PMC Links for Gene (Select 2280) - PMC

Zhongguang Li, Ying Cui, Qinchun Duan, Jianfei Zhang, Danyang Shao, Xixi Cao, Yuru Gao, Shulin Wang, Jiali Li, Odell D. Jones, Xinjuan Lei, Liyang Wang, Xin Zhou, Mengmeng Xu, Jianjie Ma, Yingli Liu, Xuehong Xu

Int J Mol Sci. 2022 Nov; 23(21): 12797. Published online 2022 Oct 24. doi: 10.3390/ijms232112797

PMCID:: PMC9659304

Article PDF–5.8M

Select item 49558704.

Electrostatic effects on the folding stability of FKBP12

Jyotica Batra, Harianto Tjong, Huan-Xiang Zhou

Protein Eng Des Sel. 2016 Aug; 29(8): 301–308. Published online 2016 Jul 20. doi: 10.1093/protein/gzw014

PMCID:: PMC4955870

Article PDF–212K

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Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization

Ying-Hui Yan, Yan Wang, Lan-Xue Zhao, Shan Jiang, Horace H. Loh, Ping-Yee Law, Hong-Zhuan Chen, Yu Qiu

Neurosci Lett. Author manuscript; available in PMC 2015 Apr 30.

Published in final edited form as: Neurosci Lett. 2014 Apr 30; 566: 231–235. Published online 2014 Mar 6. doi: 10.1016/j.neulet.2014.02.059

PMCID:: PMC4010564

Article PDF–875K

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Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6

Hui Chen, Sourajit M. Mustafi, David M. LeMaster, Zhong Li, Annie Héroux, Hongmin Li, Griselda Hernández

Acta Crystallogr D Biol Crystallogr. 2014 Mar 1; 70(Pt 3): 636–646. Published online 2014 Feb 15. doi: 10.1107/S1399004713032112

PMCID:: PMC3949516

Article PDF–994K

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FKBP12.6 Activates RyR1: Investigating the Amino Acid Residues Critical for Channel Modulation

Elisa Venturi, Elena Galfré, Fiona O’Brien, Samantha J. Pitt, Stuart Bellamy, Richard B. Sessions, Rebecca Sitsapesan

Biophys J. 2014 Feb 18; 106(4): 824–833. doi: 10.1016/j.bpj.2013.12.041

PMCID:: PMC3945099

Article PDF–1.5M

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Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12

Sourajit M. Mustafi, Matthew Brecher, Jing Zhang, Hongmin Li, David M. Lemaster, Griselda Hernández

Biochem J. 2014 Mar 15; 458(Pt 3): 525–536. Prepublished online 2014 Jan 10. Published online 2014 Feb 28. doi: 10.1042/BJ20131429

PMCID:: PMC3940039

Article PDF–1.5M

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Analysing the visible conformational substates of the FK506-binding protein FKBP12

Sourajit M. Mustafi, Hui Chen, Hongmin Li, David M. LeMaster, Griselda Hernández

Biochem J. 2013 Aug 1; 453(Pt 3): 371–380. Prepublished online 2013 May 21. Published online 2013 Jul 12. doi: 10.1042/BJ20130276

PMCID:: PMC3727217

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Requirements for peptidyl-prolyl isomerization activity: A comprehensive mutational analysis of the substrate-binding cavity of FK506-binding protein 12

Teikichi Ikura, Nobutoshi Ito

Protein Sci. 2007 Dec; 16(12): 2618–2625. doi: 10.1110/ps.073203707

PMCID:: PMC2222811

Article PDF–324K

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PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

Steven Reiken, Alain Lacampagne, Hua Zhou, Aftab Kherani, Stephan E. Lehnart, Chris Ward, Fannie Huang, Marta Gaburjakova, Jana Gaburjakova, Nora Rosemblit, Michelle S. Warren, Kun-lun He, Geng-hua Yi, Jie Wang, Daniel Burkhoff, Guy Vassort, Andrew R. Marks

J Cell Biol. 2003 Mar 17; 160(6): 919–928. doi: 10.1083/jcb.200211012

PMCID:: PMC2173774

Article PDF–296K

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Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin.

N Maki, F Sekiguchi, J Nishimaki, K Miwa, T Hayano, N Takahashi, M Suzuki

Proc Natl Acad Sci U S A. 1990 Jul; 87(14): 5440–5443. doi: 10.1073/pnas.87.14.5440

PMCID:: PMC54340

Summary Page Browse PDF–972K

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A ligand-reversible dimerization system for controlling protein–protein interactions

Carl T. Rollins, Victor M. Rivera, Derek N. Woolfson, Terence Keenan, Marcos Hatada, Susan E. Adams, Lawrence J. Andrade, David Yaeger, Marie Rose van Schravendijk, Dennis A. Holt, Michael Gilman, Tim Clackson

Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13): 7096–7101. Published online 2000 Jun 13. doi: 10.1073/pnas.100101997

PMCID:: PMC16505

Article PDF–325K

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FKBP51 promotes invasion and migration by increasing the autophagic degradation of TIMP3 in clear cell renal cell carcinoma

Shaowei Mao, Di Zhang, Luan Chen, Jie Tan, Yunpeng Chu, Sijia Huang, Wenqi Zhou, Hengwei Qin, Qinghua Xia, Yueran Zhao, Rongxiu Li, Shengying Qin, Muyun Wei

Cell Death Dis. 2021 Oct; 12(10): 899. Published online 2021 Oct 1. doi: 10.1038/s41419-021-04192-8

PMCID:: PMC8486832

Article PDF–7.5M

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Ubiquitylation Directly Induces Fold Destabilization of Proteins

Daichi Morimoto, Erik Walinda, Harumi Fukada, Kenji Sugase, Masahiro Shirakawa

Sci Rep. 2016; 6: 39453. Published online 2016 Dec 19. doi: 10.1038/srep39453

PMCID:: PMC5172356

Article PDF–1.2M

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Everolimus induces Met inactivation by disrupting the FKBP12/Met complex

Lucia Raimondo, Valentina D'Amato, Alberto Servetto, Roberta Rosa, Roberta Marciano, Luigi Formisano, Concetta Di Mauro, Roberta Clara Orsini, Priscilla Cascetta, Paola Ciciola, Ana Paula De Maio, Maria Flavia Di Renzo, Sandro Cosconati, Agostino Bruno, Antonio Randazzo, Filomena Napolitano, Nunzia Montuori, Bianca Maria Veneziani, Sabino De Placido, Roberto Bianco

Oncotarget. 2016 Jun 28; 7(26): 40073–40084. Published online 2016 May 19. doi: 10.18632/oncotarget.9484

PMCID:: PMC5129993

Article PDF–3.2M

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Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect

Chia-Sui Sun, Chi-Chang Lee, Yi-Ni Li, Sunny Yao-Chen Yang, Chih-Hsiang Lin, Yi-Che Chang, Po-Fan Liu, Ruei-Yu He, Chih-Hsien Wang, Wenlung Chen, Yijuang Chern, Joseph Jen-Tse Huang

Sci Rep. 2015; 5: 14992. Published online 2015 Oct 9. doi: 10.1038/srep14992