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Select item 90076301.

Expression of Foxp3 by T follicular helper cells in end-stage germinal centers

Johanne T. Jacobsen, Wei Hu, Tiago B. R. Castro, Sigrid Solem, Alice Galante, Zeran Lin, Samuel J. Allon, Luka Mesin, Angelina M. Bilate, Ariën Schiepers, Alex K. Shalek, Alexander Y. Rudensky, Gabriel D. Victora

Science. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Science. 2021 Jul 16; 373(6552): eabe5146. Published online 2021 Jul 15. doi: 10.1126/science.abe5146

PMCID:: PMC9007630

Article PDF–3.6M

Select item 73059892.

CRISPR Screen in Regulatory T Cells Reveals Modulators of Foxp3

Jessica T. Cortez, Elena Montauti, Eric Shifrut, Jovylyn Gatchalian, Yusi Zhang, Oren Shaked, Yuanming Xu, Theodore L. Roth, Dimitre R. Simeonov, Yana Zhang, Siqi Chen, Zhongmei Li, Jonathan M. Woo, Josephine Ho, Ian A. Vogel, Grace Y. Prator, Bin Zhang, Youjin Lee, Zhaolin Sun, Igal Ifergan, Frédéric Van Gool, Diana C. Hargreaves, Jeffrey A. Bluestone, Alexander Marson, Deyu Fang

Nature. Author manuscript; available in PMC 2020 Oct 29.

Published in final edited form as: Nature. 2020 Jun; 582(7812): 416–420. Published online 2020 Apr 29. doi: 10.1038/s41586-020-2246-4

PMCID:: PMC7305989

Article PDF–4.2M

Select item 69490193.

Bile acid metabolites control Th17 and Treg cell differentiation

Saiyu Hang, Donggi Paik, Lina Yao, Eunha Kim, Trinath Jamma, Jingping Lu, Soyoung Ha, Brandon N. Nelson, Samantha P. Kelly, Lin Wu, Ye Zheng, Randy S. Longman, Fraydoon Rastinejad, A. Sloan Devlin, Michael R. Krout, Michael A. Fischbach, Dan R. Littman, Jun R. Huh

Nature. Author manuscript; available in PMC 2020 May 27.

Published in final edited form as: Nature. 2019 Dec; 576(7785): 143–148. Published online 2019 Nov 27. doi: 10.1038/s41586-019-1785-z

Correction in:: Nature. 2020 Feb 25

PMCID:: PMC6949019

Article PDF–4.7M

Select item 48628334.

A mechanism for expansion of regulatory T cell repertoire and its role in self tolerance

Yongqiang Feng, Joris van der Veeken, Mikhail Shugay, Ekaterina V Putintseva, Hatice U Osmanbeyoglu, Stanislav Dikiy, Beatrice E Hoyos, Bruno Moltedo, Saskia Hemmers, Piper Treuting, Christina S Leslie, Dmitriy M Chudakov, Alexander Y Rudensky

Nature. Author manuscript; available in PMC 2016 May 25.

Published in final edited form as: Nature. 2015 Dec 3; 528(7580): 132–136. Published online 2015 Nov 25. doi: 10.1038/nature16141

PMCID:: PMC4862833

Article PDF–4.5M

Select item 41979315.

A Novel, Human-Specific Interacting Protein Couples FOXP3 to a Chromatin Remodeling Complex that Contains KAP1/TRIM28

Chunjian Huang, Sunil Martin, Christian Pfleger, Jianguang Du, Jane H. Buckner, Jeffery A. Bluestone, James L. Riley, Steven F. Ziegler

J Immunol. Author manuscript; available in PMC 2014 Oct 15.

Published in final edited form as: J Immunol. 2013 May 1; 190(9): 4470–4473. Published online 2013 Mar 29. doi: 10.4049/jimmunol.1203561

PMCID:: PMC4197931

Article PDF–1.2M

Select item 38929726.

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

Kate S. Smigiel, Elizabeth Richards, Shivani Srivastava, Kerri R. Thomas, Jan C. Dudda, Kimberly D. Klonowski, Daniel J. Campbell

J Exp Med. 2014 Jan 13; 211(1): 121–136. doi: 10.1084/jem.20131142

Correction in:: J Exp Med. 2019 Aug 5; 216(8): 1965.

PMCID:: PMC3892972

Article PDF–3.6M

Select item 36810937.

An inherently bi-functional subset of Foxp3⁺ T helper cells is controlled by the transcription factor Eos

Madhav D. Sharma, Lei Huang, Jeong-Hyeon Choi, Eun-Joon Lee, James M. Wilson, Henrique Lemos, Fan Pan, Bruce R. Blazar, Drew M. Pardoll, Andrew L Mellor, Huidong Shi, David H. Munn

Immunity. Author manuscript; available in PMC 2014 May 23.

Published in final edited form as: Immunity. 2013 May 23; 38(5): 998–1012. Published online 2013 May 16. doi: 10.1016/j.immuni.2013.01.013

PMCID:: PMC3681093

Article PDF–1.9M

Select item 35750328.

Human T-Lymphotropic Virus Type 1-Induced CC Chemokine Ligand 22 Maintains a High Frequency of Functional FoxP3⁺ Regulatory T Cells

Frederic Toulza, Kisato Nosaka, Yuetsu Tanaka, Tiziana Schioppa, Frances Balkwill, Graham P. Taylor, Charles R. M. Bangham

J Immunol. Author manuscript; available in PMC 2013 Feb 18.

Published in final edited form as: J Immunol. 2010 Jul 1; 185(1): 183–189. Published online 2010 Jun 4. doi: 10.4049/jimmunol.0903846

PMCID:: PMC3575032

Article PDF–878K

Select item 34654659.

Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

Jared H. Rowe, James M. Ertelt, Lijun Xin, Sing Sing Way

Nature. Author manuscript; available in PMC 2013 Apr 4.

Published in final edited form as: Nature. 2012 Oct 4; 490(7418): 102–106. Published online 2012 Sep 26. doi: 10.1038/nature11462

PMCID:: PMC3465465

Article PDF–2.9M

Select item 338767810.

Control of T_H17/T_reg Balance by Hypoxia-inducible Factor 1

Eric V. Dang, Joseph Barbi, Huang-Yu Yang, Dilini Jinasena, Hong Yu, Ying Zheng, Zachary Bordman, Juan Fu, Young Kim, Hung-Rong Yen, Weibo Luo, Karen Zeller, Larissa Shimoda, Suzanne L. Topalian, Gregg L. Semenza, Chi V. Dang, Drew M. Pardoll, Fan Pan

Cell. Author manuscript; available in PMC 2012 Sep 2.

Published in final edited form as: Cell. 2011 Sep 2; 146(5): 772–784. Published online 2011 Aug 25. doi: 10.1016/j.cell.2011.07.033

PMCID:: PMC3387678

Article PDF–4.0M

Select item 327667911.

Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans

Jeff E. Mold, Shivkumar Venkatasubrahmanyam, Trevor D. Burt, Jakob Michaëlsson, Jose M. Rivera, Sofiya A. Galkina, Kenneth Weinberg, Cheryl A. Stoddart, Joseph M. McCune

Science. Author manuscript; available in PMC 2012 Feb 10.

Published in final edited form as: Science. 2010 Dec 17; 330(6011): 1695–1699. doi: 10.1126/science.1196509

Correction in:: volume 331 on page 534

PMCID:: PMC3276679

Article PDF–2.1M

Select item 314013912.

Foxp3⁺ regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens

Jared H. Rowe, James M. Ertelt, Marijo N. Aguilera, Michael A. Farrar, Sing Sing Way

Cell Host Microbe. Author manuscript; available in PMC 2012 Jul 21.

Published in final edited form as: Cell Host Microbe. 2011 Jul 21; 10(1): 54–64. doi: 10.1016/j.chom.2011.06.005

PMCID:: PMC3140139

Article PDF–1.4M

Select item 311575213.

Fat T_reg cells: a liaison between the immune and metabolic systems

Markus Feuerer, Laura Herrero, Daniela Cipolletta, Afia Naaz, Jamie Wong, Ali Nayer, Jongsoon Lee, Allison Goldfine, Christophe Benoist, Steven Shoelson, Diane Mathis

Nat Med. Author manuscript; available in PMC 2011 Jun 15.

Published in final edited form as: Nat Med. 2009 Aug; 15(8): 930–939. Published online 2009 Jul 26. doi: 10.1038/nm.2002

PMCID:: PMC3115752

Article PDF–1.9M

Select item 304320114.

The Ligase PIAS1 Restricts Natural Regulatory T Cell Differentiation by Epigenetic Repression

Bin Liu, Samuel Tahk, Kathleen M. Yee, Guoping Fan, Ke Shuai

Science. Author manuscript; available in PMC 2011 Feb 23.

Published in final edited form as: Science. 2010 Oct 22; 330(6003): 521–525. doi: 10.1126/science.1193787

PMCID:: PMC3043201

Article PDF–703K

Select item 300815915.

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Alexander Marson, Karsten Kretschmer, Garrett M. Frampton, Elizabeth S. Jacobsen, Julia K. Polansky, Kenzie D. MacIsaac, Stuart S. Levine, Ernest Fraenkel, Harald von Boehmer, Richard A. Young

Nature. Author manuscript; available in PMC 2010 Dec 22.

Published in final edited form as: Nature. 2007 Feb 22; 445(7130): 931–935. Published online 2007 Jan 21. doi: 10.1038/nature05478

PMCID:: PMC3008159

Article PDF–737K

Select item 288418716.

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Ye Zheng, Steven Josefowicz, Ashutosh Chaudhry, Xiao P. Peng, Katherine Forbush, Alexander Y. Rudensky

Nature. Author manuscript; available in PMC 2010 Jun 14.

Published in final edited form as: Nature. 2010 Feb 11; 463(7282): 808–812. Published online 2010 Jan 13. doi: 10.1038/nature08750

PMCID:: PMC2884187

Article PDF–725K

Select item 286479117.

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T_H2 responses

Ye Zheng, Ashutosh Chaudhry, Arnold Kas, Paul deRoos, Jeong M. Kim, Tin-Tin Chu, Lynn Corcoran, Piper Treuting, Ulf Klein, Alexander Y. Rudensky

Nature. Author manuscript; available in PMC 2010 May 5.

Published in final edited form as: Nature. 2009 Mar 19; 458(7236): 351–356. Published online 2009 Feb 1. doi: 10.1038/nature07674

PMCID:: PMC2864791

Article PDF–2.9M

Select item 285970318.

Eos mediates Foxp3-dependent gene silencing in regulatory T cells

Fan Pan, Hong Yu, Eric V. Dang, Joseph Barbi, Xiaoyu Pan, Joseph F. Grosso, Dinili Jinasena, Sudarshana M. Sharma, Erin M. McCadden, Derese Getnet, Charles G. Drake, Jun O. Liu, Michael C. Ostrowski, Drew M. Pardoll

Science. Author manuscript; available in PMC 2010 Apr 26.

Published in final edited form as: Science. 2009 Aug 28; 325(5944): 1142–1146. Published online 2009 Aug 20. doi: 10.1126/science.1176077

PMCID:: PMC2859703

Article PDF–1.9M

Select item 276917319.

Tregs control the development of symptomatic West Nile virus infection in humans and mice

Marion C. Lanteri, Katie M. O’Brien, Whitney E. Purtha, Mark J. Cameron, Jennifer M. Lund, Rachel E. Owen, John W. Heitman, Brian Custer, Dale F. Hirschkorn, Leslie H. Tobler, Nancy Kiely, Harry E. Prince, Lishomwa C. Ndhlovu, Douglas F. Nixon, Hany T. Kamel, David J. Kelvin, Michael P. Busch, Alexander Y. Rudensky, Michael S. Diamond, Philip J. Norris

J Clin Invest. 2009 Nov 2; 119(11): 3266–3277. Published online 2009 Oct 12. doi: 10.1172/JCI39387

PMCID:: PMC2769173

Article PDF–1.5M

Select item 256113420.

Anti tumour necrosis-α therapy increases the number of FOXP3⁺ regulatory T cells in children affected by Crohn's disease

Ida Ricciardelli, Keith J Lindley, Marco Londei, Sonia Quaratino

Immunology. 2008 Oct; 125(2): 178–183. doi: 10.1111/j.1365-2567.2008.02839.x

PMCID:: PMC2561134

Article PDF–219K

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