| Env, gp160 | activates | alpha 1 type IV collagen preproprotein  |
| | alpha 2 type IV collagen preproprotein  |
| | alpha 3 type IV collagen isoform 1 precursor  |
| | alpha 4 type IV collagen precursor  |
| | c-K-ras2 protein isoform a  |
| | COL4A5: collagen, type IV, alpha 5 (Alport syndrome)  |
| | jun oncogene  |
| | lymphocyte-specific protein tyrosine kinase precursor  |
| | mitogen-activated protein kinase 1  |
| | mitogen-activated protein kinase 10 isoform 1  |
| | mitogen-activated protein kinase 14 isoform 1  |
| | mitogen-activated protein kinase 3 isoform 1  |
| | mitogen-activated protein kinase 8 isoform JNK1 alpha1  |
| | mitogen-activated protein kinase 9 isoform JNK2 alpha2  |
| | neuroblastoma RAS viral (v-ras) oncogene homolog  |
| | phosphoinositide-3-kinase, catalytic, alpha polypeptide  |
| | phosphoinositide-3-kinase, catalytic, beta polypeptide  |
| | phosphoinositide-3-kinase, catalytic, delta polypeptide  |
| | phosphoinositide-3-kinase, catalytic, gamma polypeptide  |
| | phosphoinositide-3-kinase, class 2, alpha polypeptide  |
| | phosphoinositide-3-kinase, class 2, beta polypeptide  |
| | phosphoinositide-3-kinase, class 2, gamma polypeptide  |
| | phosphoinositide-3-kinase, class 3  |
| | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)  |
| | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 isoform 1  |
| | small GTPase protein E-Ras  |
| | v-fos FBJ murine osteosarcoma viral oncogene homolog  |
| | v-Ha-ras Harvey rat sarcoma viral oncogene homolog isofrom 1  |
| associates with | major histocompatibility complex, class II, DM alpha precursor  |
| | major histocompatibility complex, class II, DM beta precursor  |
| | major histocompatibility complex, class II, DO alpha precursor  |
| | major histocompatibility complex, class II, DO beta precursor  |
| | major histocompatibility complex, class II, DP alpha 1 precursor  |
| | major histocompatibility complex, class II, DP beta 1 precursor  |
| | major histocompatibility complex, class II, DQ alpha 1 precursor  |
| | major histocompatibility complex, class II, DQ alpha 2  |
| | major histocompatibility complex, class II, DQ beta 1 precursor  |
| | major histocompatibility complex, class II, DQ beta 2  |
| | major histocompatibility complex, class II, DR alpha precursor  |
| | major histocompatibility complex, class II, DR beta 1 precursor  |
| | major histocompatibility complex, class II, DR beta 3 precursor  |
| | major histocompatibility complex, class II, DR beta 4 precursor  |
| | major histocompatibility complex, class II, DR beta 5 precursor  |
| binds | calmodulin 1  |
| | calmodulin 2  |
| | calmodulin 3  |
| | calnexin precursor  |
| | calreticulin precursor  |
| | CD4 antigen precursor  |
| | FETUB: fetuin B  |
| | fibronectin 1 isoform 1 preproprotein  |
| | major histocompatibility complex, class I, A precursor  |
| cleaved by | furin preproprotein  |
| | L-plastin  |
| | PCSK1: proprotein convertase subtilisin/kexin type 1  |
| | PCSK6: PACE4, proprotein convertase subtilisin/kexin type 6  |
| | proprotein convertase subtilisin/kexin type 5 preproprotein  |
| | proprotein convertase subtilisin/kexin type 7 preproprotein  |
| co-localizes with | cytotoxic T-lymphocyte-associated protein 4 isoform a precursor  |
| complexes with | CD4 antigen precursor  |
| decreases phosphorylation of | BCL2-antagonist of cell death protein  |
| | protein-tyrosine kinase fyn isoform a  |
| downregulated by | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha  |
| downregulates | B-cell lymphoma protein 2 alpha isoform  |
| | CD4 antigen precursor  |
| | integrin alpha L precursor  |
| | interferon, gamma  |
| | interleukin 2 precursor  |
| | tumor necrosis factor alpha  |
| inactivates | c-K-ras2 protein isoform a  |
| | neuroblastoma RAS viral (v-ras) oncogene homolog  |
| | small GTPase protein E-Ras  |
| | v-Ha-ras Harvey rat sarcoma viral oncogene homolog isofrom 1  |
| induces phosphorylation of | vav 1 oncogene  |
| | vav 2 oncogene  |
| | vav 3 oncogene isoform 1  |
| | zeta-chain associated protein kinase 70kDa isoform 1  |
| induces release of | cytochrome c  |
| | tumor necrosis factor alpha  |
| inhibited by | catalase  |
| | manganese superoxide dismutase isoform A precursor  |
| | superoxide dismutase 1, soluble  |
| | superoxide dismutase 3, extracellular precursor  |
| inhibits | integrin alpha L precursor  |
| | mitogen-activated protein kinase 1  |
| | mitogen-activated protein kinase 10 isoform 1  |
| | mitogen-activated protein kinase 8 isoform JNK1 alpha1  |
| | mitogen-activated protein kinase 9 isoform JNK2 alpha2  |
| | phosphoinositide-3-kinase, catalytic, alpha polypeptide  |
| | phosphoinositide-3-kinase, catalytic, beta polypeptide  |
| | phosphoinositide-3-kinase, catalytic, delta polypeptide  |
| | phosphoinositide-3-kinase, catalytic, gamma polypeptide  |
| | phosphoinositide-3-kinase, class 2, alpha polypeptide  |
| | phosphoinositide-3-kinase, class 2, beta polypeptide  |
| | phosphoinositide-3-kinase, class 2, gamma polypeptide  |
| | phosphoinositide-3-kinase, class 3  |
| | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)  |
| | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 isoform 1  |
| | phospholipase C gamma 1 isoform a  |
| interacts with | BCL2-like 1 isoform 1  |
| | CD28 antigen  |
| | CD4 antigen precursor  |
| | CR2: complement component (3d/Epstein Barr virus) receptor 2 isoform 1  |
| | heat shock 70kDa protein 5  |
| | integrin alpha L precursor  |
| | intercellular adhesion molecule 1 precursor  |
| | interleukin 12A precursor  |
| | interleukin 12B precursor  |
| | interleukin 7 precursor  |
| | lymphocyte-specific protein tyrosine kinase precursor  |
| | major histocompatibility complex, class I, A precursor  |
| | major histocompatibility complex, class I, B  |
| | major histocompatibility complex, class I, C precursor  |
| | major histocompatibility complex, class I, E precursor  |
| | major histocompatibility complex, class I, F precursor  |
| | major histocompatibility complex, class I, G precursor  |
| | major histocompatibility complex, class II, DR alpha precursor  |
| | major histocompatibility complex, class II, DR beta 1 precursor  |
| | major histocompatibility complex, class II, DR beta 3 precursor  |
| | major histocompatibility complex, class II, DR beta 4 precursor  |
| | major histocompatibility complex, class II, DR beta 5 precursor  |
| | NADPH oxidase 1 isoform long  |
| | NOX3: NADPH oxidase 3  |
| | NOX4: NADPH oxidase 4  |
| | NOX5: NADPH oxidase, EF-hand calcium binding domain 5  |
| | protein kinase C, alpha  |
| | protein kinase C, beta isoform 1  |
| | protein kinase C, delta  |
| | protein kinase C, epsilon  |
| | protein kinase C, eta  |
| | protein kinase C, gamma  |
| | protein kinase C, iota  |
| | protein kinase C, theta  |
| | protein kinase C, zeta isoform 1  |
| | secreted frizzled-related protein 1  |
| | serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1  |
| | SLC3A2: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 isoform a, CD98 heavy chain  |
| | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5  |
| | transforming growth factor, beta 1  |
| | tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor  |
| methylated by | HMT1 hnRNP methyltransferase-like 6  |
| palmitoylated by | CPT1A: carnitine palmitoyltransferase 1A isoform 1 (liver)  |
| | CPT1B: carnitine palmitoyltransferase 1B (muscle)  |
| | CPT1C: carnitine palmitoyltransferase 1C  |
| | CPT2: carnitine palmitoyltransferase II  |
| processed by | angiotensin I converting enzyme isoform 1 precursor  |
| | B3GALNT1: beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)  |
| | B3GALT1: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1  |
| | B3GALT2: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2  |
| | B3GALT4: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4  |
| | B3GALT5: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5  |
| | B4GALT2: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2  |
| | B4GALT3: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3  |
| | B4GALT4: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4  |
| | B4GALT6: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6  |
| | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4  |
| | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5  |
| | CHST10: carbohydrate sulfotransferase 10  |
| | CHST1: carbohydrate (keratan sulfate Gal-6) sulfotransferase 1  |
| | CHST2: carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2  |
| | CHST3: carbohydrate (chondroitin 6) sulfotransferase 3  |
| | CHST6: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6  |
| | CHST7: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7  |
| | CHST8: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8  |
| | CHST9: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9  |
| | FUT8: fucosyltransferase 8 (alpha (1,6) fucosyltransferase)  |
| | GAA: glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)  |
| | GANAB: glucosidase, alpha; neutral AB isoform 2  |
| | GANC: glucosidase, alpha; neutral C  |
| | GBA2: glucosidase, beta (bile acid) 2  |
| | GBA3: glucosidase, beta, acid 3 (cytosolic)  |
| | GCS1: glucosidase I  |
| | MAN1A1: mannosidase, alpha, class 1A, member 1  |
| | MAN1A2: mannosidase, alpha, class 1A, member 2  |
| | MAN1B1: mannosidase, alpha, class 1B, member 1  |
| | MAN1C1: mannosidase, alpha, class 1C, member 1  |
| | MAN2A1: mannosidase, alpha, class 2A, member 1  |
| | MAN2A2: mannosidase, alpha, class 2A, member 2  |
| | MAN2B1: mannosidase, alpha, class 2B, member 1  |
| | MAN2B2: mannosidase, alpha, class 2B, member 2  |
| | MANBA: mannosidase, beta A, lysosomal  |
| | MANEA: mannosidase, endo-alpha  |
| | mannosidase, alpha, class 2C, member 1  |
| | MGAT2: mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  |
| | MGAT4A: mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A  |
| | MGAT4B: mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B  |
| | MGAT4C: mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)  |
| | MGAT5B: mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B  |
| | ST3GAL1: ST3 beta-galactoside alpha-2,3-sialyltransferase 1  |
| | ST3GAL2: ST3 beta-galactoside alpha-2,3-sialyltransferase 2  |
| | ST3GAL3: ST3 beta-galactoside alpha-2,3-sialyltransferase 3  |
| | ST3GAL4: ST3 beta-galac |