PMC

An overview of the canonical WNT signaling pathway. Genes highlighted in this paper as implicated in OSCC are shaded grey. Gene interactions are shown as activating (arrows) or inhibiting (blocked arrows). Boxes indicate processes that will ultimately be influenced by WNT signaling. Solid lines represent direct interactions and dashed lines indicate indirect effects. Lines connecting genes represent binding or association interactions. Complexes are represented by ovals that overlap.