Efficacy of therapeutic agents in PC3 xenograft mouse models following vehicle (solid circle), docetaxel (solid square), thalidomide (solid triangle), or bevacizumab (inverted solid triangle) alone; a dual combination of docetaxel and thalidomide (solid diamond), docetaxel and bevacizumab (open circle), thalidomide and bevacizumab (open square); and a combination of docetaxel, thalidomide, and bevacizumab (open triangle). Values are means from five to eight mice. Doc, docetaxel; Thal, thalidomide; BV, bevacizumab.