PMC

Figure 1 Flowchart of patient decision algorithm
The pre–magnetic source imaging (MSI) decision was blinded to MSI. The patients were assigned to one of three treatments. The blind was then broken, and the MSI information was presented. Then a post-MSI decision was made, and the patients were reassigned to one of three treatments. The post-MSI treatments are primed. One-third of the patients were reassigned to a different treatment by the post-MSI decision. VEEG = video-EEG; ICEEG = intracranial EEG; VNS = vagal nerve stimulation.

Figure 2 Patient 33: MSI added information to ICEEG
These figures show the actual magnetic source imaging (MSI) data presented at the conferences. (A) First MSI, before intracranial EEG (ICEEG) and before first surgery. The MSI shows a cluster of spike dipoles in the right prefrontal region. MRI in top row: Left to right: Axial, coronal, and sagittal images. Bottom left: Typical spike in MEG. Calibrations: 10 pT, 270 msec. Bottom right: Isocontour maps and butterfly plot of tracings: Blue magnetic flux exiting head, red magnetic flux entering head. MRIs are radiology convention (with left at right of image); spike tracings and MEG map are electrophysiology convention (left at left). (B) Second MSI 18 months later, after first ICEEG and first surgery of right anterior temporal lobectomy (visible on sagittal section), but before second ICEEG and second surgery of right frontal resection. MSI shows similar cluster of spike dipoles in right prefrontal region. Figure setup same as in A. Calibrations: 12 pT, 404 msec.