PMC

Representative FTIRI mineral:matrix ratio images and corresponding pixel histograms listed with mean and full width at half maximum (FWHM) values for the Gaussian curves fit to each distribution for cortical bone at the (a) iliac crest, (b) greater trochanter, and (c) subtrochanteric femur.

FTIR parameter distribution (a) means and (b) full widths at half maximum (FWHM) for cortical bone from each of the 10 donors. Values have been normalized to those at the iliac crest for each donor to facilitate visual comparison across sites. Missing bars indicate that the tissue type was not present in the biopsy.

FTIR parameter distribution (a) means and (b) full widths at half maximum (FWHM) for trabecular bone from each of the 10 donors. Values have been normalized to those at the iliac crest for each donor to facilitate visual comparison across sites. Missing bars indicate that the tissue type was not present in the biopsy.

FTIR parameter distribution (a) means and (b) full widths at half maximum averaged over the 10 donors for 3 anatomic sites: iliac crest (IC) greater trochanter (GT), and subtrochanteric femur (ST). Error bars indicate standard deviations. * p < 0.05 vs. IC, ** p < 0.05 vs. GT, ^ p < 0.1 vs. IC, ^^ p < 0.1 vs. GT. (Sample sizes for each tissue type and site: Cortical IC 10, ST 9, GT 9; Trabecular IC 9, GT 9, ST 3.)