PMC

Hyper-reactivity in the fusiform gyrus during processing of fearful over neutral faces in patients with social anxiety disorder as compared with healthy controls (axial plane at z –20). The colorbar indicates t-values.

Changes in fusiform gyrus connectivity in patients with social anxiety disorder (SAD) compared with healthy controls (HC) during processing of fearful over neutral faces. The fusiform showed greater connectivity (SAD>HC) with the amygdala (left, coronal plane at y=−7; illustrative P-threshold of P<0.05 uncorrected) and less connectivity (SAD<HC) with the ventromedial prefrontal cortex (vmPFC; right, sagittal plane at x=−3; illustrative P-threshold of P<0.005). The colorbar indicates t-values. The graphs display extracted measures of connectivity. Error bars represent s.e.m.