Haplotype analysis in French Canadian families with PDB (common, DD, PT, CT, and GE families) and allele combinations of informative sporadic cases (UN096, UN054, UN070, and UN010). Markers are indicated on the left, with the 1215C→T mutation and two informative SNPs at position 916 and 976 in the coding region of SQSTM1/p62. The marker order is based on haplotype analysis of 24 families (379 individuals), allowing the lower level of recombination. Shared haplotypes are represented by vertical black bars (PDB3H1) or are boxed (PDB3H2). Because haplotypes of sporadic cases could not be determined, both alleles for heterozygotic markers are depicted.