Map of the study area of the Monzino 80-plus Study: A. Europe, Italy (in grey) and, within the borders of the Lombardy region, the province of Varese (in black). B. The study area: the province of Varese (in grey) and the area of the eight municipalities initially investigated: in red Gallarate and in orange the seven municipalities of the lower Olona valley (Fagnano Olona, Gorla Maggiore, Solbiate Olona, Gorla Minore, Olgiate Olona, Marnate, and Castellanza)