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The NCBI Malaria Genetics & Genomics Website is provided as a service to the malaria community in support of the Malaria Genome Project. P.f. Genome Sequencing Consortium Data Release Policy NCBI Malaria Data Release Policy Sequencing Center Acknowledgement Malaria Genome Sequence Tag Project P.f. Genome Sequencing Consortium Data Release Policy The Malaria Genome Project has been undertaken by an international consortium of scientists and funding agencies. The goal of the project is to produce the sequence of the genome of the human malaria parasite Plasmodium falciparum (clone 3D7). The project work in the USA is funded by The National Institute of Allergy and Infectious Disease, The Burroughs Wellcome Fund and the US Department of Defense. The project work in the UK is funded by The Wellcome Trust. High-throughput DNA sequencing and genome analysis is ongoing in three centers: The Institute for Genomic Research / Naval Medical Research Institute (U.S.A.), The Sanger Centre (U.K.) and Stanford University (U.S.A.). Additional investigators at other sites are contributing to the goal of the project by, for example, developing alternative methods of library construction, producing genetic and physical maps, and developing databases and bioinformatics resources. In parallel, informatics personnel at the National Center for Biotechnology Information are developing a general Malaria Website to facilitate common access to the sequence and other relevant information on malaria. The scientists participating in the Malaria Genome Project have agreed to release P.falciparum sequence information (raw shotgun reads and assembled contigs in progress ) as rapidly as possible as a resource for the entire malaria research community. These data releases do not constitute scientific publication, but rather aid investigators with information to expedite biological experimentation. In fact, these data are preliminary and may contain errors and possible contamination from other species, e.g. yeast and E.coli. It is anticipated that the P.falciparum sequence data will assist colleagues in their research, particularly in the search for genes and the studies of the genes' biological functions. Colleagues are encouraged to share their results with the members of these genome centers in order to achieve the optimal annotation of the P.falciparum genome. NCBI Malaria Data Release Policy The data used for this website were submitted to the Sequence Databases (NCBI/EMBL/DDBJ) from the Plasmodium falciparum sequencing centers: Sanger Center, Stanford, and TIGR or downloaded from the sequencing center's FTP sites. Investigators using data from this site should read and follow the respective sequencing center's data release policy.
Investigators should acknowledge the appropriate sequencing center as the source of the information in all relevant publications by including the appropriate sentences in both the Materials and Methods and Acknowledgement sections: Sequencing Center Acknowledgement Sanger Acknowledgement: "Sequence data for P. falciparum chromosome (1,3,4,5,6,7,8,9,13) was obtained from The Sanger Centre website at http://www.sanger.ac.uk/Projects/P_falciparum/. Sequencing of P.falciparum chromosome (1,3,4,5,6,7,8,9,13) was accomplished as part of the Malaria Genome Project with support by The Wellcome Trust." Stanford Acknowledgement: "Sequence data for P.falciparum chromosome 12 was obtained from the Stanford DNA Sequencing and Technology Center website at http://www-sequence.stanford.edu/group/malaria. Sequencing of P.falciparum chromosome 12 was accomplished as part of the Malaria Genome Project with support by the Burroughs Wellcome Fund". TIGR/NMRC Acknowledgement: "Preliminary sequence data for P. falciparum chromosome (2,10,11,14) was obtained from The Institute for Genomic Research website (www.tigr.org). Sequencing of chromosome (2,10,11,14) was part of the International Malaria Genome Sequencing Project and was supported by awards from the Burroughs Wellcome Fund and the U.S. Department of Defense." Note: The Chromosome 2 Sequencing Project was a collaborative effort by The Institute of Genomic Research (TIGR) and the Naval Medical Research Center (NMRC). So, for chromosome 2 replace all instances of TIGR with TIGR/NMRC. Malaria Genome Sequence Tag Project "Data release policy: We are releasing the P. berghei and P. vivax sequence information as rapidly as possible as a resource for the entire malaria research community. These data do not constitute scientific publication. These data are preliminary and may contain errors and possible contamination from other species, especially host DNA and E.coli, although we have screened for these as far as possible. It is anticipated that the Plasmodium sequence data will assist colleagues in their research, particularly in the search for genes and the studies of the genes' biological functions. Colleagues are encouraged to share their results with us. Investigators using the sequence data from this Website should acknowledge the source of the information in all relevant publications by including the following sentences in both the Materials and Methods and Acknowledgments sections: "Sequence data for P. vivax / berghei / falciparum was obtained from the University of Florida Gene Sequence Tag Project Website at: http://parasite.vetmed.ufl.edu Funding was provided by the National Institute of Allergy and Infectious Diseases (for P. berghei and P. vivax data) / University of Florida Division of Sponsored Research and the Burroughs Wellcome Fund (for P. falciparum data)." We plan to publish details of these sequences in a peer-reviewed journal as soon as possible. Permission of the Principal Investigator or Project Coordinator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale."
The sequencing centers plan on publishing the completed and annotated sequence in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. The annotation data provided by NCBI do not constitute scientific publications of the Plasmodium falciparum sequences, but rather serve to expedite malaria research. The annotations are based on provisional sequence data obtained from the sequencing centers. They should not be construed as definitive nor as a replacement of the annotated sequences by the sequencing centers (Sanger, Stanford, TIGR), but rather an independent computationally derived annotation of the sequence data. Last updated: Feb 15, 2000 |