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Marker
Segregation Table Legend: |
This page includes:
A brief description of the table column titles
and any associated comments is displayed below.
| Column |
Description and
Notes |
| Marker |
Unique marker name. Mostly microsatellite
markers developed from simple repeats in genomic sequences from
GenBank or the Malaria Genome Sequencing Centers, or screened de
novo from genomic libraries. Some markers were screened as RFLPs.
Almost all markers may be used as Sequence-Tagged Sites (see under
'dbSTS no." below). |
| Synonym |
A synonym |
| dbSTS no. |
STS marker accession number. You may view the marker
record, including primer sequence by clicking on the accession number. |
| GenBank no. |
GenBank Accession no. for markers that are part of
sequences in GenBank |
| Position |
Position assignment on the genetic linkage map. Markers
for which position is blank could not be unequivocally placed. |
| Framework |
Lod Score Confidence Level:
3: Lod >= 1.7;
2: LOD >= 1.0;
1: LOD >= 0.01 |
| Chromosome |
The chromosome the markers were assigned |
| Forward/Reverse Primers |
The DNA sequence of the forward and reverse primers
used in the experiment. The forward primer is listed first. (Available
on PDF-Printable Version only) |
| Size (bp) |
The marker size, in base pairs, given
either for the Dd2 allele or for the GenBank sequence if an accession
number is listed. (Available on PDF-Printable Version only) |
| H |
HB3 genotype (green) |
| D |
Dd2 genotype (aqua) |
| H* |
D* |
* for third allele. H* is the third allele
from HB3 parent and D* is the third allele from Dd2 parent. Note:
* indicate non-canonical alleles from spontaneous microsatllite
mutations in the parental populations. |
| |
Gene conversion candidate. A gene conversion
is a non-reciprocal process of genetic change in which one DNA sequence
directs the conversion of a different, usually homologous, DNA partner
to its own sequence. In meiotic gene conversion, one allele of a
pair is changed to the sequence of its partner. This is a distinct
process from reciprocal chromatid exchange. |
| |
Empty allele or no PCR product; Amplified HB3 band
is present, but Dd2 band is not present. |
Reference:
Su X., Ferdig M., Huang Y., Huynh CQ., Liu A., You J., Wootton JC.,
Wellems T.E. (1999). A Genetic Map and Recombination Parameters of the
Human Malaria Parasite Plasmodium falciparum. Science
286(5443): 1351-3. PubMed
Su X., and Wellems T. E. (1996). Toward a High-Resolution Plasmodium
falciparum Linkage Map: Polymorphic Markers from Hundreds of Simple
Sequence Repeats. Genomics 33, 430-444. PubMed
Last updated: Nov 15, 1999
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