144)
54	EVA_SVP	ss1713559670	Apr 01, 2015 (144)
55	HAMMER_LAB	ss1808634360	Sep 08, 2015 (146)
56	WEILL_CORNELL_DGM	ss1936203048	Feb 12, 2016 (147)
57	GENOMED	ss1968321485	Jul 19, 2016 (147)
58	JJLAB	ss2028892789	Sep 14, 2016 (149)
59	ILLUMINA	ss2095070186	Dec 20, 2016 (150)
60	USC_VALOUEV	ss2157331228	Dec 20, 2016 (150)
61	HUMAN_LONGEVITY	ss2214362843	Dec 20, 2016 (150)
62	SYSTEMSBIOZJU	ss2628936817	Nov 08, 2017 (151)
63	ILLUMINA	ss2633353909	Nov 08, 2017 (151)
64	GRF	ss2701866123	Nov 08, 2017 (151)
65	GNOMAD	ss2946039701	Nov 08, 2017 (151)
66	SWEGEN	ss3014946019	Nov 08, 2017 (151)
67	BIOINF_KMB_FNS_UNIBA	ss3028264044	Nov 08, 2017 (151)
68	CSHL	ss3351576025	Nov 08, 2017 (151)
69	ILLUMINA	ss3627587543	Oct 12, 2018 (152)
70	ILLUMINA	ss3631338181	Oct 12, 2018 (152)
71	ILLUMINA	ss3636346858	Oct 12, 2018 (152)
72	ILLUMINA	ss3638140609	Oct 12, 2018 (152)
73	ILLUMINA	ss3639081519	Oct 12, 2018 (152)
74	ILLUMINA	ss3639849611	Oct 12, 2018 (152)
75	ILLUMINA	ss3641972670	Oct 12, 2018 (152)
76	ILLUMINA	ss3643120582	Oct 12, 2018 (152)
77	ILLUMINA	ss3643899236	Oct 12, 2018 (152)
78	URBANLAB	ss3650566086	Oct 12, 2018 (152)
79	ILLUMINA	ss3652145949	Oct 12, 2018 (152)
80	ILLUMINA	ss3653849847	Oct 12, 2018 (152)
81	EGCUT_WGS	ss3681930008	Jul 13, 2019 (153)
82	EVA_DECODE	ss3699785087	Jul 13, 2019 (153)
83	ACPOP	ss3741739512	Jul 13, 2019 (153)
84	EVA	ss3754266446	Jul 13, 2019 (153)
85	PACBIO	ss3788109070	Jul 13, 2019 (153)
86	PACBIO	ss3793080978	Jul 13, 2019 (153)
87	PACBIO	ss3797966168	Jul 13, 2019 (153)
88	KHV_HUMAN_GENOMES	ss3819540076	Jul 13, 2019 (153)
89	EVA	ss3834702170	Apr 27, 2020 (154)
90	EVA	ss3840958118	Apr 27, 2020 (154)
91	EVA	ss3846451431	Apr 27, 2020 (154)
92	HGDP	ss3847554207	Apr 27, 2020 (154)
93	SGDP_PRJ	ss3884997668	Apr 27, 2020 (154)
94	KRGDB	ss3934548517	Apr 27, 2020 (154)
95	KOGIC	ss3978098557	Apr 27, 2020 (154)
96	EVA	ss3985773102	Apr 26, 2021 (155)
97	TOPMED	ss5024688753	Apr 26, 2021 (155)
98	TOMMO_GENOMICS	ss5220789051	Apr 26, 2021 (155)
99	1000G_HIGH_COVERAGE	ss5301891556	Oct 17, 2022 (156)
100	EVA	ss5315859776	Oct 17, 2022 (156)
101	EVA	ss5425435657	Oct 17, 2022 (156)
102	HUGCELL_USP	ss5495143518	Oct 17, 2022 (156)
103	1000G_HIGH_COVERAGE	ss5605020821	Oct 17, 2022 (156)
104	SANFORD_IMAGENETICS	ss5659423499	Oct 17, 2022 (156)
105	TOMMO_GENOMICS	ss5776150333	Oct 17, 2022 (156)
106	YY_MCH	ss5816199317	Oct 17, 2022 (156)
107	EVA	ss5846774595	Oct 17, 2022 (156)
108	EVA	ss5851677261	Oct 17, 2022 (156)
109	EVA	ss5900164334	Oct 17, 2022 (156)
110	EVA	ss5950840106	Oct 17, 2022 (156)
111	1000Genomes	NC_000016.9 - 84448621	Oct 12, 2018 (152)
112	1000Genomes_30x	NC_000016.10 - 84415015	Oct 17, 2022 (156)
113	The Avon Longitudinal Study of Parents and Children	NC_000016.9 - 84448621	Oct 12, 2018 (152)
114	Chileans	NC_000016.9 - 84448621	Apr 27, 2020 (154)
115	Genome-wide autozygosity in Daghestan	NC_000016.8 - 83006122	Apr 27, 2020 (154)
116	Genetic variation in the Estonian population	NC_000016.9 - 84448621	Oct 12, 2018 (152)
117	The Danish reference pan genome	NC_000016.9 - 84448621	Apr 27, 2020 (154)
118	gnomAD - Genomes Submission ignored due to conflicting rows: Row 497333003 (NC_000016.10:84415014:T:A 11/139884) Row 497333004 (NC_000016.10:84415014:T:C 76286/139816)	-	Apr 26, 2021 (155)
119	gnomAD - Genomes Submission ignored due to conflicting rows: Row 497333003 (NC_000016.10:84415014:T:A 11/139884) Row 497333004 (NC_000016.10:84415014:T:C 76286/139816)	-	Apr 26, 2021 (155)
120	Genome of the Netherlands Release 5	NC_000016.9 - 84448621	Apr 27, 2020 (154)
121	HGDP-CEPH-db Supplement 1	NC_000016.8 - 83006122	Apr 27, 2020 (154)
122	HapMap	NC_000016.10 - 84415015	Apr 27, 2020 (154)
123	KOREAN population from KRGDB	NC_000016.9 - 84448621	Apr 27, 2020 (154)
124	Korean Genome Project	NC_000016.10 - 84415015	Apr 27, 2020 (154)
125	Northern Sweden	NC_000016.9 - 84448621	Jul 13, 2019 (153)
126	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000016.9 - 84448621	Apr 26, 2021 (155)
127	Qatari	NC_000016.9 - 84448621	Apr 27, 2020 (154)
128	SGDP_PRJ	NC_000016.9 - 84448621	Apr 27, 2020 (154)
129	Siberian	NC_000016.9 - 84448621	Apr 27, 2020 (154)
130	8.3KJPN	NC_000016.9 - 84448621	Apr 26, 2021 (155)
131	14KJPN	NC_000016.10 - 84415015	Oct 17, 2022 (156)
132	TopMed	NC_000016.10 - 84415015	Apr 26, 2021 (155)
133	UK 10K study - Twins	NC_000016.9 - 84448621	Oct 12, 2018 (152)
134	A Vietnamese Genetic Variation Database	NC_000016.9 - 84448621	Jul 13, 2019 (153)
135	ALFA	NC_000016.10 - 84415015	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs56536626	May 24, 2008 (130)
rs58245233	May 24, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss2946039701	NC_000016.9:84448620:T:A	NC_000016.10:84415014:T:A	(self)
4680623636, ss2214362843	NC_000016.10:84415014:T:A	NC_000016.10:84415014:T:A	(self)
193547, 232099, ss76616225, ss90480824, ss109531233, ss160271529, ss168619126, ss171654447, ss202024484, ss207589343, ss211752772, ss282634603, ss287121340, ss291894151, ss483573642, ss1397723616, ss1696810940, ss1713559670, ss3639081519, ss3639849611, ss3643120582, ss3643899236, ss3847554207	NC_000016.8:83006121:T:C	NC_000016.10:84415014:T:C	(self)
70513519, 39127402, 174870, 27668256, 4235294, 17441586, 41725911, 15024377, 999029, 18244970, 37014648, 9847582, 78758358, 39127402, 8670836, ss227385493, ss237127877, ss243448074, ss480302747, ss483878645, ss536073687, ss565072472, ss660850348, ss780442533, ss782382931, ss832729882, ss833320712, ss835932254, ss992769303, ss1080827630, ss1357318477, ss1427929025, ss1578027664, ss1635000839, ss1677994872, ss1808634360, ss1936203048, ss1968321485, ss2028892789, ss2095070186, ss2157331228, ss2628936817, ss2633353909, ss2701866123, ss2946039701, ss3014946019, ss3351576025, ss3627587543, ss3631338181, ss3636346858, ss3638140609, ss3641972670, ss3652145949, ss3653849847, ss3681930008, ss3741739512, ss3754266446, ss3788109070, ss3793080978, ss3797966168, ss3834702170, ss3840958118, ss3884997668, ss3934548517, ss3985773102, ss5220789051, ss5315859776, ss5425435657, ss5659423499, ss5846774595, ss5950840106	NC_000016.9:84448620:T:C	NC_000016.10:84415014:T:C	(self)
92546756, 1434286, 34476558, 109987437, 240234414, 4680623636, ss2214362843, ss3028264044, ss3650566086, ss3699785087, ss3819540076, ss3846451431, ss3978098557, ss5024688753, ss5301891556, ss5495143518, ss5605020821, ss5776150333, ss5816199317, ss5851677261, ss5900164334	NC_000016.10:84415014:T:C	NC_000016.10:84415014:T:C	(self)
ss23510612, ss43818832, ss67007610, ss67326902, ss68129378, ss69353256, ss70568565, ss71108880, ss75579877, ss85222028, ss96703929, ss136858914, ss153198906, ss157664075, ss159217487, ss161814109, ss172085753	NT_010498.15:38062819:T:C	NC_000016.10:84415014:T:C	(self)
ss19343803	NT_024797.14:11160471:T:C	NC_000016.10:84415014:T:C	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

1 citation for rs12446219

PMID	Title	Author	Year	Journal
35237725	Factors in the neurodevelopment of negative urgency: Findings from a community-dwelling sample.	Evans CL et al.	2022	Brain and neuroscience advances

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs12446219