Recombination Rates across the 22q11.2 Region
(A) Position of the LCRs, or SDs, spanning the 22q11.2 region, as well as a snapshot of the representative genes and LCRs, or SDs, from the UCSC Genome Browser (hg19) for the same interval as shown in B for the purpose of orientation.
(B) Recombination rates (cM/Mb) across the 22q11.2 region. The recombination rates were taken from UCSC Genome Browser (hg19) tracks (Marshfield, deCODE, and Genethon), which indicate their source of origin. They were derived from the same region shown in A. The color coding represents recombination rate: black represents the highest rates, and light gray represents the lowest rates. The female and male averages include data from all three studies. The ratios of the average female-to-male recombination rates (Fem/Male Ratio) are shown across the region.
(C) The genetic distance and recombination rate across the 22q11.2 region (UCSC Genome Browser hg19). Data were obtained from Kong et al., 2010. The female and male genetic distances, as well as the most centromeric and telomeric SNPs, with respect to chromosome 22 are indicated. The female-to-male genetic-distance ratio (Fem/Male) is 2.31 for 22q11.2 and 1.46 for all of chromosome 22.