PMC

Figure 1. T-cell epitope specific reactivity in TILs. The illustration shows the distribution of the described T-cell epitopes of relevance for melanoma into four different antigen classes: Cancer-testis, Differentiation, Mutation, and Overexpressed antigens; and the distribution of the CD8⁺ T-cell responses found in TILs from 15 patients into the same four antigen-classes. An obvious caveat relates to the HLA-restriction of the different epitopes as this patient cohort where non-selected for HLA-expression.