PMC

41-year-old woman with primary malignant melanoma of anterior mediastinum. Enhanced axial CT image shows heterogeneously enhancing mass involving anterior mediastinum, displacing great vessels and heart to left side.

45-year-old man with primary malignant melanoma of anterior mediastinum.
A-C. Enhanced axial CT images show huge, lobulating-contoured mediastinal mass with pericardial effusion, pericardial nodules, and pleural effusion in left hemithorax. D. Photomicrograph of histologic specimen shows melanocytes with pleomorphic nuclei and brownish pigment (hematoxylin and eosin stain, × 400).