PMC

Bar graph depicting region of interest (ROI) volumes of all subjects with autism compared to all controls regardless of head size. Percentages were calculated identically to that reported by as follows: (mean autistic volume)/(mean control volume) × 100. Values >100 indicate the region is larger in the autism group; values <100 represent larger volumes in the control group. Adjusted and unadjusted volume comparisons are denoted according to the legend inset. This figure should be compared to of , p. 1186).

Voxel based morphology (VBM) findings depict few differences in white matter (WM) pixel concentration as shown in the “glass” brain model, where age and IQ were control variables. The arrow points to the region of greatest difference, which was in the right temporal stem as shown in the coronal image in the lower right, which actually showed less WM pixel concentration in the autism subjects. It should be noted that as a result of technical issues and image registration and analysis using the VBM method, two autism subjects, both normocephalic and four control subjects (3 normocephalic, 1 reading disorder [RD]).