PMC

a) Nucleotide sequence of Bm17DIII and its homologs in W. bancrofti, O. volvulus and L. loa. Top sequence data shows DNA sequences of Bm17DIII and its homologs in W. bancrofti, O. volvulus and L. loa. b) Amino acid sequence of BmR1 and its homologs in W. bancrofti, O. volvulus and L. loa. Bottom sequence data shows amino acid sequence of BmR1 and its homologs in W. bancrofti (Wb-BmR1), O. volulus (Ov-BmR1) and L. loa (Ll-BmR1). Comparison between Bm17DIII DNA sequence and its DNA homologs in O. volvulus and L. loa showed only two bases difference at 98 and 483. BmR1 homologs of the amino acid sequence was identical with W. bancrofti. However, with O. volvulus and L. loa a difference occurred only at one amino acid coded by bases 97–99 i.e. a change from Ile (ATC) to Thr (ACC).