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Select item 105236651.

Human osteoarthritic articular cartilage stem cells suppress osteoclasts and improve subchondral bone remodeling in experimental knee osteoarthritis partially by releasing TNFAIP3

Zhi-Ling Li, Xiao-Tong Li, Rui-Cong Hao, Fei-Yan Wang, Yu-Xing Wang, Zhi-Dong Zhao, Pei-Lin Li, Bo-Feng Yin, Ning Mao, Li Ding, Heng Zhu

Stem Cell Res Ther. 2023; 14: 253. Published online 2023 Sep 27. doi: 10.1186/s13287-023-03411-7

PMCID:: PMC10523665

Article PDF–16M

Select item 102845992.

A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation

Elma El Khouri, Farah Diab, Camille Louvrier, Eman Assrawi, Aphrodite Daskalopoulou, Alexandre Nguyen, William Piterboth, Samuel Deshayes, Alexandra Desdoits, Bruno Copin, Florence Dastot Le Moal, Sonia Athina Karabina, Serge Amselem, Achille Aouba, Irina Giurgea

eLife. 2023; 12: e81280. Published online 2023 Jun 21. doi: 10.7554/eLife.81280

PMCID:: PMC10284599

Article PDF–4.1M

Select item 99721393.

TNFAIP3 mutation is an independent poor overall survival factor for patients with T‐cell acute lymphoblastic leukemia

Cunte Chen, Lingling Zhou, Lihua Zhu, Gengxin Luo, Liang Wang, Chengwu Zeng, Hongsheng Zhou, Yangqiu Li

Cancer Med. 2023 Feb; 12(4): 3952–3961. Published online 2022 Sep 3. doi: 10.1002/cam4.5196

PMCID:: PMC9972139

Article PDF–9.0M

Select item 94467124.

TNFAIP3 mutation causing haploinsufficiency of A20 with a hemophagocytic lymphohistiocytosis phenotype: a report of two cases

Nahid Aslani, Kosar Asnaashari, Nima Parvaneh, Mohammad Shahrooei, Maryam Sotoudeh-Anvari, Farhad Shahram, Vahid Ziaee

Pediatr Rheumatol Online J. 2022; 20: 78. Published online 2022 Sep 5. doi: 10.1186/s12969-022-00735-1

PMCID:: PMC9446712

Article PDF–694K

Select item 93098525.

Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Lilla ERDEI, Beáta Szilvia BOLLA, Renáta BOZÓ, Gábor TAX, Edit URBÁN, Katalin BURIÁN, Lajos KEMÉNY, Kornélia SZABÓ

Acta Derm Venereol. 2021; 101(1): 1470. Published online 2021 Jan 13. doi: 10.2340/00015555-3707

PMCID:: PMC9309852

Article PDF–4.3M

Select item 92552686.

The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy

Shaolin Mei, Hongyu Ruan, Qi Ma, Wei-Dong Yao

Brain Res. Author manuscript; available in PMC 2022 Jul 5.

Published in final edited form as: Brain Res. 2020 Jan 15; 1727: 146569. Published online 2019 Nov 26. doi: 10.1016/j.brainres.2019.146569

PMCID:: PMC9255268

Article PDF–3.8M

Select item 88757987.

A20 Attenuates the Fibrotic Response in the Trabecular Meshwork

Philip Mzyk, Emma G. Zalog, Colleen M. McDowell

Int J Mol Sci. 2022 Feb; 23(4): 1928. Published online 2022 Feb 9. doi: 10.3390/ijms23041928

PMCID:: PMC8875798

Article PDF–3.1M

Select item 88257788.

Identification of a Novel Mutation in TNFAIP3 in a Family With Poly-Autoimmunity

Marianna Nicoletta Rossi, Silvia Federici, Andrea Uva, Chiara Passarelli, Camilla Celani, Ivan Caiello, Valentina Matteo, Stefano Petrocchi, Eva Piano Mortari, Fabrizio De Benedetti, Giusi Prencipe, Antonella Insalaco

Front Immunol. 2022; 13: 804401. Published online 2022 Jan 26. doi: 10.3389/fimmu.2022.804401

PMCID:: PMC8825778

Article PDF–2.2M

Select item 85936799.

A Previously Undiscovered Circular RNA, circTNFAIP3, and Its Role in Coronavirus Replication

Liuyang Du, Xingbo Wang, Junli Liu, Jiarong Li, Shengnan Wang, Jing Lei, Jiyong Zhou, Jinyan Gu

mBio. 2021 Nov-Dec; 12(6): e02984-21. Published online 2021 Nov 16. doi: 10.1128/mBio.02984-21

PMCID:: PMC8593679

Article PDF–5.4M

Select item 786675810.

Functional analysis of novel A20 variants in patients with atypical inflammatory diseases

Saori Kadowaki, Kunio Hashimoto, Toyoki Nishimura, Kenichi Kashimada, Tomonori Kadowaki, Norio Kawamoto, Kohsuke Imai, Satoshi Okada, Hirokazu Kanegane, Hidenori Ohnishi

Arthritis Res Ther. 2021; 23: 52. Published online 2021 Feb 6. doi: 10.1186/s13075-021-02434-w

PMCID:: PMC7866758

Article PDF–1.4M

Select item 776249511.

TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy

Jie Chen, Yufei Ma, Zhijie Yang, Haiyang Lan, Guangliang Liu, Ye Zhang, Huiqiang Xia, Xiaofang Wang, Fei Han, Xiaolin Tu, Bo Liu

Aging (Albany NY) 2020 Dec 15; 12(23): 24242–24254. Published online 2020 Nov 20. doi: 10.18632/aging.104160

PMCID:: PMC7762495

Article PDF–1.5M

Select item 773318712.

A20 regulates the therapeutic effect of anti-PD-1 immunotherapy in melanoma

Weinan Guo, Jinyuan Ma, Sen Guo, Huina Wang, Sijia Wang, Qiong Shi, Lin Liu, Tao Zhao, Fengfan Yang, Shuyang Chen, Jianru Chen, Jianhong Zhao, Chen Yu, Xiuli Yi, Yuqi Yang, Jingjing Ma, Qingrong Ni, Guannan Zhu, Tianwen Gao, Chunying Li

J Immunother Cancer. 2020; 8(2): e001866. Published online 2020 Dec 9. doi: 10.1136/jitc-2020-001866

PMCID:: PMC7733187

Article PDF–12M

Select item 761150213.

Downregulation of A20 promotes immune escape of lung Adenocarcinomas

Kristina Breitenecker, Monika Homolya, Andreea C. Luca, Veronika Lang, Christoph Trenk, Georg Petroczi, Julian Mohrherr, Jaqueline Horvath, Stefan Moritsch, Lisa Haas, Margarita Kurnaeva, Robert Eferl, Dagmar Stoiber, Richard Moriggl, Martin Bilban, Anna C. Obenauf, Christiane Ferran, Balazs Dome, Viktoria Laszlo, Balázs Győrffy, Katalin Dezso, Judit Moldvay, Emilio Casanova, Herwig P. Moll

Sci Transl Med. Author manuscript; available in PMC 2022 Jan 7.

Published in final edited form as: Sci Transl Med. 2021 Jul 7; 13(601): eabc3911. Published online 2021 Jul 7. doi: 10.1126/scitranslmed.abc3911

PMCID:: PMC7611502

Article PDF–3.3M

Select item 751135914.

A20 promotes melanoma progression via the activation of Akt pathway

Jinyuan Ma, Huina Wang, Sen Guo, Xiuli Yi, Tao Zhao, Yu Liu, Qiong Shi, Tianwen Gao, Chunying Li, Weinan Guo

Cell Death Dis. 2020 Sep; 11(9): 794. Published online 2020 Sep 23. doi: 10.1038/s41419-020-03001-y

PMCID:: PMC7511359

Article PDF–2.9M

Select item 738162115.

Identification of TNFAIP3 as relapse biomarker and potential therapeutic target for MOG antibody associated diseases

Shrishti Saxena, Hrishikesh Lokhande, Grace Gombolay, Radhika Raheja, Timothy Rooney, Tanuja Chitnis

Sci Rep. 2020; 10: 12405. Published online 2020 Jul 24. doi: 10.1038/s41598-020-69182-w

PMCID:: PMC7381621

Article PDF–2.3M

Select item 734859116.

A20 Haploinsufficiency in a Chinese Patient With Intestinal Behcet's Disease-Like Symptoms: A Case Report

Yu Chen, Huanjun Huang, Yao He, Minhu Chen, Ursula Seidler, De'an Tian, Fang Xiao

Front Immunol. 2020; 11: 1414. Published online 2020 Jul 3. doi: 10.3389/fimmu.2020.01414

PMCID:: PMC7348591

Article PDF–944K

Select item 707870017.

A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis

Yajie Li, Erin C. Mooney, Xia-Juan Xia, Nitika Gupta, Sinem Esra Sahingur

Front Immunol. 2020; 11: 365. Published online 2020 Mar 10. doi: 10.3389/fimmu.2020.00365

PMCID:: PMC7078700

Article PDF–4.1M

Select item 694877018.

A20 as an immune tolerance factor can determine islet transplant outcomes

Nathan W. Zammit, Stacey N. Walters, Karen L. Seeberger, Philip J. O’Connell, Gregory S. Korbutt, Shane T. Grey

JCI Insight. 2019 Nov 1; 4(21): e131028. Published online 2019 Nov 1. doi: 10.1172/jci.insight.131028

PMCID:: PMC6948770

Article PDF–17M

Select item 673263619.

TNFAIP3 Gene Polymorphisms in Three Common Autoimmune Diseases: Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Primary Sjogren Syndrome—Association with Disease Susceptibility and Clinical Phenotypes in Italian Patients

C. Ciccacci, A. Latini, C. Perricone, P. Conigliaro, S. Colafrancesco, F. Ceccarelli, R. Priori, F. Conti, R. Perricone, G. Novelli, P. Borgiani

J Immunol Res. 2019; 2019: 6728694. Published online 2019 Aug 27. doi: 10.1155/2019/6728694

PMCID:: PMC6732636

Article PDF–659K

Select item 670990220.

High A20 expression negatively impacts survival in patients with breast cancer

Chang Ik Yoon, Sung Gwe Ahn, Soong June Bae, Yun Jin Shin, Chihwan Cha, So Eun Park, Ji-Hyung Lee, Akira Ooshima, Hye Sun Lee, Kyung-Min Yang, Seong-Jin Kim, Seok Hee Park, Joon Jeong

PLoS One. 2019; 14(8): e0221721. Published online 2019 Aug 26. doi: 10.1371/journal.pone.0221721

PMCID:: PMC6709902

Article PDF–1.1M

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