It must be noted that the overall group of alcoholic patients was enrolled with an admission diagnosis of alcoholic psychosis. Although alcoholic hepatitis was not an enrollment criterion, these subjects undoubtedly had some degree of mild ethanol-induced liver injury as all subjects had at least one abnormal liver chemistry test. However, a subgroup analysis was performed to evaluate in patients with biochemically well-characterized alcoholic hepatitis. Alcoholic subjects were selected with AST and ALT greater than 30 and AST to ALT ratio greater than one. These selection criteria identified 26 subjects, 13 from each of the two treatment groups. There were no statistically significant differences in liver enzymes between treatment groups at day one. A paired t-test was performed before (day 1) and after (day 7) therapy (). Probiotic therapy was associated with a significant decrease in ALT (58.08 vs. 37.46 U/L), AST (137.5 vs. 56.38 U/L), GGT (156.9 vs. 135.3 U/L), LDH (500.4 vs. 362.6 U/L), and total bilirubin (20.10 vs. 12.74 μmol/L). While standard therapy was associated with a significant decrease in AST (183.60 vs. 88.54 U/L) and total bilirubin (24.54 vs. 10.89 μmol/L); ALT, GGT, and LDH were unchanged. Intergroup comparison revealed a significant mean ALT reduction in the probiotic therapy group (30.03±5.64 % decrease) vs. the standard therapy group (9.15±15.08 % increase, p=0.013). depicts the paired analysis of these ALT data. These data demonstrate that probiotic therapy is associated with a greater improvement in liver enzymes than standard therapy alone in patients with mild ethanol induced liver injury / alcoholic hepatitis.