| Vpu | activates | caspase 3 preproprotein  |
| binds | beta-transducin repeat containing protein isoform 2 |
| degrades | CD4 antigen precursor |
| downregulates | BCL2-like 1 isoform 1 |
| | BCL2-related protein A1 |
| | CD4 antigen precursor |
| | major histocompatibility complex, class I, A precursor |
| | major histocompatibility complex, class I, B |
| | major histocompatibility complex, class I, C precursor |
| | TNF receptor-associated factor 1 |
| inhibited by | CD4 antigen precursor |
| inhibits | beta-transducin repeat containing protein isoform 2 |
| | nuclear factor kappa-B, subunit 1 |
| interacts with | FBXW11: F-box and WD-40 domain protein 11; beta-transducin repeat-containing protein 2 |
| | potassium channel, subfamily K, member 3 |
| | small glutamine-rich tetratricopeptide |
| | tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor |
| phosphorylated by | casein kinase 2, alpha prime polypeptide |
| | casein kinase 2, beta polypeptide |
| | casein kinase II alpha 1 subunit isoform a |
| recruits | beta-transducin repeat containing protein isoform 2 |
| regulates | CD4 antigen precursor |
| stabilizes | activating transcription factor 4 |
| | catenin (cadherin-associated protein), beta 1, 88kDa |
| | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| upregulates | CD40 antigen isoform 1 precursor |
| | vascular cell adhesion molecule 1 isoform a precursor |
